Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Scientists develop computational method to map cancer progression

A team of scientists has developed a computational method to map cancer progression, an advance that offers new insights into the factors that spur this affliction as well as new ways of selecting effective therapies.

28 Jun 2016

Insilico Medicine collaborates with Asia Genomics to develop advanced personalized longevity suite

Insilico Medicine Inc, a big data analytics company located at the Emerging Technology Centers at the Johns Hopkins University at Eastern, announced an agreement with Asia Genomics, a Singapore-based rapidly growing molecular diagnostics company specializing in clinical genomics & genetic testing operating in major Asian countries including Vietnam, Malaysia and China.

22 Jun 2016

VUMC researchers aim to decode genetic underpinnings of human immune system

Researchers at Vanderbilt University Medical Center this month began recruiting volunteers to participate in a clinical trial aimed at decoding the human "immunome," the genetic underpinnings of the immune system.

22 Jun 2016

Experts use next-generation genetic sequencing to diagnose suspected brain infections

In a proof-of-principle study, a team of physicians and bioinformatics experts at Johns Hopkins reports they were able to diagnose or rule out suspected brain infections using so called next-generation genetic sequencing of brain tissue samples.

21 Jun 2016

Researchers develop AI-powered systems to make pathologic diagnoses more accurate

Pathologists have been largely diagnosing disease the same way for the past 100 years, by manually reviewing images under a microscope. But new work suggests that computers can help doctors improve accuracy and significantly change the way cancer and other diseases are diagnosed.

20 Jun 2016

Scientists develop new software program that can help compare large amounts of metagenomes

Scientists from ITMO University, the Federal Research and Clinical Centre of Physical-Chemical Medicine and MIPT have developed a software program enabling them to quickly compare sets of DNA of microorganisms living in different environments. The researchers have already suggested exactly how the new program could be applied in practice.

16 Jun 2016

Adaptive Biotechnologies demonstrates use of high-throughput sequencing platform for MRD

Adaptive Biotechnologies, the leader in combining next-generation sequencing (NGS) and expert bioinformatics to profile T- and B-cell receptors of the adaptive immune system, and collaborators will be presenting five studies demonstrating how Adaptive’s high-throughput sequencing platform enables diagnosis, detection and assessment of prognosis in hematological malignances and has increased sensitivity over flow cytometry.

16 Jun 2016

Complex 36-point therapeutic personalized program can help reverse memory loss in early AD patients

Results from quantitative MRI and neuropsychological testing show unprecedented improvements in ten patients with early Alzheimer's disease (AD) or its precursors following treatment with a programmatic and personalized therapy. Results from an approach dubbed metabolic enhancement for neurodegeneration are now available online in the journal Aging.

16 Jun 2016

EPFL researchers reprogram TAMs to prevent tumor metastasis

One of the major obstacles with treating cancer is that tumors can conscript the body's immune cells and make them work for them. Researchers at EPFL have now found a way to reclaim the corrupted immune cells, turn them into signals for the immune system to attack the tumor, and even prevent metastasis.

14 Jun 2016

About 30% of iPSCs not safe for clinical use, report multi-institutional researchers

As the promise of using regenerative stem cell therapies draws closer, a consortium of biomedical scientists reports about 30 percent of induced pluripotent stem cells they analyzed from 10 research institutions were genetically unstable and not safe for clinical use.

10 Jun 2016

UCLA scientists develop statistical method for conducting survival analysis of cancer patients

People with cancer are often told by their doctors approximately how long they have to live, and how well they will respond to treatments, but what if there were a way to improve the accuracy of doctors' predictions?

9 Jun 2016

NMR-based metabolomics: an interview with Prof. Claudio Luchinat

Professor Claudio Luchinat, University of Florence and co-founder of the Magnetic Resonance Center (CERM), speaks to News-Medical about his research in NMR-based metabolomics.

From Bruker BioSpin - NMR, EPR and Imaging 9 Jun 2016

Life Extension, Insilico Medicine team up to identify novel biomarkers of human aging

Life Extension (use different web link to highlight our technical attributes), a Florida-based organization established in the early 1980s is dedicated to extending healthy human longevity.

8 Jun 2016

Experts highlight need for change in neuroscience training

Call them the Brain Generation -- the tens of thousands of college and graduate students working toward degrees in neuroscience, and the high school students who want to join them someday.

6 Jun 2016

BRCA gene mutations raise risk of breast, ovarian and other cancers

BRCA Share, a public-private BRCA gene datashare initiative, today announced the public release of a large collection of new data on genetic variants in the BRCA1 and BRCA2 genes.

From Quest Diagnostics 2 Jun 2016

Buck researchers identify new, potential drug targets for sporadic PD

Research at the Buck Institute shows the same mechanisms that lead to neuronal cell death in mice genetically fated to develop Parkinson's disease (PD) are involved in the much more common sporadic form of the age-related, neurodegenerative disorder that robs people of the ability to move normally.

2 Jun 2016

Applying deep neural networks to predict pharmacologic properties of drugs and drug repurposing

Deep learning, frequently referred to as artificial intelligence, a branch of machine learning utilizing multiple layers of neurons to model high-level abstractions in data, has outperformed humans in tasks including image, text and voice recognition, autonomous driving and others, and is now being applied to drug discovery and biomarker development.

28 May 2016

Small drug-like molecule that alters perception of food may hold key to extending human healthspan

Researchers at the Buck Institute have shown a new effect on aging via a small drug-like molecule that alters the perception of food in the nematode C. elegans. Publishing in Aging Cell, researchers "tricked" the worm's metabolism into a state of caloric restriction, extending the animal's lifespan by 50 percent.

27 May 2016

UT Southwestern study offers more insight into cholesterol transporter

Using X-ray crystallography, UT Southwestern Medical Center researchers have determined the 3-D atomic structure of a human sterol transporter that helps maintain cholesterol balance.

27 May 2016

ANK3 and other genes may play key role in affecting mood, stress and longevity

The visible impacts of depression and stress that can be seen in a person's face -- and contribute to shorter lives -- can also be found in alterations in genetic activity, according to newly published research.

24 May 2016

Bioinformatics News and Research

Further Reading

Scientists develop computational method to map cancer progression

Insilico Medicine collaborates with Asia Genomics to develop advanced personalized longevity suite

VUMC researchers aim to decode genetic underpinnings of human immune system

Experts use next-generation genetic sequencing to diagnose suspected brain infections

Researchers develop AI-powered systems to make pathologic diagnoses more accurate

Scientists develop new software program that can help compare large amounts of metagenomes

Adaptive Biotechnologies demonstrates use of high-throughput sequencing platform for MRD

Complex 36-point therapeutic personalized program can help reverse memory loss in early AD patients

EPFL researchers reprogram TAMs to prevent tumor metastasis

About 30% of iPSCs not safe for clinical use, report multi-institutional researchers

UCLA scientists develop statistical method for conducting survival analysis of cancer patients

NMR-based metabolomics: an interview with Prof. Claudio Luchinat

Life Extension, Insilico Medicine team up to identify novel biomarkers of human aging

Experts highlight need for change in neuroscience training

BRCA gene mutations raise risk of breast, ovarian and other cancers

Buck researchers identify new, potential drug targets for sporadic PD

Applying deep neural networks to predict pharmacologic properties of drugs and drug repurposing

Small drug-like molecule that alters perception of food may hold key to extending human healthspan

UT Southwestern study offers more insight into cholesterol transporter

ANK3 and other genes may play key role in affecting mood, stress and longevity

Lab Diagnostics and Automation - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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