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Next-gen BTK degrader could help overcome treatment resistance in chronic lymphocytic leukemia

New research from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations has identified a next-generation BTK degrader that could help overcome treatment resistance in chronic lymphocytic leukemia (CLL) and related blood cancers.

1 Feb 2024

CRISPR revolutionized: New method edits genes directly in the body

Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic on cells removed from the body, after which the edited cells are returned to the patient.

1 Feb 2024

Is there an association between vitamin D, immunocompetence, and aging?

The role of an individual’s immunocompetence in the responsiveness to vitamin D.

1 Feb 2024

Surge in syphilis cases leads some providers to ration penicillin

When Stephen Miller left his primary care practice to work in public health a little under two years ago, he said, he was shocked by how many cases of syphilis the clinic was treating.

1 Feb 2024

Scientists regenerate fully functional urinary bladder tissue using a non-human primate model

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University succeeded in regenerating fully functional urinary bladder tissue in a long-term study utilizing a non-human primate model.

30 Jan 2024

Vegan and keto diets trigger distinct immune system changes in just two weeks

Researchers at the National Institutes of Health observed rapid and distinct immune system changes in a small study of people who switched to a vegan or a ketogenic (also called keto) diet.

30 Jan 2024

Overcoming stigma to start early conversations about cognitive decline

Approximately four of five primary care clinicians consider themselves on the front lines of brain health.

30 Jan 2024

RNA sequencing analysis feasible for diagnosis of molecular subtypes in pediatric B-ALL

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, representing more than 30% of all pediatric cases.

29 Jan 2024

European scientists target high-risk childhood cancer with liquid biopsy

Neuroblastoma mainly affects toddlers and young children - in the EU region there are 1500 new cases per year.

29 Jan 2024

Dr. Chao Ma: Pioneering 'Leukemia-on-a-Chip' for CAR T Cell Therapy at SLAS 2024

NewsMedical speaks with Chao Ma, Ph.D. a Research Assistant Professor at New York University Tandon School of Engineering, ahead of his presentation at SLAS 2024.

From Society for Laboratory Automation and Screening (SLAS) 29 Jan 2024

Gene activity plays key role in immune cell production, study shows

As people age or become ill, their immune systems can become exhausted and less capable of fighting off viruses such as the flu or COVID-19.

27 Jan 2024

Sclerostin may protect against heart disease in patients with type 2 diabetes

A study carried out by the MP20-Biomarkers of Metabolic and Bone Diseases research group at the Biohealth Research Institute in Granada (ibs.GRANADA), led by UGR Professor Manuel Muñoz Torres, has provided significant insights into the role of sclerostin in protecting against atherosclerosis in patients with type 2 diabetes.

26 Jan 2024

The association between handgrip strength and functional outcomes in long COVID-19

The association between dynapenia with long coronavirus disease 2019 (COVID-19).

26 Jan 2024

Ancient Brazilian genomes may hold the secrets of treponemal evolutionary history

Study reconstructs four ancient treponeme genomes from 2,000-year-old Brazilian remains, revealing their close relation to the bejel-causing Treponema pallidum endemicum and challenging previous hypotheses about treponeme subspecies adaptability.

25 Jan 2024

Study links heavy metals to depleted ovarian reserves

Middle-aged women with elevated levels of heavy metals are more likely to have depleted ovarian function and egg reserves, which may lead to earlier arrival of menopause and its negative health effects, a new University of Michigan study shows.

25 Jan 2024

Widespread exposure to toxic metals linked with earlier aging of the ovaries in middle-aged women

Middle-aged women who are exposed to toxic metals may have fewer eggs in their ovaries as they approach menopause, according to new research published in The Journal of Clinical Endocrinology & Metabolism.

25 Jan 2024

Unbiased assessment of vamorolone for treating Duchenne muscular dystrophy

The drug vamorolone (Agamree) has been hailed as a promising new drug to treat Duchenne muscular dystrophy (DMD).

25 Jan 2024

New study reveals optimal drug sequencing for postmenopausal osteoporosis treatment

The effectiveness and safety of available sequential treatments for the long-term management of postmenopausal osteoporosis.

25 Jan 2024

Penn analysis shows low risk of secondary cancers following CAR T cell therapy

The development of any type of second cancer following CAR T cell therapy is a rare occurrence, as found in an analysis of more than 400 patients treated at Penn Medicine, researchers from the Perelman School of Medicine at the University of Pennsylvania reported today in Nature Medicine.

24 Jan 2024

Novel macrolide- DEL-1 axis helps in bone regeneration and new bone formation

Periodontitis is characterized by the loss of teeth resulting from inflammation of gums due to bacterial infections.

24 Jan 2024

Bone News and Research

Next-gen BTK degrader could help overcome treatment resistance in chronic lymphocytic leukemia

CRISPR revolutionized: New method edits genes directly in the body

Is there an association between vitamin D, immunocompetence, and aging?

Surge in syphilis cases leads some providers to ration penicillin

Scientists regenerate fully functional urinary bladder tissue using a non-human primate model

Vegan and keto diets trigger distinct immune system changes in just two weeks

Overcoming stigma to start early conversations about cognitive decline

RNA sequencing analysis feasible for diagnosis of molecular subtypes in pediatric B-ALL

European scientists target high-risk childhood cancer with liquid biopsy

Dr. Chao Ma: Pioneering 'Leukemia-on-a-Chip' for CAR T Cell Therapy at SLAS 2024

Gene activity plays key role in immune cell production, study shows

Sclerostin may protect against heart disease in patients with type 2 diabetes

The association between handgrip strength and functional outcomes in long COVID-19

Ancient Brazilian genomes may hold the secrets of treponemal evolutionary history

Study links heavy metals to depleted ovarian reserves

Widespread exposure to toxic metals linked with earlier aging of the ovaries in middle-aged women

Unbiased assessment of vamorolone for treating Duchenne muscular dystrophy

New study reveals optimal drug sequencing for postmenopausal osteoporosis treatment

Penn analysis shows low risk of secondary cancers following CAR T cell therapy

Novel macrolide- DEL-1 axis helps in bone regeneration and new bone formation

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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