Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Gene may play a broader role in embryonic organ development

An international study led by the medical Faculty of the University of Bonn has identified a gene that plays an important role in the development of the human embryo. If it is altered, malformations of various organ systems can result.

15 Nov 2022

Study finds a possible new target to fight osteoarthritis

Wear and tear on joints can lead to inflammation, breakdown of cartilage and development of osteoarthritis.

14 Oct 2022

Researchers identify a new gene implicated in rare lysosomal storage disorder

In a rare disease called mucolipidosis type II, people’s hearts and abdomens swell, and their bones grow malformed.

6 Oct 2022

Researchers find new way to deliver a protein quickly, effectively and briefly to the brain

Many diseases have at their origin a protein that does not function properly. Now, a multidisciplinary research team with Texas A&M AgriLife and Texas A&M University has found a way to deliver a protein quickly, effectively and briefly to the brain, with therapeutic and scientific implications.

28 Sep 2022

New modeling technique can help better understand the development of rheumatoid arthritis

A new modeling technique can better predict how bones, cartilage, and cellular tissues will be affected by rheumatoid arthritis in small joints.

28 Sep 2022

Research pits the simulation of beta radiation in cancer treatment against analytical method

A new paper published in EPJ Plus and authored by Eduardo De Paiva, from the Division of Medical Physics at the Institute of Radiation Protection and Dosimetry, Rio de Janeiro, Brazil, pits the gold standard simulation method used to calculate the interaction of the ionizing radiation with matter and estimate the radiation dose delivered to a target organ—Monte Carlo (MC) simulation — against an alternative analytic method, the Loevinger formula.

20 Sep 2022

OU researcher may have found a way to reduce the number of TBI surgeries to just one

A battered woman. A wounded warrior. A football player. All from completely different worlds. Yet, all are connected by one thing – traumatic brain injury.

20 Sep 2022

Two novel tools may simplify, quicken and improve ear reconstruction surgery

According to the National Birth Defects Prevention Network, one in every 8,000 to 10,000 births in the United States result in one of two congenital malformations of the ear: microtia (the child is born with only a cartilage stump for an ear) or anotia (the complete lack of an ear).

15 Sep 2022

Treg transplantation improves bone remodeling, study says

The building blocks of a structure consist of load-bearing elements that rarely change despite renovations or repairs. They remain intact and consistent over time, but in the human body, our building blocks do just the opposite.

13 Sep 2022

Researchers identify protein that plays a critical role in rheumatoid arthritis damage

Scientists have identified a protein known as sulfatase-2 that plays a critical role in the damage caused by rheumatoid arthritis.

8 Sep 2022

Study establishes link between Piezo1 and intracellular cholesterol levels during neural development

A new University of California, Irvine-led study reveals how mechanical forces and tissue mechanics influence the morphology of the developing brain, and establishes a direct link in neural stem cells between Piezo1, a mechanically-activated ion channel, and intracellular cholesterol levels during neural development.

8 Sep 2022

Parathyroid hormone administered to tendons promotes meniscus regeneration in rat model

The knee meniscus is an important tissue that protects the joint; if the meniscus is damaged-;by sports injury or aging–it often does not heal on its own.

26 Aug 2022

Mouse embryoids offer a promising model system to spur research into embryonic development and disease

Scientists funded in part by the National Institutes of Health have generated a mouse embryo model, or embryoid, that develops beyond neurulation—formation of the neural tube, which gives rise to the central nervous system—and closely mirrors natural mouse embryos 8.5 days after fertilization.

25 Aug 2022

Super-resolution imaging reveals how disease causes cells to reorder their DNA incorrectly

Imagine you're trying to do a job and all of the information you need to do it is in a few books at the library.

22 Aug 2022

New gel-based cartilage substitute is stronger and more durable than the real thing

Over-the-counter pain relievers, physical therapy, steroid injections -- some people have tried it all and are still dealing with knee pain.

11 Aug 2022

NHS Golden Jubilee orthopedic surgeons perform the first meniscal transplant in Scotland

Orthopedic surgeons at NHS Golden Jubilee have performed the first meniscal transplant on a patient in Scotland.

5 Aug 2022

Eating fish and seafood reduces risk of rheumatoid arthritis

Scientists determine the relationship between meat consumption and rheumatoid arthritis.

4 Aug 2022

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

Wake Forest Institute for Regenerative Medicine researchers are using a tumor organoid system to examine the effects of metabolites secreted by bacteria on a specialized immunotherapy – immune checkpoint blockage, a promising cancer treatment development – to determine why some patients don't respond or develop a resistance to the treatment over time.

29 Jul 2022

Cornell researchers engineer a biohybrid composite material that mimics natural tissue

Producing biomaterials that match the performance of cartilage and tendons has been an elusive goal for scientists, but a new material created at Cornell demonstrates a promising new approach to mimicking natural tissue.

11 Jul 2022

Study focuses on how telomerase activity affects the regenerative potential of stem cells in human urine

The Wake Forest Institute for Regenerative Medicine researchers who were the first to identify that stem cells in human urine have potential for tissue regenerative effects, continue their investigation into the power of these cells.

28 Jun 2022