Cardiomyopathy News and Research

RSS

Cardiomyopathy is a group of diseases with primary, usually diffuse, involvement of the myocardium. The myocardial disease is not secondary to ischaemic, valvular, congenital or pericardial disease.

Earlier screening for rare genetic mutation could lead to faster treatment for heart failure in Black Americans

Researchers have linked a rare genetic mutation found mostly in Black Americans and other people of African descent to an earlier onset of heart failure and a higher risk of hospitalization.

8 Dec 2021

Heart failure patients may benefit from common type 2 diabetes drug

Dapagliflozin, a drug commonly used to treat type 2 diabetes, improved symptoms and physical limitations in patients with heart failure with preserved ejection fraction, according to clinical trial results published in Nature Medicine.

29 Nov 2021

Drug improved cardiac structure and function in patients with early-stage hypertrophic cardiomyopathy

Valsartan, an angiotensin II receptor blocker drug, delayed disease progression and improved cardiac structure and function in patients with early-stage hypertrophic cardiomyopathy, according to results from a recent clinical trial published in Nature Medicine.

16 Nov 2021

Type 2 diabetes medication works effectively, safely in patients hospitalized for acute heart failure

Adults treated with empagliflozin during hospitalization for acute heart failure experienced a clinical benefit such as increased survival, lower risk of heart failure hospital readmission and an overall improvement in their quality of life, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2021.

15 Nov 2021

Trial finds similar five-year outcomes with transcatheter or surgical aortic valve replacement

New five-year data from the SURTAVI trial found that there was no difference in all-cause mortality or stroke between patients at intermediate surgical risk who had transcatheter aortic valve replacement (TAVR) or surgery.

8 Nov 2021

Experts gain insights into pathomechanisms of dilated cardiomyopathy

Titin is a "titanically large" protein – the largest in the human body – which enables elastic movements of our muscles, including the heart.

6 Nov 2021

New machine-learning model can identify individuals at risk of rare cardiomyopathy

A machine-learning model can identify patients at risk of a rare cardiomyopathy, according to a study published in Nature Communications.

11 Oct 2021

CDC and ClinGen partner to develop expert curated variant list for the genomic community

The Centers for Disease Control and Prevention's Genetic Testing Reference Material Program (GeT-RM) has partnered with the Clinical Genome Resource (ClinGen) to develop a publicly available list of 546 expert curated pathogenic variants in 84 genes for use in next-generation sequencing (NGS) genetic testing.

11 Oct 2021

Researchers develop efficient approach to identify 3D features of post-infarction scarring

A multidisciplinary team of scientists based at the Universidad de Valladolid and the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has developed a highly efficient method for identifying the 3-dimensional features of the scar tissue formed after a myocardial infarction.

28 Sep 2021

Breast radiation after lumpectomy decreases incidence of ipsilateral breast recurrence for 'low risk' DCIS

A long-term follow up analysis of the NRG-RTOG 9804 randomized trial has shown that breast radiation following lumpectomy significantly reduces incidence of ipsilateral breast recurrence (IBR) for "low risk" DCIS.

27 Sep 2021

New guidelines for improving maternal cardiovascular health before, during and after pregnancy

Thanks largely to the efforts of Johns Hopkins Medicine researchers, the American Heart Association recently announced recommendations for improving cardiovascular health outcomes in women before, during and after pregnancy.

24 Sep 2021

Early treatment with ACE inhibitors improves cardiac outcomes of patients with Becker muscular dystrophy

There is no consensus on when to introduce cardioprotective treatment in patients with Becker muscular dystrophy (BMD), and practice varies widely.

20 Sep 2021

New AI technology for heart imaging could improve care for patients

A new artificial-intelligence technology for heart imaging can potentially improve care for patients, allowing doctors to examine their hearts for scar tissue while eliminating the need for contrast injections required for traditional cardiovascular magnetic resonance imaging (CMR).

1 Sep 2021

Genomic autopsy reveals many genetic variants associated with cardiomyopathy

Postmortem genetic testing, or genomic autopsy, of young individuals who experienced sudden death revealed many had known genetic variants that are associated with cardiomyopathy, according to a Northwestern Medicine study published in JAMA Cardiology.

31 Aug 2021

Molecular autopsy of dried blood spots can identify underlying cause of sudden cardiac death in a young person

The underlying cause of sudden cardiac death (SCD) in a young person is often difficult to identify. A genetic analysis could provide more information in many cases, but blood samples are not collected routinely at the time of death, and DNA extracted from the tissues collected at autopsy is damaged because of the way they are fixed in formalin and paraffin-embedded.

30 Aug 2021

AHA special issue focuses on health disparities among racial, ethnic communities

Poverty and Black race were associated with higher rates of lower leg amputation among people with peripheral artery disease who live in metropolitan areas, according to new research published today in a special issue of the Journal of the American Heart Association, an open access journal of the American Heart Association.

25 Aug 2021

Cardiomyopathy News and Research

Further Reading

Earlier screening for rare genetic mutation could lead to faster treatment for heart failure in Black Americans

Heart failure patients may benefit from common type 2 diabetes drug

Drug improved cardiac structure and function in patients with early-stage hypertrophic cardiomyopathy

Type 2 diabetes medication works effectively, safely in patients hospitalized for acute heart failure

Trial finds similar five-year outcomes with transcatheter or surgical aortic valve replacement

Experts gain insights into pathomechanisms of dilated cardiomyopathy

New machine-learning model can identify individuals at risk of rare cardiomyopathy

CDC and ClinGen partner to develop expert curated variant list for the genomic community

Researchers develop efficient approach to identify 3D features of post-infarction scarring

Breast radiation after lumpectomy decreases incidence of ipsilateral breast recurrence for 'low risk' DCIS

New guidelines for improving maternal cardiovascular health before, during and after pregnancy

Early treatment with ACE inhibitors improves cardiac outcomes of patients with Becker muscular dystrophy

New AI technology for heart imaging could improve care for patients

Genomic autopsy reveals many genetic variants associated with cardiomyopathy

Molecular autopsy of dried blood spots can identify underlying cause of sudden cardiac death in a young person

AHA special issue focuses on health disparities among racial, ethnic communities

PROFID project aims to personalize prevention of sudden cardiac death after myocardial infarction

New AHA statement provides guidance about cardiovascular genetic testing in children

Researchers recommend urgent adaptation plans to mitigate heat-related deaths and illnesses

Infantile sudden death associated with a de novo genetic mutation in the SOS1 gene

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest News