Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Wnt5A signaling pathway helps researchers determine who may respond to BRAF inhibitors

One of the challenges of understanding cancer is trying to determine the mechanisms that drive metastasis, or the process by which tumor cells are able to spread throughout the body.

19 Oct 2013

Genalyte Gets Grant From NCI To Develop Biomarker Panel For Cancer

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18 Oct 2013

Genalyte receives NCI grant to develop biomarker panel to profile TAA autoantibodies

Genalyte, Inc., today announced that it has received a $1 million SBIR grant from the National Cancer Institute to develop a biomarker panel to profile tumor antigen-associated autoantibodies.

18 Oct 2013

Blood-Based Protein Test May Distinguish Between Malignant And Benign Lung Nodules

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17 Oct 2013

Jain Foundation Steps Up Efforts To Find Cure For Muscular Dystrophy

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17 Oct 2013

Celmatix presents six research findings at ASRM's annual meeting

Celmatix, a biotechnology company focused on helping physicians guide patients to treatments that maximize their personal reproductive potential, announced today six research presentations at the annual meeting of the American Society for Reproductive Medicine, being held October 12-17 in Boston.

17 Oct 2013

Proteins in CSF predict cognitive impairment before onset of disease

Johns Hopkins researchers say that by measuring levels of certain proteins in cerebrospinal fluid (CSF), they can predict when people will develop the cognitive impairment associated with Alzheimer's disease years before the first symptoms of memory loss appear.

17 Oct 2013

King's College researchers identify new biomarker that detects sepsis in blood

Researchers at King's College London have identified a biomarker - a biological 'fingerprint' - for sepsis in the blood, and showed it could be possible to diagnose the condition within two hours by screening for this biomarker at a patient's bedside.

17 Oct 2013

Jain Foundation Steps Up Efforts To Find Cure For Muscular Dystrophy

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16 Oct 2013

Simple blood test can help diagnose early-stage lung and prostate cancers

Early-stage lung and prostate cancers as well as their recurrence can be detected with a simple blood test, according to a study presented at the ANESTHESIOLOGY 2013 annual meeting.

16 Oct 2013

Tepnel Pharma Services uses Hologic’s Invader Plus technology to offer genotyping, CNV service

Tepnel Pharma Services, a division of Hologic, Inc., is now using Hologic’s proprietary Invader and Invader Plus technology as part of its Molecular Genetic Services offering, enabling it to offer customers a more cost effective and high throughput genotyping and copy number variation service.

From Hologic, Inc. 15 Oct 2013

Modeling, identifying predictors of Parkinson's disease with stem cells

The New York Stem Cell Foundation Research Institute has entered into a partnership with the Parkinson's Progression Markers Initiative to build resources for studying Parkinson's disease to accelerate new treatments. Sponsored by The Michael J. Fox Foundation for Parkinson's Research, PPMI is a landmark effort to identify and validate biomarkers of Parkinson's disease.

15 Oct 2013

New clinical trial shows increased asthma control with FeNO-guided anti-inflammatory treatment

A new randomised clinical trial shows lower incidence of asthma exacerbations and increased asthma control with Fractional exhaled Nitric Oxide (FeNO)-guided anti-inflammatory treatment.

11 Oct 2013

Research delves deeply into genomics of glioblastoma multiforme cases to better target disease

When The Cancer Genome Atlas launched its massively collaborative approach to organ-by-organ genomic analysis of cancers, the brain had both the benefit, and the challenge, of going first.

11 Oct 2013

Noninvasive tool created to detect pancreatic cancer through risk assessment test using saliva

Pancreatic cancer is one of the deadliest forms of cancer. Most of those with the disease will die within the first year of diagnosis, and just 6 percent will survive five years.

10 Oct 2013

Study associates high polyphenols intake with 30% reduction in mortality in older adults

It is the first time that a scientific study associates high polyphenols intake with a 30% reduction in mortality in older adults. The research, published on Journal of Nutrition, is the first to evaluate the total dietary polyphenol intake by using a nutritional biomarker and not only a food frequency questionnaire.

10 Oct 2013

Dry eye disease symptom change independent of tear osmolarity

Tear osmolarity is a poor indicator of treatment response in patients with dry eye disease (DED), suggests research published in the American Journal of Ophthalmology.

9 Oct 2013

Alnylam advances Development Candidate for ALN-AS1 for treatment of hepatic porphyrias

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, announced today that it is advancing its Development Candidate for ALN-AS1, an RNAi therapeutic targeting aminolevulinate synthase-1 (ALAS-1) for the treatment of hepatic porphyrias including acute intermittent porphyria (AIP).

9 Oct 2013

Personalised therapy can reduce risk of cardiac disease among diabetes patients

600,000 to 800,000 Austrians suffer from diabetes mellitus. Thanks to the biomarker known as NT-proBNP (a hormone specific to the heart), the sub-group of people who are at increased risk of cardiovascular disease can be determined even though their hearts appear to be healthy.

8 Oct 2013

Study discovers biomarker that helps doctors to accurately diagnose Parkinson's at earlier stage

Although Parkinson's disease is the second most prevalent neurodegenerative disorder in the U.S., there are no standard clinical tests available to identify this widespread condition.

8 Oct 2013

Biomarker News and Research

Further Reading

Wnt5A signaling pathway helps researchers determine who may respond to BRAF inhibitors

Genalyte Gets Grant From NCI To Develop Biomarker Panel For Cancer

Genalyte receives NCI grant to develop biomarker panel to profile TAA autoantibodies

Blood-Based Protein Test May Distinguish Between Malignant And Benign Lung Nodules

Jain Foundation Steps Up Efforts To Find Cure For Muscular Dystrophy

Celmatix presents six research findings at ASRM's annual meeting

Proteins in CSF predict cognitive impairment before onset of disease

King's College researchers identify new biomarker that detects sepsis in blood

Jain Foundation Steps Up Efforts To Find Cure For Muscular Dystrophy

Simple blood test can help diagnose early-stage lung and prostate cancers

Tepnel Pharma Services uses Hologic’s Invader Plus technology to offer genotyping, CNV service

Modeling, identifying predictors of Parkinson's disease with stem cells

New clinical trial shows increased asthma control with FeNO-guided anti-inflammatory treatment

Research delves deeply into genomics of glioblastoma multiforme cases to better target disease

Noninvasive tool created to detect pancreatic cancer through risk assessment test using saliva

Study associates high polyphenols intake with 30% reduction in mortality in older adults

Dry eye disease symptom change independent of tear osmolarity

Alnylam advances Development Candidate for ALN-AS1 for treatment of hepatic porphyrias

Personalised therapy can reduce risk of cardiac disease among diabetes patients

Study discovers biomarker that helps doctors to accurately diagnose Parkinson's at earlier stage

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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