Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Positive data from Histogenics' NeoCart Phase 2 study on knee cartilage injury

Histogenics Corporation, a privately held regenerative medicine company, today announced the presentation of positive Phase 2 data for the NeoCart Autologous Cartilage Tissue Implant.

29 Jul 2011

Janssen receives FDA Complete Response letter for SIMPONI sBLA to treat RA

Janssen Biotech, Inc. announced today that the U.S. Food and Drug Administration (FDA) issued a Complete Response letter for its supplemental Biologics License Application (sBLA) for SIMPONI.

25 Jul 2011

Normal stem cell encourages growth of cancer stem cells and fuels ovarian cancer

Researchers at the University of Michigan Comprehensive Cancer Center have found that a type of normal stem cell fuels ovarian cancer by encouraging cancer stem cells to grow.

20 Jul 2011

Positive results from sarilumab Phase 2b trial on RA, ankylosing spondylitis

Sanofi and Regeneron Pharmaceuticals, Inc. announced results from Phase 2b trials in rheumatoid arthritis (RA) and ankylosing spondylitis (AS) with sarilumab, a novel, high-affinity, subcutaneously administered, fully-human antibody targeting the interleukin-6 receptor.

13 Jul 2011

Research validates SpinalCyte's core technology to regrow the spinal disc

SpinalCyte, LLC, a spinal technology company focused on autologous regrowth of the spinal disc nucleus using human dermal fibroblasts, announced today the publication of its research completed with Rice University, titled, "Chondrogenic Differentiation of Neonatal Human Dermal Fibroblasts Encapsulated in Alginate Beads with Hydrostatic Compression Under Hypoxic Conditions in the Presence of Bone Morphogenetic Protein-2".

11 Jul 2011

Arthroscopy as effective as open surgery for patients with common hip problem

Researchers at Hospital for Special Surgery have found that in comparison to open surgery, arthroscopic treatment of a common hip problem that leads to arthritis produces similar outcomes in terms of repairing structural problems in most patients.

11 Jul 2011

Patients with motion limitations after knee surgery more likely to develop osteoarthritis

The onset of osteoarthritis may be related to a loss of knee motion after reconstructive ACL surgery, as noted in new research presented at the American Orthopaedic Society for Sports Medicine's Annual Meeting in San Diego, California, July 7-10, 2011.

11 Jul 2011

Arthroscopy restores range of motion in patients with common hip problem

Arthroscopic treatment of a common hip problem that leads to arthritis is successful in terms of restoring range of motion, according to results from a recent Hospital for Special Surgery study.

11 Jul 2011

Gender may increase risk of cartilage lesions in ACL knee injury

Gender may be associated with an increased risk of cartilage lesions in anterior cruciate ligament (ACL) injured knees, according to research being presented at the American Orthopaedic Society for Sports Medicine's Annual Meeting in San Diego.

7 Jul 2011

Serum-free media with growth factors can improve MSCs' cell fate regulation

Mensenchymal stem cells (MSCs), multipotent cells identified in bone marrow and other tissues, have been shown to be therapeutically effective in the immunosuppression of T-cells, the regeneration of blood vessels, assisting in skin wound healing, and suppressing chronic airway inflammation in some asthma cases.

30 Jun 2011

Scil Technology receives public research grant for novel rheumatoid arthritis treatments

Scil Technology GmbH, a biopharmaceutical company with core expertise in protein drug development, formulation and analytics, today announced that it has been awarded research funding by the German Federal Ministry of Education and Research (BMBF) under BMBF’s KMU-innovativ scheme. The EUR 0.9 million grant supports Scil Technology’s research program to explore the therapeutic potential of repellent proteins for the treatment of rheumatoid arthritis (RA).

23 Jun 2011

Innovative Nail after Lengthening method can extend short thighbone by 26 centimeters

The MedUni Vienna's University Department of Trauma Surgery at Vienna General Hospital is a leader in the field of treatment of traumatic bone defects caused by accidents. A severely shortened thighbone as the result of an accident has now been able to be extended by using the innovative NAL method, creating an increase of 26 centimetres in only eight months.

22 Jun 2011

Frankincense may help treat painful arthritis

The answer to treating painful arthritis could lie in an age old herbal remedy - frankincense, according to Cardiff University scientists.

22 Jun 2011

Jamieson introduces UC-II undenatured collagen to relieve osteoarthritis pain

Most people think that arthritis is an inevitable part of aging. Today, Jamieson Laboratories has introduced UC-II undenatured collagen, a formulation that will turn back the clock on joint pain by naturally promoting the restoration of cartilage and inhibiting its deterioration. This new anti-aging formula taken only once daily is proven to be twice as effective as other joint remedies.

15 Jun 2011

DePuy ceramic-on-metal hip replacement gets FDA nod

The Food and Drug Administration has approved the first ceramic-on-metal total artificial hip system for osteoarthritis patients, a device made by Johnson & Johnson's DePuy Orthopaedics unit, the agency said Tuesday. The Pinnacle Complete Acetabular Hip System, combining a ceramic ball and a metal socket, has been sanctioned for people with osteoarthritis, the agency said in a news release.

15 Jun 2011

DePuy Orthopaedics receives FDA approval for ceramic-on-metal total artificial hip system

The U.S. Food and Drug Administration approved on June 13 the first ceramic-on-metal total artificial hip system for patients with osteoarthritis.

15 Jun 2011

Sarcoma UK releases inspiring film about people's experiences of living with bone cancer

Sarcoma UK releases an inspiring film about the experiences of people living with a rare form of cancer of soft tissue and bone, as part of Sarcoma Awareness Week.

13 Jun 2011

Scientists to develop new tissue engineering technology for patients with osteoarthritis

Medical scientists now have "clear" evidence that the damaged cartilage tissue in osteoarthritis and other painful joint disorders can be encouraged to regrow and regenerate, and are developing tissue engineering technology that could help millions of patients with those disorders.

10 Jun 2011

Patient enrollment complete in BioMimetic's Augment Rotator Cuff pilot trial

BioMimetic Therapeutics, Inc., a biotechnology company specializing in the development and commercialization of innovative bioactive products to promote the healing of musculoskeletal injuries and diseases, reported today that, ahead of previously announced guidance, the Company completed enrollment of 30 patients in a pilot clinical trial to assess the safety and clinical utility of AugmentTM Rotator Cuff Graft for the repair of large rotator cuff tears.

8 Jun 2011

Azellon receives MHRA approval to initiate stem cell bandage clinical trial in torn meniscal cartilage

Millions of people with knee injuries could benefit from a new type of stem cell bandage treatment if clinical trials are successful. The world's first clinical trial for the treatment of patients with torn meniscal cartilage has received approval from the UK regulatory agency, the MHRA1, to commence.

6 Jun 2011

Cartilage News and Research

Further Reading

Positive data from Histogenics' NeoCart Phase 2 study on knee cartilage injury

Janssen receives FDA Complete Response letter for SIMPONI sBLA to treat RA

Normal stem cell encourages growth of cancer stem cells and fuels ovarian cancer

Positive results from sarilumab Phase 2b trial on RA, ankylosing spondylitis

Research validates SpinalCyte's core technology to regrow the spinal disc

Arthroscopy as effective as open surgery for patients with common hip problem

Patients with motion limitations after knee surgery more likely to develop osteoarthritis

Arthroscopy restores range of motion in patients with common hip problem

Gender may increase risk of cartilage lesions in ACL knee injury

Serum-free media with growth factors can improve MSCs' cell fate regulation

Scil Technology receives public research grant for novel rheumatoid arthritis treatments

Innovative Nail after Lengthening method can extend short thighbone by 26 centimeters

Frankincense may help treat painful arthritis

Jamieson introduces UC-II undenatured collagen to relieve osteoarthritis pain

DePuy ceramic-on-metal hip replacement gets FDA nod

DePuy Orthopaedics receives FDA approval for ceramic-on-metal total artificial hip system

Sarcoma UK releases inspiring film about people's experiences of living with bone cancer

Scientists to develop new tissue engineering technology for patients with osteoarthritis

Patient enrollment complete in BioMimetic's Augment Rotator Cuff pilot trial

Azellon receives MHRA approval to initiate stem cell bandage clinical trial in torn meniscal cartilage

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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