Bone News and Research RSS Feed - Bone News and Research

Testosterone may lead to greater heart attack risk in men than women

Testosterone may lead to greater heart attack risk in men than women

Testosterone might be involved in explaining why men have a greater risk of heart attacks than women of similar age, according to a study funded by the British Heart Foundation and the Biotechnology and Biological Sciences Research Council. The findings, published in the journal Scientific Reports, could lead to new therapies to help reduce heart attack risk. [More]
Gladstone scientists bioengineer micro-scale heart tissues from stem cells

Gladstone scientists bioengineer micro-scale heart tissues from stem cells

Scientists at the Gladstone Institutes have invented a new way to create three-dimensional human heart tissue from stem cells. The tissue can be used to model disease and test drugs, and it opens the door for a precision medicine approach to treating heart disease. Although there are existing techniques to make three-dimensional tissues from heart cells, the new method dramatically reduces the number of cells needed, making it an easier, cheaper, and more efficient system. [More]
Low levels of 25-hydroxyvitamin D highly prevalent among children with type 1 diabetes

Low levels of 25-hydroxyvitamin D highly prevalent among children with type 1 diabetes

During the past two decades, vitamin D status, defined as serum concentration of 25-hydroxyvitamin D, has emerged as a predictor of key clinical outcomes including bone health, glucose metabolism, cardiovascular health, immune health and survival. [More]
Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Adolescents and young adults with a severe inherited immunodeficiency disorder improved following treatment with novel gene therapy developed at St. Jude Children's Research Hospital and at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. The results of this study appear today in the journal Science Translational Medicine. [More]
Orthocell announces further validation of 'Cell Factory' concept for generation of bone, cartilage

Orthocell announces further validation of 'Cell Factory' concept for generation of bone, cartilage

Regenerative medicine company Orthocell Limited is pleased to announce further validation of ‘Cell Factory’ concepts for generating tissue specific growth factors and protein’s to aid in the healing and regeneration of bone, tendon and cartilage. [More]
Endurance running training increases bone density

Endurance running training increases bone density

Spanish researchers have analysed the effect of endurance running training on the stiffness index, a variable that is directly related to bone quality. The results confirm that the greater the race distance that is trained, the better; this can be used, therefore, to prevent the progressive decline in bone mineral density that occurs with age. [More]
Inhibiting adrenaline receptors reduces breast cancer brain metastases

Inhibiting adrenaline receptors reduces breast cancer brain metastases

While we look to invent new medicines to treat cancer, a parallel approach to repurpose existing medicines may be highly effective. Stress, mediated by adrenaline, has been suspected to promote cancer growth and this research study shows that by blocking adrenaline receptors in breast cancers, they are less successful in spreading to and growing in the brain. [More]
Professor outlines effects of sports-specific counseling on injury outcomes in youth athletes

Professor outlines effects of sports-specific counseling on injury outcomes in youth athletes

Neeru Jayanthi, MD, Associate Professor of Orthopedics and Sports Medicine at Emory University Sports Medicine Center in Atlanta, GA, presented "The Effects of Serial Sports Training Risk Assessment and Counseling in Kids (T.R.A.C.K.)" at the 25th Annual Meeting of the American Medical Society for Sports Medicine in Dallas, TX. [More]
Medi-551 antibody treatment decreases number of cancer stem cells by half in multiple myeloma patients

Medi-551 antibody treatment decreases number of cancer stem cells by half in multiple myeloma patients

An experimental antibody treatment decreased by half the number of cancer stem cells that drive the growth of tumors in nearly all patients with multiple myeloma, a cancer of the bone marrow and bone tissue, according to results of a preliminary clinical trial led by Johns Hopkins Kimmel Cancer Center scientists. [More]
Investigators find tacrolimus to be very effective in reducing ocular symptoms of GVHD

Investigators find tacrolimus to be very effective in reducing ocular symptoms of GVHD

Researchers from Massachusetts Eye and Ear/Harvard Medical School have conducted a clinical trial comparing the safety and efficacy of topical tacrolimus, an immunosuppressive therapy, and topical methylprednisolone, a steroid medication, in patients with ocular graft-versus-host-disease (GVHD) -- a complication associated with allogeneic bone marrow transplants in which the transplanted immune system's cells attack certain parts of the recipient's body, including the cornea and ocular surface. [More]
Inflammation after stroke may help the brain to self-repair

Inflammation after stroke may help the brain to self-repair

After a stroke, there is inflammation in the damaged part of the brain. Until now, the inflammation has been seen as a negative consequence that needs to be abolished as soon as possible. But, as it turns out, there are also some positive sides to the inflammation, and it can actually help the brain to self-repair. [More]
Palovarotene drug may prevent multiple musculoskeletal problems linked with FOP

Palovarotene drug may prevent multiple musculoskeletal problems linked with FOP

New research in laboratory animals suggests that the drug palovarotene may prevent multiple skeletal problems caused by a rare but extremely disabling genetic bone disease, and may even be a candidate for use in newborn babies with the condition. [More]
Pluristem granted two key cell therapy patents in Japan

Pluristem granted two key cell therapy patents in Japan

Pluristem Therapeutics Inc. (PSTI), a leading developer of placenta-based cell therapy products, has announced that the Japan Patent Office has granted the Company two key patents addressing... [More]
Scientists use FAN1 knockout mice to refine detailed mechanisms involved in damaged DNA repair

Scientists use FAN1 knockout mice to refine detailed mechanisms involved in damaged DNA repair

Like jewels in a vault, our precious genetic material is stored in the nucleus of a cell--sequestered away from potentially damaging cellular components and toxins so that no harm can come to it. Yet over the course of a life moving through this world, our DNA does get damaged, and our cells have a host of complicated repair mechanisms to deal with such injuries. [More]
Study assesses risk factors for metastases in prostate cancer patients on active surveillance

Study assesses risk factors for metastases in prostate cancer patients on active surveillance

Radical treatment such as surgery and radiation for localized prostate cancer may cause significant side effects. Active surveillance is increasingly accepted as an option for treating patients with clinically insignificant disease to maintain their quality of life. [More]
Increased BMP7 levels predict PAH mortality

Increased BMP7 levels predict PAH mortality

Elevated levels of circulating bone morphogenetic protein 7 are associated with an increased mortality risk in patients with pulmonary arterial hypertension, find Chinese researchers. [More]
BMPR2 mutations affect outcomes of PAH patients

BMPR2 mutations affect outcomes of PAH patients

Mutations in the bone morphogenetic protein receptor type II gene affect not only the risk of developing pulmonary arterial hypertension but also the severity and outcomes of the disease, shows a meta-analysis of individual patient data. [More]
Substances from tequila plant may help treat osteoporosis

Substances from tequila plant may help treat osteoporosis

Mexican scientist identified substances from the plant that enhance absorption of calcium in the body. [More]
Resuscitation drugs along with defibrillation shocks can help stabilize heart beat after cardiac arrest

Resuscitation drugs along with defibrillation shocks can help stabilize heart beat after cardiac arrest

Administering heart resuscitation drugs to patients whose cardiac arrest is witnessed at the time of the attack can improve survival, but needs to be done through an IV line rather than directly into bone marrow as is more commonly done by paramedics, a new study involving UT Southwestern Medical Center emergency physicians and Dallas-Fort Worth Emergency Medical Services agencies reveals. [More]
Antimicrobial silicon nitride holds promise as therapeutic aid for treating periodontitis

Antimicrobial silicon nitride holds promise as therapeutic aid for treating periodontitis

Severe gum disease known as periodontitis can lead to tooth loss, and treating it remains a challenge. But new approaches involving silicon nitride, a ceramic material used in spinal implants, could be on the way. The surface of silicon nitride has a lethal effect on the bacteria that commonly cause periodontitis. Now scientists, reporting in ACS' journal Langmuir, are examining why this happens. Their findings could help inform future efforts to treat the disease. [More]
Advertisement
Advertisement