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Insilico Medicine leverages AI to identify promising new target for breast and gynecological cancers

Insilico Medicine("Insilico"), a clinical stage generative artificial intelligence (AI)-driven drug discovery company, recently published an early research that it has identified MYT1 as a promising new therapeutic target for breast and gynecological cancer, and discovered a series of novel, potent, and highly selective inhibitors specifically targeting MYT1.

19 Jan 2024

Unveiling the cellular mechanisms of engram consolidation and memory refinement

Think of a time when you had two different but similar experiences in a short period. Maybe you attended two holiday parties in the same week or gave two presentations at work.

19 Jan 2024

StemSight and ERS Genomics focus on collaboration

License agreement provides StemSight access to CRISPR/Cas9 technology to be applied in development of cell therapies for corneal blindness.

17 Jan 2024

New USC study reveals how DNA loops silence gene activity

The blueprint for human life lies within the DNA in the nucleus of each of our cells. In human cells, around six and a half feet of this genetic material must be condensed to fit inside the nucleus. DNA condensation is not random.

16 Jan 2024

When mass spectrometry redefines the pharma industry

In this new episode of omg OMx, Kate Stumpo speaks to Bruker's Mike Greig about the incredible potential of mass spectrometry in pharma.

From Bruker Life Sciences Mass Spectrometry 12 Jan 2024

Scientists develop noninvasive way to monitor gene expression dynamics in the brain

Researchers introduced a non-invasive, sensitive method for monitoring gene expression in the brain using engineered reporters called released markers of activity, which can exit the brain into the blood for easy detection.

12 Jan 2024

New molecule targets key protein in autoimmune diseases

Scientists from Scripps Research have developed a small molecule that blocks the activity of a protein linked to autoimmune diseases, including systemic lupus erythematosus (SLE) and Crohn's disease.

11 Jan 2024

Revolutionary blood test monitors gene expression dynamics in the brain

The brain is the most protected organ in the body, sheathed in a complex and nearly impenetrable barrier of specialized blood vessels.

11 Jan 2024

New algorithm proves to be a powerful tool for detection and identification of novel bacterial organisms

Researchers developed the NOVA algorithm to systematically analyze bacterial isolates unidentified using traditional methods such as matrix-assisted laser desorption ionization-time of flight mass spectrometry and partial 16S rRNA gene sequencing using whole genome sequencing.

10 Jan 2024

"TimeMachine" algorithm revolutionizes circadian rhythm analysis with single blood sample

"TimeMachine," an algorithm developed by U.S. researchers, accurately predicts circadian phase from a single blood sample using gene expression, offering a novel, efficient approach to understanding circadian rhythms and their impact on health.

9 Jan 2024

New approach to Parkinson's treatment focuses on stopping toxic protein production

Like the Greek mythological beast with a snake's tail and two ferocious heads, a potential Parkinson's medicine created in the lab of chemist Matthew Disney, Ph.D., is also a type of chimera bearing two heads.

9 Jan 2024

Breakthrough in gene editing: Enhanced virus-like particles promise new era in genetic disease treatment

Researchers developed an advanced prime editor-engineered virus-like particle (PE-eVLP) system, significantly enhancing gene editing efficiency in human cells and showing potential for treating genetic diseases.

9 Jan 2024

BCG vaccine's impact on innate immunity explained at cellular level

Bacillus Calmette-Guérin (BCG) is one of the world’s oldest and most widely used vaccines. It was developed in the early 20th century to provide protection from tuberculosis.

9 Jan 2024

The equity imperative: A roundtable on transforming healthcare

In the Roundtable titled "A Glimpse at How Stakeholders Are Working Towards Achieving Health Equity," published in the peer-reviewed journal Health Equity, two expert panel discussions examine efforts to achieve maternal health equity and changes that health systems can make to operationalize health equity.

9 Jan 2024

Disease-causing bacteria use molecular "barcode" to distinguish between beneficial and toxic molecules

Researchers at McMaster University have discovered a molecular "barcode" system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.

8 Jan 2024

Engineered virus-like particles power up gene editing, correcting blindness in mice

Prime editing, a versatile form of gene editing that can correct most known disease-causing genetic mutations, now has a new vehicle to deliver its machinery into cells in living animals.

8 Jan 2024

Metabolically armored CAR-T cells demonstrate lasting efficacy against solid tumors

At EPFL's School of Engineering, Professor Li Tang's Laboratory of Biomaterials for Immunoengineering has made significant strides in cancer treatment research.

4 Jan 2024

Revolutionary RNA-based switch offers new control over gene expression in mammalian cells

Researchers developed an RNA-based switch, the pA regulator system, to control gene expression in mammalian cells by modulating synthetic polyA signal cleavage, offering a novel approach for gene therapy applications.

4 Jan 2024

Unmasking the persistent threats of long-COVID's pulmonary sequelae

A collaborative study led by Dr. Estefanía Nova-Lamperti of the Universidad de Concepción, Dr. Gonzalo Labarca of Harvard University, and Mauricio Hernández, of MELISA Institute, and which included the participation of researchers from leading academic institutions, sought to identify the sequelae associated with long-term pulmonary dysfunction (L-PDD) in patients with COVID-19.

4 Jan 2024

Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection

An atomic-level investigation of how Eastern equine encephalitis virus binds to a key receptor and gets inside of cells also has enabled the discovery of a decoy molecule that protects against the potentially deadly brain infection, in mice.

3 Jan 2024

Biotechnology News and Research

Insilico Medicine leverages AI to identify promising new target for breast and gynecological cancers

Unveiling the cellular mechanisms of engram consolidation and memory refinement

StemSight and ERS Genomics focus on collaboration

New USC study reveals how DNA loops silence gene activity

When mass spectrometry redefines the pharma industry

Scientists develop noninvasive way to monitor gene expression dynamics in the brain

New molecule targets key protein in autoimmune diseases

Revolutionary blood test monitors gene expression dynamics in the brain

New algorithm proves to be a powerful tool for detection and identification of novel bacterial organisms

"TimeMachine" algorithm revolutionizes circadian rhythm analysis with single blood sample

New approach to Parkinson's treatment focuses on stopping toxic protein production

Breakthrough in gene editing: Enhanced virus-like particles promise new era in genetic disease treatment

BCG vaccine's impact on innate immunity explained at cellular level

The equity imperative: A roundtable on transforming healthcare

Disease-causing bacteria use molecular "barcode" to distinguish between beneficial and toxic molecules

Engineered virus-like particles power up gene editing, correcting blindness in mice

Metabolically armored CAR-T cells demonstrate lasting efficacy against solid tumors

Revolutionary RNA-based switch offers new control over gene expression in mammalian cells

Unmasking the persistent threats of long-COVID's pulmonary sequelae

Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection

Biotechnology eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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