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Non-invasive brain stimulation techniques improve memory

Non-invasive brain stimulation techniques improve memory

Non-invasive brain stimulation techniques aimed at mental and neurological conditions include transcranial magnetic stimulation for depression, and transcranial direct current (electrical) stimulation, shown to improve memory. [More]
Viewpoints: When a doctor should keep quiet; 2 views of hospital pricing; Stem cell 'snake oil'

Viewpoints: When a doctor should keep quiet; 2 views of hospital pricing; Stem cell 'snake oil'

In medical school, we were taught not to withhold information from our patients or to be "paternal" in making decisions for them. We internalized the idea that fully informed patients are better equipped to make treatment decisions. [More]
Metal-on-metal hip implants cause inflammation of joint lining long before symptoms appear

Metal-on-metal hip implants cause inflammation of joint lining long before symptoms appear

Metal-on-metal hip implants can cause inflammation of the joint lining (synovitis) long before symptoms appear, and magnetic resonance imaging (MRI) can be used to identify this inflammation, according to a new study by researchers at Hospital for Special Surgery. The study, which appears in an upcoming issue of the Journal of Bone & Joint Surgery, demonstrates that MRI can be used to identify implants that are going to fail before people become symptomatic. [More]
People diagnosed with cancer are more likely to declare bankruptcy

People diagnosed with cancer are more likely to declare bankruptcy

People diagnosed with cancer are more than two-and-a-half times more likely to declare bankruptcy than those without cancer, according to a new study from Fred Hutchinson Cancer Research Center. Researchers also found that younger cancer patients had two- to five-fold higher bankruptcy rates compared to older patients, and that overall bankruptcy filings increased as time passed following diagnosis. [More]

Cedars-Sinai launches new clinical trial to study effects of cabozantinib in prostate cancer patients

Researchers at Cedars-Sinai have launched a new clinical trial to investigate the effects of a cancer-fighting drug therapy that has shown favorable outcomes in patients with advanced metastatic prostate cancer. [More]
Study reveals that prolonged Dkk1 signaling can lead to fibrosis, stiffening of artery walls

Study reveals that prolonged Dkk1 signaling can lead to fibrosis, stiffening of artery walls

The hardening of arteries is a hallmark of atherosclerosis, an often deadly disease in which plaques, excessive connective tissue, and other changes build up inside vessel walls and squeeze off the flow of oxygen-rich blood throughout the body. [More]
LMU researchers reveal link between natural killer cells and hematopoiesis

LMU researchers reveal link between natural killer cells and hematopoiesis

Infections can trigger hematopoiesis at sites outside the bone marrow - in the liver, the spleen or the skin. Researchers at Ludwig-Maximilians-Universitaet in Munich now show that a specific type of immune cell facilitates such "extra medullary" formation of blood cells. [More]
Bayer HealthCare to present new data on oncology portfolio at ASCO meeting

Bayer HealthCare to present new data on oncology portfolio at ASCO meeting

Bayer HealthCare announced today that new data on the oncology portfolio, including Nexavar (sorafenib) tablets, Stivarga (regorafenib) tablets and the recently U.S. Food and Drug Administration approved product Xofigo (radium Ra 223 dichloride) injection will be presented at the 49th Annual Meeting of the American Society of Clinical Oncology, May 31 – June 4, in Chicago, IL (USA). [More]

GE Healthcare introduces novel MR imaging technology

At an event held today at Hospital for Special Surgery, GE Healthcare introduced MAVRIC SL, a novel magnetic resonance imaging technique designed to address the growing clinical need to more accurately image soft tissue and bone in patients with MR Conditional-labeled implants, such as joint replacements and other instrumentation. [More]

Prostate cancer drug Xofigo gets FDA approval

The U.S. Food and Drug Administration today approved Xofigo (radium Ra 223 dichloride) to treat men with symptomatic late-stage (metastatic) castration-resistant prostate cancer that has spread to bones but not to other organs. [More]
Sanofi, Regeneron enroll patients in two sarilumab Phase 3 trials for treatment of RA

Sanofi, Regeneron enroll patients in two sarilumab Phase 3 trials for treatment of RA

Sanofi and Regeneron Pharmaceuticals, Inc. today announced that the COMPARE and ASCERTAIN trials of sarilumab, the first fully human monoclonal antibody directed against the IL-6 receptor, which is delivered by subcutaneous injection every other week, have enrolled their first patients. [More]

A growing number of patients learn of allergies only after surgery is done

Imagine what Paula Spurlock must have been going through. Shortly after having a hip replaced in 2011, the trouble started. "I had horrible itching, really bad migraines and intense pain throughout my body," she said. "I couldn't take it. Every single thing in me itched." [More]
New study reveals another duet played by Notch and BMP signals

New study reveals another duet played by Notch and BMP signals

A small ensemble of musicians can produce an infinite number of melodies, harmonies and rhythms. So too, do a handful of workhorse signaling pathways that interact to construct multiple structures that comprise the vertebrate body. [More]

Prostate cancer patients need to be aware of the effects of androgen deprivation therapy

Androgen deprivation therapy is a common and effective treatment for advanced prostate cancer. However, among other side-effects, it can cause significant bone thinning in men on long-term treatment. [More]
Researchers uncover unique cellular, molecular mechanisms behind tooth renewal

Researchers uncover unique cellular, molecular mechanisms behind tooth renewal

Alligators may help scientists learn how to stimulate tooth regeneration in people, according to new research led by the Keck School of Medicine of the University of Southern California. [More]
Better understanding of cells' development has implications in study of inflammatory diseases

Better understanding of cells' development has implications in study of inflammatory diseases

Labs around the world, and a core group at Penn, have been studying recently described populations of immune cells called innate lymphoid cells. Some researchers liken them to foot soldiers that protect boundary tissues such as the skin, the lining of the lung, and the lining of the gut from microbial onslaught. They also have shown they play a role in inflammatory disease, when the body's immune system is too active. [More]
Synthetic silicate nanoplatelets can stimulate stem cells to become bone cells

Synthetic silicate nanoplatelets can stimulate stem cells to become bone cells

In new research published online May 13, 2013 in Advanced Materials, researchers from Brigham and Women's Hospital are the first to report that synthetic silicate nanoplatelets (also known as layered clay) can induce stem cells to become bone cells without the need of additional bone-inducing factors. [More]

Misaligned teeth are chief culprits in the development of gum disease, tooth decay

Crooked, crowded teeth can rob you of your health. In fact, misaligned teeth are among the chief culprits in the development of gum disease and tooth decay. [More]
NCCC doctors find effective drug combination to treat chronic lymphocytic leukemia

NCCC doctors find effective drug combination to treat chronic lymphocytic leukemia

Doctors at Dartmouth-Hitchcock's Norris Cotton Cancer Center have found a combination of drugs to potentially treat chronic lymphocytic leukemia more effectively. [More]
Researchers identify microRNA-155 as prognostic marker, treatment target in patients with AML

Researchers identify microRNA-155 as prognostic marker, treatment target in patients with AML

A study has identified microRNA-155 as a new independent prognostic marker and treatment target in patients with acute myeloid leukemia that has normal-looking chromosomes under the microscope (that is, cytogenetically normal acute myeloid leukemia, or CN-AML). [More]