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Researchers identify mechanisms necessary to live without insulin

Several millions of people around the world suffer from insulin deficiencies. Insulin is a hormone, secreted by the beta cells in the pancreas, which plays a major role in the regulation of energy substrates such as glucose.

4 Sep 2013

Study shows how stomach bacteria manipulates human immune system to survive in stomach

Helicobacter pylori is a bacterium that establishes a life-long stomach infection in humans, which in some cases can lead to duodenal ulcers or stomach cancer. New research, presented at this week's Society for General Microbiology Autumn Conference, gives us a clearer understanding of how these bacteria can manipulate the human immune system to survive in the mucosal lining of the stomach.

4 Sep 2013

New recombinant antibody can recognize MSCs in umbilical cord blood

A new recombinant antibody can detect and isolate mesenchymal stem cells (MSCs), a nonembryonic source of stem cells with promising applications in tissue engineering, blood stem cell transplantation, and treatments for immune-mediated disorders.

4 Sep 2013

Scientists provide proof of principle for drug-based treatment of acute pancreatitis

Scientists have for the first time provided proof of principle for a drug-based treatment of acute pancreatitis - a disease which is often alcohol-related and for which currently there is no treatment.

4 Sep 2013

UCLA researchers receives $13M Early Translational grants to advance innovative discoveries using stem cells

Four researchers from UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have received Early Translational Research Awards totaling approximately $13 million from the California Institute for Regenerative Medicine, the state's stem cell agency. The UCLA researchers received four of the 12 total awards; no other institution received more than one.

4 Sep 2013

BIDMC receives grant to study new noninvasive neurophysiologic intervention for spinal cord injuries

Beth Israel Deaconess Medical Center has been awarded a grant from the National Institutes of Health to investigate the use of a new noninvasive neurophysiologic intervention for the treatment of patients with spinal cord injuries.

4 Sep 2013

Blind mole-rats live underground in low-oxygen environments, are long-lived and resistant to cancer

Like naked mole-rats (Heterocephalus gaber), blind mole-rats (of the genus Spalax) live underground in low-oxygen environments, are long-lived and resistant to cancer. A new study demonstrates just how cancer-resistant Spalax are, and suggests that the adaptations that help these rodents survive in low-oxygen environments also play a role in their longevity and cancer resistance.

4 Sep 2013

Study: Changes in expression of various isoforms might play role in cancer development

Spool-like proteins called histones play a crucial role in packaging the nearly seven feet of DNA found in most human cells. A new study shows that a group of histones that are thought to behave the same way actually are functionally distinct proteins.

4 Sep 2013

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Chronic granulomatous disease, or CGD, is a diverse group of inherited diseases in which certain cells of the immune system have difficulty forming reactive oxygen compounds, most importantly superoxide radicals. These are used by these white blood cells to kill certain bacteria.

3 Sep 2013

Viralytics releases financial results for 2013

Viralytics Limited (ASX:VLA, OTCQX:VRACY) has released its financial results for the year ended 30 June 2013.

3 Sep 2013

Sigma Life Science signs license agreement with Horizon Discovery for CompoZr ZFN technology

Sigma-Aldrich Corporation today announced that Sigma Life Science, its innovative biological products and services business, has entered a non-exclusive license agreement with Horizon Discovery for use of Sigma's CompoZr Zinc Finger Nuclease technology.

3 Sep 2013

Research shows how mucosal surfaces in body respond to C. albicans to prevent damage

Candida albicans is a common fungus found living in, and on, many parts of the human body. Usually this species causes no harm to humans unless it can breach the body's immune defences, where can lead to serious illness or death.

3 Sep 2013

New joint program could improve patient care, physician and staff morale

The common refrain about health care is that it's a broken system. A new joint program between the University of California, Los Angeles and the University of Southern California, demonstrates a way to mend the system with a new patient-centered program that is getting raves from patients, as well as the residents and nurses who provide their care. Results from the program are highlighted in a study being released in September.

3 Sep 2013

Transport protein actively extrudes chemicals from embryo of zebrafish

Fish possess a number of different mechanisms for protection against harmful substances in an aquatic environment. These include, for example, molecular transport systems, such as the so called ABC (ATP binding cassette) transporters, which prevent the penetration of toxic substances into cells. ABC transporters have been well investigated for mammals.

3 Sep 2013

Argininosuccinic aciduria (ASA) and gene therapy: an interview with Dr Julien Baruteau, UCL Institute for Women's Health, London

This rare genetic condition can theoretically affect patients at any age but symptoms are more often observed in childhood and even uncommonly during the first days of life.

2 Sep 2013

ddPCR technology can be used to reproducibly quantify microRNA in plasma

A study published online in Nature Methods today demonstrated that Droplet Digital PCR (ddPCR-) technology can be used to precisely and reproducibly quantify microRNA (miRNA) in plasma and serum across different days, paving the way for further development of miRNA and other nucleic acids as circulating biomarkers.

2 Sep 2013

Drug for children with sickle cell anemia reduces hospitalizations and treatment costs

A drug proven effective for treatment of adults and children with sickle cell anemia reduced hospitalizations and cut annual estimated medical costs by 21 percent for affected infants and toddlers, according to an analysis led by St. Jude Children's Research Hospital. The report appears today in the advance online edition of the journal Pediatrics.

2 Sep 2013

Cell News and Research

Researchers identify mechanisms necessary to live without insulin

Study shows how stomach bacteria manipulates human immune system to survive in stomach

New recombinant antibody can recognize MSCs in umbilical cord blood

Scientists provide proof of principle for drug-based treatment of acute pancreatitis

UCLA researchers receives $13M Early Translational grants to advance innovative discoveries using stem cells

BIDMC receives grant to study new noninvasive neurophysiologic intervention for spinal cord injuries

Blind mole-rats live underground in low-oxygen environments, are long-lived and resistant to cancer

Study: Changes in expression of various isoforms might play role in cancer development

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Viralytics releases financial results for 2013

Sigma Life Science signs license agreement with Horizon Discovery for CompoZr ZFN technology

Research shows how mucosal surfaces in body respond to C. albicans to prevent damage

New joint program could improve patient care, physician and staff morale

Transport protein actively extrudes chemicals from embryo of zebrafish

Argininosuccinic aciduria (ASA) and gene therapy: an interview with Dr Julien Baruteau, UCL Institute for Women's Health, London

ddPCR technology can be used to reproducibly quantify microRNA in plasma

Drug for children with sickle cell anemia reduces hospitalizations and treatment costs

Researchers pinpoint ways to counter effects of antibiotics-driven depletion of gut-dwelling bacteria

Holistic approach to understand and treat TB

Nanostructures made of DNA strands can encapsulate, release small-molecule drugs

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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