Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Phosphoproteomic profiling reveals the complex interplay of immune cells in tumors

Researchers from the Icahn School of Medicine at Mount Sinai, in collaboration with the Clinical Proteomic Tumor Analysis Consortium of the National Institutes of Health, The University of Texas MD Anderson Cancer Center, Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, and others, have unveiled a detailed understanding of immune responses in cancer, marking a significant development in the field.

14 Feb 2024

Glial fibrillary acidic protein levels pinpoint future dementia risk a decade in advance

Researchers identify GFAP as a potent biomarker for predicting dementia risk over a decade before clinical diagnosis, underscoring its potential for early screening and intervention in asymptomatic individuals.

13 Feb 2024

Hand-held biosensor detects breast cancer biomarkers from saliva

Breast cancer is on the rise, but new tools for early detection could save lives.

13 Feb 2024

Combination therapy offers breakthrough in NSCLC treatment

A specific combination of targeted therapy and immunotherapy may better help patients with non-small cell lung cancer (NSCLC) overcome inherent immune resistance and reinvigorate anti-tumor activity, according to a new study led by a researcher from The University of Texas MD Anderson Cancer Center.

13 Feb 2024

Proteomic biomarkers in blood plasma as predictors of dementia in healthy individuals

The predictive power of plasma proteomic profiles for future dementia onset in adults without dementia.

13 Feb 2024

Mad2 expression levels with chromosomal abnormalities can be a biomarker for esophageal cancer

A new research paper was published in Oncotarget's Volume 15 on February 5, 2024, entitled, "Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples."

12 Feb 2024

IU researchers develop a breakthrough new blood test for schizophrenia

A team of researchers led by Indiana University School of Medicine faculty have developed a breakthrough new blood test for schizophrenia, a psychiatric disorder that includes hallucinations and delusions.

12 Feb 2024

New research shows promise for urine-based test to detect ovarian cancer

New research by Joseph Reiner and colleagues at Virginia Commonwealth University shows promise for a urine-based test for ovarian cancer. Reiner will present their research at the 68th Biophysical Society Annual Meeting, to be held February 10 - 14, 2024 in Philadelphia, Pennsylvania.

12 Feb 2024

Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

A new research paper was published in Genes & Cancer on February 5, 2023, entitled, "Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis."

9 Feb 2024

Multi-level network analysis provides integrated view of multiple sclerosis

International research led by the Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University, in collaboration with Hospital del Mar, Hospital Clínic, Charité - Medical University of Berlin, and the universities of Oslo and Genoa, has developed a computational biology tool, based on multi-level network analysis, to achieve an integrated vision of multiple sclerosis.

8 Feb 2024

Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "PROX1 interaction with α-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance."

8 Feb 2024

Enzyme released by immune cells may play role in depression

Mount Sinai researchers have shown for the first time that immune cells called monocytes, derived in the bone marrow and released into the bloodstream, can be drawn during stress into sites in the brain that control emotional behaviors.

8 Feb 2024

Study suggests there may be specific pathways to adolescent depression that begin in the womb

Researchers investigated the relationship between prenatal maternal inflammation (PNMI) and depressive symptoms in their adolescent offspring.

8 Feb 2024

Immune cell networks key to success of personalized cancer treatment

Through an analysis of tumor samples collected over time from patients with advanced melanoma, a Ludwig Cancer Research study has identified a set of preexisting conditions in tumors that predict whether such patients are likely to respond to a personalized immunotherapy known as adoptive T cell therapy (ACT) using tumor-infiltrating lymphocytes (TIL).

7 Feb 2024

New research facility at the University of Surrey could soon unlock the secrets of diseases

A new research facility at the University of Surrey could soon help society better understand various diseases or even help scientists trace nanoplastics through the bodies and cells of humans and animals.

5 Feb 2024

Long COVID and ME/CFS share isimilarities in immune system dysfunction, study finds

A study led by UMass Chan Medical School viral immunologists Liisa Selin, MD, PhD, and Anna Gil, PhD, discovered similarities in immune system dysfunction as a potential biomarker among people living with long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

1 Feb 2024

Biomarker News and Research

Further Reading

Phosphoproteomic profiling reveals the complex interplay of immune cells in tumors

Glial fibrillary acidic protein levels pinpoint future dementia risk a decade in advance

Hand-held biosensor detects breast cancer biomarkers from saliva

Combination therapy offers breakthrough in NSCLC treatment

Proteomic biomarkers in blood plasma as predictors of dementia in healthy individuals

Mad2 expression levels with chromosomal abnormalities can be a biomarker for esophageal cancer

IU researchers develop a breakthrough new blood test for schizophrenia

New research shows promise for urine-based test to detect ovarian cancer

Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

Multi-level network analysis provides integrated view of multiple sclerosis

Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

Enzyme released by immune cells may play role in depression

Study suggests there may be specific pathways to adolescent depression that begin in the womb

Immune cell networks key to success of personalized cancer treatment

New research facility at the University of Surrey could soon unlock the secrets of diseases

Long COVID and ME/CFS share isimilarities in immune system dysfunction, study finds

New approach offers hope for regaining lost memories in Alzheimer's

Berry consumption shown to lower stress-related disease risk in US adults

OMT could provide a viable, non-drug treatment for migraine headaches

Cadaveric pituitary-derived growth hormone delivery influences iatrogenic Alzheimer’s Disease

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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