Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Hip strengthening exercises reduce patellofemoral pain, improve female runners' gaits

Hip strengthening exercises performed by female runners not only significantly reduced patellofemoral pain -- a common knee pain experienced by runners -- but they also improved the runners' gaits, according to Indiana University motion analysis expert Tracy Dierks.

3 Jun 2011

Researchers receive CTSI Award for Translational Research in Maternal, Child, and Adolescent Health.

Patricia Dickson, MD, and Jennifer Yee, MD, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) researchers, will be honored on Thursday as recipients of the first UCLA Clinical and Translational Science Institute's (CTSI) Award for Translational Research in Maternal, Child, and Adolescent Health.

1 Jun 2011

Mount Sinai researchers identify protein signaling hyperactivity in human sarcoma cells

Researchers from Mount Sinai School of Medicine have discovered a protein signaling pathway that becomes hyperactivated in human sarcoma cells, suggesting that medications to inhibit this pathway may be effective in the treatment of human sarcomas. The research is published in the current issue of the journal Cancer Cell.

24 May 2011

Osteoarthritis directly linked to low-fat, high-carb food

Osteoarthritis is a degenerative joint disease and the most common cause of disability today. It was once considered a problem of the old but it is now commonly diagnosed in those as young as the mid-twenties and early thirties. According to the Arthritis Foundation, about four million, quality-adjusted life years are lost due to knee osteoarthritis alone.

20 May 2011

TissueGene commences enrollment in TG-C Phase II trial for severe knee osteoarthritis

TissueGene, Inc. announced today that it has initiated patient enrollment for a U.S. Phase II clinical trial of its lead product candidate TG-C. TG-C involves human allogeneic chondrocytes developed to produce the therapeutic protein TGF-beta1 for the regeneration of cartilage in patients suffering from severe osteoarthritis of the knee.

19 May 2011

Excaliber subsidiary merges with VistaGen

Excaliber Enterprises, Ltd. announced today that its wholly-owned subsidiary has merged with VistaGen Therapeutics, Inc., a private biotechnology company focused on stem cell-based drug rescue and drug development. As a result of the Merger, VistaGen is a wholly-owned subsidiary of Excaliber.

17 May 2011

Histogenics announces acquisition of ProChon Biotech

Histogenics Corporation, a privately held regenerative medicine company, announced today that it has acquired ProChon Biotech, Ltd. in a stock-for-stock exchange.

17 May 2011

Kensey Nash revenues decrease 7% to $18.6 million for third quarter fiscal 2011

Kensey Nash Corporation, a medical device company primarily focused on regenerative medicine for a wide range of medical procedures, today reported the results for its third quarter ended March 31, 2011.

6 May 2011

MDCT arthrography better than MR arthrography for diagnosing glenoid rim osseous lesions

MDCT arthrography is better than MR arthrography for diagnosing glenoid rim osseous lesions, lesions that have been identified as potential causes of recurrence after shoulder surgery, according to a new study.

4 May 2011

Fat stem cells may help develop new regenerative therapies for cardiovascular disease

Stem cells extracted from body fat may pave the way for the development of new regenerative therapies including soft tissue reconstruction following tumor removal or breast mastectomy surgery, the development of tissue-engineered cartilage or bone, and the treatment of cardiovascular disease.

4 May 2011

Sports-specialization can increase risk of injuries in young athletes

Competitive young athletes are under increasing pressure to play only one sport year round, but such specialization could increase the risk of injuries, a Loyola University Health System study has found.

3 May 2011

Early meniscus interventions may help prevent future osteoarthritis

Aging often means bad knees, and bad knees often mean osteoarthritis, a common and painful disability that affects more than 20 million Americans.

25 Apr 2011

Penile extenders represent an effective lengthening method for men

Surgeons should encourage men who request penile lengthening surgery to try non-invasive methods first and, in some cases, consider therapy to help them feel more positive about their body.

18 Apr 2011

Scientists create hollow nanofiber spheres for tissue repair

For the first time, scientists have made star-shaped, biodegradable polymers that can self-assemble into hollow, nanofiber spheres, and when the spheres are injected with cells into wounds, these spheres biodegrade, but the cells live on to form new tissue.

18 Apr 2011

CFN scientists develop 2-component polymer scaffolds for controlled 3-D cell culture

At Karlsruhe Institute of Technology (KIT), researchers of the DFG Center for Functional Nanostructures (CFN) succeeded in specifically cultivating cells on three-dimensional structures. The fascinating thing is that the cells are offered small "holds" in the micrometer range on the scaffold, to which they can adhere. Adhesion is possible to these holds only, not to the remaining structure.

7 Apr 2011

La Jolla acquires GliaMed's novel class of compounds

La Jolla Pharmaceutical Company today announced that it has acquired the rights to a novel class of compounds known as Regenerative Immunophilin Ligands from privately held GliaMed, Inc.

5 Apr 2011

New research reveals potential treatment for HO in children, soldiers

Promising new research reveals a potentially highly effective treatment for heterotopic ossification, a painful and often debilitating abnormal buildup of bone tissue. HO comes in two main forms—one that appears in children and is congenital, another that strikes wounded military personnel and surgery patients and is triggered by severe injuries and wounds.

4 Apr 2011

Open rhinoplasty effective for patients who undergo nose surgery

While rhinoplasty surgery is one of the most common surgery performed worldwide, many associate a stigma with it due to the unflattering nose surgeries of high profile celebrities.

2 Apr 2011

3D experiments reveal MSCs have potential to produce different cell types

A type of adult stem cell is now proving itself more versatile for research and therapies thanks to revolutionary 3D experiments. These cells have already shown great promise for repairing damaged bone and cartilage but until now have been fairly limited in the types of cells they can form in the laboratory.

31 Mar 2011

People with arthritis can benefit from exercise

An estimated 50 million adults in the United States suffer from arthritis. According to the Centers for Disease Control, one of the best ways to combat the onset of arthritis as well as to control pain and improve function is through exercise.

29 Mar 2011