Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Study identifies sailing injuries

Just as the site for the 2013 America's Cup has been announced, a study from Rhode Island Hospital highlights that the sport isn't always smooth sailing. The study was published recently in the journal Wilderness and Environmental Medicine.

5 Jan 2011

CDK1 protein deactivates EZH2 enzyme that causes cancer spread

By sticking a chemical group to it at a specific site, a protein arrests an enzyme that may worsen and spread cancer, an international research team led by scientists at The University of Texas MD Anderson Cancer Center reports in the January issue of Nature Cell Biology.

4 Jan 2011

Innovative approach in revision plastic surgery

Corrective cosmetic surgery cases are definitely on the rise. In fact, revision plastic surgery comprises nearly half of the patients Dr. Sam Rizk, Manhattan Facial Plastic Surgeon treats in his Park Avenue practice. From windblown tight facelifts to ski slope shaped, pointy noses, Dr. Rizk has fixed them all. He believes in a natural looking approach when it comes to doing any facial plastic surgery. Dr. Rizk knows that every nose is as unique as every patient's face is different.

3 Jan 2011

Omega-3 fatty acids may reduce inflammation, disease symptoms and cartilage degeneration

Omega-3 fatty acids from seafood may reduce inflammation, symptoms of gum disease and risk of abnormal heartbeats early after cardiac surgery. One type of omega-3, DHA (docosahexaenoic acid), may also have lasting benefits in visual function for years in children whose mothers consume sufficient prenatal DHA.

30 Dec 2010

FDA stops pain drug trial over safety concerns

Johnson & Johnson revealed Tuesday this week that a clinical trial of its experimental pain drug, fulranumab, has been stopped after the Food and Drug Administration expressed concerns that patients taking the drug could suffer increased joint damage.

29 Dec 2010

New derivation of stem cells from fat cells hold promise for therapeutic, cosmetic benefits

Two studies appearing in the current issue of Cell Transplantation 19(10) discuss stem cells derived from adipose (fat) cells and their potential use in plastic surgery and tissue reconstruction. The studies are now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/ .

24 Dec 2010

4SC AG's Phase IIb study evaluates efficacy of vidofludimus in RA patients

4SC AG, a drug discovery and development company focused on autoimmune and cancer indications, today reported that it has completed enrolment of its COMPONENT Phase IIb study with vidofludimus, an oral inhibitor of IL-17 release, in rheumatoid arthritis (RA) patients. Data from the trial are expected to be announced in Q2 2011.

20 Dec 2010

Arthrosurface conducts first knee procedure based on HemiCAP platform technology

Arthrosurface, Inc., the developer of less-invasive joint resurfacing systems, announced that it has performed its first biological knee procedure based on the company's proven HemiCAP® platform technology.

19 Dec 2010

BioMimetic granted Canadian notice of patent allowance covering rhPDGF-BB platform technology formulations

BioMimetic Therapeutics, Inc. announced today the Canadian Intellectual Property Office (CIPO) has allowed patent application No. 2,583,823 titled "Platelet Derived Growth Factor (PDGF) Compositions and Methods of Use Thereof". The new patent will remain in force until October 2025, during which time it will prohibit the marketing of similar or generic versions of the Company's Augment™ orthopedic product line and certain other rhPDGF-BB product formulations.

17 Dec 2010

Pediatric plastic surgeon reconstructs patient's jaw

Pediatric plastic surgeon Rohit Khosla, MD, had never seen a case like it: the 12-year-old boy's face ballooned with a rare, aggressive bone tumor. Although it was non-cancerous, the tumor was destroying the patient's jaw. Khosla knew he would need an innovative approach to save the boy's ability to chew.

17 Dec 2010

Researchers discover allium vegetable consumption may lower hip osteoarthritis

Researchers at King's College London and the University of East Anglia have discovered that women who consume a diet high in allium vegetables, such as garlic, onions and leeks, have lower levels of hip osteoarthritis

16 Dec 2010

Anoles key to medically applicable regeneration?

Anolis lizards first entered Arizona State University biologist Kenro Kusumi's life in 1980 when, as a member of a junior curator program, he recorded in his field notebook that he had found an Anolis egg on a field trip. Kusumi still has those notes, along with other memorabilia that document the influence that both his early life and more recent experiences have had on his current pursuits in developmental biology.

15 Dec 2010

CGEN-15001 administration shows dramatic therapeutic potential in CIA animal model

Compugen Ltd. announced today that administration of CGEN-15001 in an animal model of rheumatoid arthritis dramatically ameliorates the clinical symptoms of the disease.

15 Dec 2010

New research reports more than 10% of RA patients lack health literacy

Many patients seen at a rheumatology clinic—including some with a long history of rheumatoid arthritis (RA)—don't recognize important terms related to their health and medical treatment, reports a study in the December issue of JCR: Journal of Clinical Rheumatology.

15 Dec 2010

Ascension Orthopedics reports first implantation of PyroTITAN Humeral Resurfacing Implant in France

Ascension Orthopedics, Inc., a market leader in PyroCarbon orthopedic implants, announces the first implantation of the PyroTITAN™ Humeral Resurfacing Implant in France. The PyroTITAN was implanted in a 68-year-old patient suffering from painful primary arthritis with synovial osteochondromotosis at Imperial Park Clinic in Nice – making it a surgical first in continental Europe. The patient was discharged from the hospital the next day and reported good pain relief 10 days after surgery.

13 Dec 2010

New York City surgeon performs first revision rhinoplasty cases with FDA approved PDS Plate

Today Dr. Steven Pearlman, prominent facial plastic and reconstructive surgeon based in New York City, will be performing one of the first revision rhinoplasty cases with the newly FDA approved PDS Plate. This revolutionary procedure will mark a giant leap in the world of cosmetic and reconstructive surgery.

13 Dec 2010

Nuss Procedure safe and effective for chest deformity

Since 1987, when a surgeon at Children's Hospital of The King's Daughters developed a minimally-invasive surgery to correct sunken chest, the procedure has been adopted world-wide as a standard of care and continually refined to increase its effectiveness and safety, according to a paper published in the December issue of the Annals of Surgery.

10 Dec 2010

Audax Medical licenses novel TBL technology to fix broken bones from Brown

Here's the vision: an elderly woman comes into the emergency room after a fall. She has broken her hip. The orthopaedic surgeon doesn't come with metal plates or screws or shiny titanium ball joints. Instead, she pulls out a syringe filled with a new kind of liquid that will solidify in seconds and injects into the break. Over time, new bone tissue will take its place, encouraged by natural growth factors embedded in the synthetic molecules of the material.

8 Dec 2010

Cephalon, Mesoblast to develop, commercialize novel adult MPC therapeutics

Cephalon, Inc. and Mesoblast Limited, today announced they have entered into a strategic alliance to develop and commercialize novel adult Mesenchymal Precursor Stem Cell therapeutics for degenerative conditions of the cardiovascular and central nervous systems.

8 Dec 2010

BioMimetic Therapeutics to assess safety, clinical utility of Augment Rotator Cuff Graft

BioMimetic Therapeutics, Inc. today announced it initiated enrollment in a pilot clinical trial to assess the safety and clinical utility of AugmentTM Rotator Cuff Graft for the repair of large rotator cuff tears. The randomized, controlled pilot trial is expected to include enrollment of up to 30 patients.

8 Dec 2010

Cartilage News and Research

Further Reading

Study identifies sailing injuries

CDK1 protein deactivates EZH2 enzyme that causes cancer spread

Innovative approach in revision plastic surgery

Omega-3 fatty acids may reduce inflammation, disease symptoms and cartilage degeneration

FDA stops pain drug trial over safety concerns

New derivation of stem cells from fat cells hold promise for therapeutic, cosmetic benefits

4SC AG's Phase IIb study evaluates efficacy of vidofludimus in RA patients

Arthrosurface conducts first knee procedure based on HemiCAP platform technology

BioMimetic granted Canadian notice of patent allowance covering rhPDGF-BB platform technology formulations

Pediatric plastic surgeon reconstructs patient's jaw

Researchers discover allium vegetable consumption may lower hip osteoarthritis

Anoles key to medically applicable regeneration?

CGEN-15001 administration shows dramatic therapeutic potential in CIA animal model

New research reports more than 10% of RA patients lack health literacy

Ascension Orthopedics reports first implantation of PyroTITAN Humeral Resurfacing Implant in France

New York City surgeon performs first revision rhinoplasty cases with FDA approved PDS Plate

Nuss Procedure safe and effective for chest deformity

Audax Medical licenses novel TBL technology to fix broken bones from Brown

Cephalon, Mesoblast to develop, commercialize novel adult MPC therapeutics

BioMimetic Therapeutics to assess safety, clinical utility of Augment Rotator Cuff Graft

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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