Biomarker News and Research

RSS

A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Scientists receive $4M grant to identify biomarker for secondary injuries associated with brain

In an effort to lower medical costs, identify patients at risk for injury, and speed patient recovery, scientists will attempt to identify a molecular signal that indicates severity of brain-injury during a $4 million, five-year federal grant to Barrow Neurological Institute at St. Joseph's Hospital and Medical Center, Phoenix Children's Hospital and the Translational Genomics Research Institute (TGen).

5 Dec 2013

Biohit Oyj to distribute Dynex automated ELISA systems with Gastropanel

Finnish healthcare company Biohit Oyj and American company Dynex Technologies, Inc. have signed an agreement for the distribution of the two-microplate DS2®, four-microplate DSX® and 12-microplate Agility® automated ELISA (enzyme-linked immunosorbent assay) processing systems, for use with the Biohit Oyj GastroPanel.

4 Dec 2013

VolitionRx's two-assay test can detect 85% of colorectal cancer, more than 50% of precancerous polyps

VolitionRx Limited, a life sciences company focused on developing blood-based diagnostic tests for different types of cancer, today releases new data showing that when combining two of its proprietary NuQ assays into one test, they can achieve 85% detection rates at 85% specificity for colorectal cancer. The data also shows that Volition’s two-assay test can detect more than 50% of precancerous polyps. These new findings come from its ongoing prospective study with CHU Dinant Godinne | UCL Namur Hospital in Belgium.

4 Dec 2013

A new approach for treating colorectal cancer

Scientists and surgeons at Princess Margaret Cancer Centre have discovered a promising new approach to treating colorectal cancer by disarming the gene that drives self-renewal in stem cells that are the root cause of disease, resistance to treatment and relapse.

4 Dec 2013

Lexicon announces top-line results from initial Phase 2 study of LX1033 for treatment of IBS-d

Lexicon Pharmaceuticals, Inc. today announced top-line results from an initial Phase 2 study exploring the use of LX1033 in diarrhea-predominant irritable bowel syndrome. LX1033 is an investigational drug that inhibits serotonin synthesis in the gastrointestinal tract. Serotonin is a neurotransmitter that has been shown to play a role in the symptoms of irritable bowel syndrome.

3 Dec 2013

IRCM researcher sheds light on inconsistencies between pharmacogenomic studies

A bioinformatics expert at the IRCM, Benjamin Haibe-Kains, recently published an article stressing the importance of standardizing drug screening studies in the prestigious scientific journal Nature. The study supports the need for further development and standardization to improve the reproducibility of drug screening studies, as they are important in identifying new therapeutic agents and their potential combinations with existing drugs.

3 Dec 2013

New finding links obesity and high-fat, high-sugar diets with changes in inflammatory status

Scientists have moved a step closer to an "obesity drug" that may block the effects of diets high in sugar and fats. In a new research report published in the December 2013 issue of The FASEB Journal, scientists show that there is an abnormal amount of an inflammatory protein called PAR2 in the abdominal fat tissue of overweight and obese humans and rats.

3 Dec 2013

New biomarkers to improve diagnostics of prostate cancer

New biomarkers will improve diagnostics of endemic diseases in future, such as prostate cancer. Their mission: to recognize the tumor earlier and classify it more precisely - thereby helping avoid unnecessary operations.

2 Dec 2013

Researchers discover promising new approach for colorectal cancer treatment

2 Dec 2013

New whitepaper examines main strategies employed to optimise target enrichment for NGS assays

Oxford Gene Technology, provider of innovative genetics research and biomarker solutions to advance molecular medicine, has produced a free whitepaper titled ‘The importance of enrichment assay choice and optimisation for confident variant detection.’ The paper investigates the main strategies employed to optimise target enrichment for next generation sequencing assays, assisting researchers to make informed decisions when designing studies.

From Oxford Gene Technology 30 Nov 2013

Diagnosing colonic polyps: an interview with Dr. Haili Wang, Metabolomic Technologies Inc. (MTI)

Colorectal cancer is a leading cause of death in North America, but it is preventable if found at the colonic polyp stage. Currently, only 39% of colorectal cancer cases in the US are diagnosed at an early and treatable stage.

28 Nov 2013

Seed grants support cancer diagnosis and treatment, vascular health research

Five teams of scientists earned research seed grants awarded this year by the John S. Dunn Foundation. The awards support new collaborations by researchers at Rice University's BioScience Research Collaborative (BRC) and their partners at other institutional members of the Gulf Coast Consortia (GCC).

26 Nov 2013

Biochemical signal in blood is associated with faster-progressing form of Parkinson's

The physical decline experienced by Parkinson's disease patients eventually leads to disability and a lower quality of life. Depending on the individual, the disorder can progress rapidly or slowly.

25 Nov 2013

Using radiation models to improve cancer therapies: an interview with Adrian Treverton, COO of Xstrahl and Jean-Pierre Wery, President of Crown Bioscience

What we are trying to do is take a cancer model like the PDX model (patient-derived tumor xenograft), which is a human-derived cancer growing in an in vivo model and apply radiation to that model.

From Xstrahl 20 Nov 2013

Researchers use computer modeling to investigate complex relationships between spread and evolution of HIV virus

Researchers at Los Alamos National Laboratory are investigating the complex relationships between the spread of the HIV virus in a population (epidemiology) and the actual, rapid evolution of the virus (phylogenetics) within each patient's body.

20 Nov 2013

New biomarker predicts that concussion victims may have cognitive dysfunction following mTBI

A new blood biomarker correctly predicted which concussion victims went on to have white matter tract structural damage and persistent cognitive dysfunction following a mild traumatic brain injury.

20 Nov 2013

Specific area of the brain linked to anxiety disorders in children and adolescents

Anxiety disorders are common in children and adolescents, affecting up to 25 percent of the youth population. Anxiety causes distress and functional impairment and, if left untreated, can result in bad grades, problems at home and increased rates of psychiatric disorders in adulthood.

20 Nov 2013

Research advances in search for biomarkers that may predict lung cancer

The professor of the Faculty of Medicine and Dentistry of the University of Valencia Carlos Camps has participated in a research that advances in the search for biomarkers that may predict lung cancer.

19 Nov 2013

Researchers create new statistical tools to find clues about cancer from raw data

Researchers at Rice University, Baylor College of Medicine (BCM) and the University of Texas at Austin are working together to create new statistical tools that can find clues about cancer that are hidden like needles in enormous haystacks of raw data.

15 Nov 2013

Global Genomics Group, Metabolon partner to discover novel targets for cardiovascular diseases

Global Genomics Group and Metabolon today announced that they have entered into a collaboration agreement to investigate biological networks and pathways in order to discover novel biomarkers and pharmaceutical targets for cardiovascular diseases.

15 Nov 2013

Biomarker News and Research

Further Reading

Scientists receive $4M grant to identify biomarker for secondary injuries associated with brain

Biohit Oyj to distribute Dynex automated ELISA systems with Gastropanel

VolitionRx's two-assay test can detect 85% of colorectal cancer, more than 50% of precancerous polyps

A new approach for treating colorectal cancer

Lexicon announces top-line results from initial Phase 2 study of LX1033 for treatment of IBS-d

IRCM researcher sheds light on inconsistencies between pharmacogenomic studies

New finding links obesity and high-fat, high-sugar diets with changes in inflammatory status

New biomarkers to improve diagnostics of prostate cancer

Researchers discover promising new approach for colorectal cancer treatment

New whitepaper examines main strategies employed to optimise target enrichment for NGS assays

Diagnosing colonic polyps: an interview with Dr. Haili Wang, Metabolomic Technologies Inc. (MTI)

Seed grants support cancer diagnosis and treatment, vascular health research

Biochemical signal in blood is associated with faster-progressing form of Parkinson's

Using radiation models to improve cancer therapies: an interview with Adrian Treverton, COO of Xstrahl and Jean-Pierre Wery, President of Crown Bioscience

Researchers use computer modeling to investigate complex relationships between spread and evolution of HIV virus

New biomarker predicts that concussion victims may have cognitive dysfunction following mTBI

Specific area of the brain linked to anxiety disorders in children and adolescents

Research advances in search for biomarkers that may predict lung cancer

Researchers create new statistical tools to find clues about cancer from raw data

Global Genomics Group, Metabolon partner to discover novel targets for cardiovascular diseases

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest Life Science News