Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

New approach can track how superbugs travel among and within health care facilities

Killer bacteria – ones that have out-evolved our best antibiotics -- may not go away anytime soon. But a new approach to tracking their spread could eventually give us a fighting chance to keep their death toll down.

23 Nov 2017

Scientists discover how tumor environment can trigger metastatic behavior in cancer cells

A team of bioengineers and bioinformaticians at the University of California San Diego have discovered how the environment surrounding a tumor can trigger metastatic behavior in cancer cells.

22 Nov 2017

Researchers identify previously unknown breast cell types

A joint effort by breast cancer researchers and bioinformaticians has provided new insights into the molecular changes that drive breast development.

21 Nov 2017

Researchers develop computer program to find new indications for old drugs

Researchers at the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine have developed a computer program to find new indications for old drugs.

16 Nov 2017

Researchers use novel computational tool to understand complex disease processes

Hypertension and heart disease arise from many contributing and interacting factors: genetics, food, and exercise, as well as problems with heart, liver, or kidney function.

14 Nov 2017

University of Michigan and AstraZeneca partner to improve treatment for CKD patients

Patients with Chronic Kidney Disease (CKD) may benefit from a new collaboration between the University of Michigan and AstraZeneca who have partnered to develop a new therapeutic strategy for treatment.

10 Nov 2017

Researchers develop new method that can curb spread of superbugs

Researchers from ITMO University and Center of Physical and Chemical Medicine developed an algorithm capable of tracking the spread of antibiotic resistance genes in gut microbiota DNA and revealed additional evidence of resistance genes transfer between different bacterial species.

10 Nov 2017

Danish study sheds light on why whole grains are healthy

When overweight adults exchange refined grain products - such as white bread and pasta - with whole grain varieties, they eat less, they lose weight and the amount of inflammation in their bodies decreases. These are some of the findings of a large Danish study headed by the National Food Institute, Technical University of Denmark.

2 Nov 2017

Repositive introduces first Global PDX Directory at AACR conference

The first Global PDX Directory for proprietary and open source PDX models is being introduced by Cambridge (UK) based benefit corporation, Repositive, at the American Association for Cancer Research’sInternational Conference, on Molecular Targets and Cancer Therapeutics, hosted in conjunction with the European Organisation for Research and Treatment of Cancer and the National Cancer Institute, in Philadelphia, USA, 26-30 October 2017.

1 Nov 2017

Study shows effects of prenatal BPA exposure at low levels in developing rodent brain

New research from North Carolina State University reveals that prenatal exposure to bisphenol A (BPA) at levels below those currently considered safe for humans affects gene expression related to sexual differentiation and neurodevelopment in the developing rat brain.

31 Oct 2017

SU2C and its collaborators announce four teams to intercept cancer at earliest stages

Stand Up To Cancer, joined by the Lustgarten Foundation for Pancreatic Cancer Research, LUNGevity, and the American Lung Association, announced today four teams of top researchers who will carry out an attack on cancers of the lung and pancreas using a radical new approach of “interception” of cancers at very early stages, when they can be more successfully treated.

31 Oct 2017

Study reveals unique molecules in the blood of people with MS

A breakthrough study led by the University of Sydney's Brain and Mind Centre and Royal Prince Alfred Hospital has revealed unique molecules in the blood of people with Multiple Sclerosis (MS) that could become definitive diagnostic biomarkers of the world's most common neurologic disability in young adults.

30 Oct 2017

Cancer researchers make breakthrough in identifying genetic changes during immunotherapy

For some cancer patients, the road to remission and healing can have its share of speed bumps. That's particularly true of patients with non-small cell lung cancer (NSCLC) who develop a secondary, or acquired, resistance to immunotherapy, which initially was effective against their tumors.

28 Oct 2017

TGen project to develop standard operating procedures for single-cell RNA sequencing

The Translational Genomics Research Institute today announced grant support from the Chan Zuckerberg Initiative donor advised fund, an advised fund of the Silicon Valley Community Foundation, that will help revolutionize how researchers identify the genetic source of diseases and how best to treat each patient.

17 Oct 2017

Researchers use mixed realty viewer to visualize complex biological networks in 3D

They call it the "hairy ball." It's an unflattering name for two-dimensional representations of a complex biological network, a depiction of a system of linkages and connections so complex and dense that "it looks like a big mess," said Dmitry Korkin, PhD, associate professor of computer science at Worcester Polytechnic Institute and director of the university's bioinformatics and computational biology program.

13 Oct 2017

Forsyth researchers win $5.4 million NIH award to pursue research on oral microbes

A research team led by the Forsyth Institute today received a $5.4 million award from the National Institutes of Health to pursue revolutionary research of microbes living in the mouth and within the human body.

6 Oct 2017

Researchers uncover promising targets for development of drugs against leishmaniasis

Brazilian researchers at the University of São Paulo's Bioscience Institute (IB-USP) are starting to unravel the molecular mechanisms by which the parasite that causes cutaneous leishmaniasis manages to circumvent the host organism's defenses and infect new cells.

5 Oct 2017

Researchers improve genetic decoding of neurodevelopmental disorders

A result that will help in the future diagnosis of children with neurodevelopmental disorders, such as intellectual disability, autism or schizophrenia.

5 Oct 2017

Clarivate Analytics includes eBooks for coverage in Book Citation Index

Clarivate Analytics has recently included the following 16 eBooks for coverage in Book Citation Index. The Book Citation Index in Web of Science™ Core Collection connects a library's book collection to powerful new discovery tools, giving researchers the ability to quickly and easily identify and access the most relevant books.

30 Sep 2017

Forgotten strands of DNA induce 'big bang' of immune cell development

Intricate human physiological features such as the immune system require exquisite formation and timing to develop properly. Genetic elements must be activated at just the right moment, across vast distances of genomic space.

21 Sep 2017