Carcinomas News and Research

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Researchers report decline in cancer diagnoses due to COVID-19 crisis

Cancer care has dramatically changed as a result of the measures taken during the COVID-19 pandemic: many patients have not been going to their GPs, or putting it off, and have been referred to the hospital later.

11 May 2020

Patients with aggressive form of skin cancer can benefit from new type of immunotherapy

In what is believed to be a first-of-its-kind study to evaluate the safety of a type of immunotherapy before surgery in patients with an aggressive form of skin cancer, researchers report that the treatment eliminated pathologic evidence of cancer in nearly half of the study participants undergoing surgery.

27 Apr 2020

Overexpression of hPCL3S could contribute to tumor progression in prostate cancer

The cover for issue 12 of Oncotarget features Figure 11, "Global analyses of the RNA-Seq data of LNCaP empty vector and LNCaP cells overexpressing hPCL3S (Clone 12)" by Abdelfettah, et al.

25 Mar 2020

UArizona receives $6.9 million grant to make advances in skin cancer prevention and treatment

Skin cancer is the most common malignancy worldwide, and one in three new cancers diagnosed is a form of skin cancer, according to the Skin Cancer Foundation. This amounts to about 5 million non-melanoma skin cancers in the United States each year.

6 Feb 2020

RNA affecting skin cancer progression discovered

Researchers at the University of Turku, Turku University Central Hospital, and Western Cancer Center have discovered a new RNA molecule, PRECSIT, which regulates the growth and invasion of squamous cell carcinoma of the skin.

4 Feb 2020

Study looks into the virome of early stage, p16-positive OPSCC and neck metastasis

In this prospective study, a pan-pathogen microarray was used to determine the virome of early stage, p16-positive OPSCC and neck metastasis treated with transoral robotic surgery and neck dissection.

27 Jan 2020

Scientists discover new drug target for prostate cancer in the non-coding genome

Scientists at Princess Margaret Cancer Centre have identified the drivers of a crucial gene involved in prostate cancer, revealing new targets for drug design.

23 Jan 2020

Scientists discover how B-cells in tumor cells promote a favorable immunotherapy response

The white blood cells are potent fighters that protect the body against foreign invaders, including pathogens and cancer cells. Scientists have found that the presence of B cells, which are powerhouses, in tumor cells, combat the disease from within.

16 Jan 2020

B cell count tells how certain cancers will respond to immunotherapy

Some melanomas, sarcomas and renal cell carcinomas, but not all, have been found to respond dramatically to new drugs called immune checkpoint blockers, which exploit the body’s known capability to mount an immune response against the foreign antigen-bearing tumor cells.

15 Jan 2020

Number of operations performed in a hospital linked to success of cancer surgery

Tumors of the colon, so-called colorectal carcinomas, are the second to third most frequent tumors in women and men in Germany. The surgical removal of the tumors is a central component of the therapy.

14 Jan 2020

Cornell study details role of stem cell in deadly gastric cancer

A Cornell study provides important new insights into a common and deadly type of gastric cancer.

7 Jan 2020

New antibody-drug conjugate shows promising activity in salivary gland tumors

The antibody-drug conjugate ado-trastuzumab emtansine (T-DM1) has promising activity in HER2 amplified salivary gland tumors, according to data published in the Annals of Oncology.

7 Jan 2020

Synthetic mRNA nanoparticles restore tumor suppressor gene, make cancer cells susceptible to drugs

In preclinical experiments, investigators restored p53 using synthetic mRNA nanoparticles, making lung and liver cancer cells susceptible to available cancer drugs.

23 Dec 2019

Study reveals new role for a triple-negative breast cancer target

Unlike almost every other organ, the mammary gland does not develop until after birth. And it's unusually dynamic, shape-shifting during menstrual cycles, puberty, pregnancy, and lactation.

19 Dec 2019

Targeting specific nuclear transport systems may lead to possible therapeutic strategies for cancer

Although less often the focus of cancer research, recent studies have hinted at the possible importance of a type of protein known as nuclear transport receptors.

17 Dec 2019

Rice University study aims to clarify microscopic aspects of cancer initiation

When do cancer-prone cells turn into full-blown cancer? A Rice University scientist and his colleague believe there's a way to know.

12 Dec 2019

ACCC project develops resources to support treatment of patients with cutaneous squamous cell carcinoma

Due to the rarity of advanced cutaneous squamous cell carcinoma (cSCC), staying current with the latest information on diagnosing, treating, and supporting patients with this diagnosis can be challenging for clinicians who do not often encounter advanced cSCC in practice.

4 Dec 2019