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Study identifies new tool to accurately analyze mtDNA deletions associated with diseases, aging

A study published today in Aging Cell identifies a new tool to accurately analyze extremely rare mitochondrial DNA deletions associated with a range of diseases and disorders as well as aging. This approach, which relies on Droplet Digital PCR (ddPCR-) technology, will help researchers explore mtDNA deletions as potential disease biomarkers.

4 Sep 2013

Research finding provides blueprint for understanding how the brain communicates with itself

During a normal conversation, your brain is constantly adjusting the volume to soften the sound of your own voice and boost the voices of others in the room.

4 Sep 2013

Blocking a protein helps virus to thrive and restore immune function to fight HCV infection

The hepatitis C virus hijacks the body's immune system, leaving T cells unable to function. A new study in animal models suggests that blocking a protein that helps the virus thrive could restore immune function, allowing the body to fight infection. The work, led by teams at The Research Institute at Nationwide Children's Hospital and Emory University, was published online Aug. 26 in the Proceedings of the National Academy of Sciences.

4 Sep 2013

New mechanism operates specific protein in brain to bring delay in aging

Among scientists, the role of proteins called sirtuins in enhancing longevity has been hotly debated, driven by contradictory results from many different scientists. But new research at Washington University School of Medicine in St. Louis may settle the dispute.

4 Sep 2013

Study looks for molecular changes in genome caused by multiple sclerosis

The National Institutes of Health (NIH) awarded Benaroya Research Institute at Virginia Mason (BRI) a $1.9 million grant to find marks in the human genome which can explain why some white blood cells cause damage to the spinal cord and brain in multiple sclerosis (MS).

4 Sep 2013

Research on long-lived proteins may lead to better understanding of molecular basis of aging

Proteins are the chief actors in cells, carrying out the duties specified by information encoded in our genes. Most proteins live only two days or less, ensuring that those damaged by inevitable chemical modifications are replaced with new functional copies.

4 Sep 2013

Over half of people with hypertension unaware of the condition, very few take adequate treatment

A global study has found that many patients don't know they have hypertension and, even if they do, too few are receiving adequate drug therapy for their hypertension.

4 Sep 2013

Researchers find way to resynchronize cardiac motion following heart attack

Mayo Clinic researchers have found a way to resynchronize cardiac motion following a heart attack using stem cells. Scientists implanted engineered stem cells, also known as induced pluripotent stem (iPS) cells, into damaged regions of mouse hearts following a heart attack.

4 Sep 2013

Precisely designed macromolecule mimics binding of HIV to immune system cells

A precisely designed macromolecule that mimics the binding of HIV to immune system cells could be used to stop the virus from physically entering the body, according to a new study led by a materials scientist at Queen Mary University of London.

4 Sep 2013

Researchers identify mechanisms necessary to live without insulin

Several millions of people around the world suffer from insulin deficiencies. Insulin is a hormone, secreted by the beta cells in the pancreas, which plays a major role in the regulation of energy substrates such as glucose.

4 Sep 2013

Study shows how stomach bacteria manipulates human immune system to survive in stomach

Helicobacter pylori is a bacterium that establishes a life-long stomach infection in humans, which in some cases can lead to duodenal ulcers or stomach cancer. New research, presented at this week's Society for General Microbiology Autumn Conference, gives us a clearer understanding of how these bacteria can manipulate the human immune system to survive in the mucosal lining of the stomach.

4 Sep 2013

New recombinant antibody can recognize MSCs in umbilical cord blood

A new recombinant antibody can detect and isolate mesenchymal stem cells (MSCs), a nonembryonic source of stem cells with promising applications in tissue engineering, blood stem cell transplantation, and treatments for immune-mediated disorders.

4 Sep 2013

Scientists provide proof of principle for drug-based treatment of acute pancreatitis

Scientists have for the first time provided proof of principle for a drug-based treatment of acute pancreatitis - a disease which is often alcohol-related and for which currently there is no treatment.

4 Sep 2013

UCLA researchers receives $13M Early Translational grants to advance innovative discoveries using stem cells

Four researchers from UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have received Early Translational Research Awards totaling approximately $13 million from the California Institute for Regenerative Medicine, the state's stem cell agency. The UCLA researchers received four of the 12 total awards; no other institution received more than one.

4 Sep 2013

BIDMC receives grant to study new noninvasive neurophysiologic intervention for spinal cord injuries

Beth Israel Deaconess Medical Center has been awarded a grant from the National Institutes of Health to investigate the use of a new noninvasive neurophysiologic intervention for the treatment of patients with spinal cord injuries.

4 Sep 2013

Blind mole-rats live underground in low-oxygen environments, are long-lived and resistant to cancer

Like naked mole-rats (Heterocephalus gaber), blind mole-rats (of the genus Spalax) live underground in low-oxygen environments, are long-lived and resistant to cancer. A new study demonstrates just how cancer-resistant Spalax are, and suggests that the adaptations that help these rodents survive in low-oxygen environments also play a role in their longevity and cancer resistance.

4 Sep 2013

Study: Changes in expression of various isoforms might play role in cancer development

Spool-like proteins called histones play a crucial role in packaging the nearly seven feet of DNA found in most human cells. A new study shows that a group of histones that are thought to behave the same way actually are functionally distinct proteins.

4 Sep 2013

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Chronic granulomatous disease, or CGD, is a diverse group of inherited diseases in which certain cells of the immune system have difficulty forming reactive oxygen compounds, most importantly superoxide radicals. These are used by these white blood cells to kill certain bacteria.

3 Sep 2013

Viralytics releases financial results for 2013

Viralytics Limited (ASX:VLA, OTCQX:VRACY) has released its financial results for the year ended 30 June 2013.

3 Sep 2013

Sigma Life Science signs license agreement with Horizon Discovery for CompoZr ZFN technology

Sigma-Aldrich Corporation today announced that Sigma Life Science, its innovative biological products and services business, has entered a non-exclusive license agreement with Horizon Discovery for use of Sigma's CompoZr Zinc Finger Nuclease technology.

3 Sep 2013

Cell News and Research

Study identifies new tool to accurately analyze mtDNA deletions associated with diseases, aging

Research finding provides blueprint for understanding how the brain communicates with itself

Blocking a protein helps virus to thrive and restore immune function to fight HCV infection

New mechanism operates specific protein in brain to bring delay in aging

Study looks for molecular changes in genome caused by multiple sclerosis

Research on long-lived proteins may lead to better understanding of molecular basis of aging

Over half of people with hypertension unaware of the condition, very few take adequate treatment

Researchers find way to resynchronize cardiac motion following heart attack

Precisely designed macromolecule mimics binding of HIV to immune system cells

Researchers identify mechanisms necessary to live without insulin

Study shows how stomach bacteria manipulates human immune system to survive in stomach

New recombinant antibody can recognize MSCs in umbilical cord blood

Scientists provide proof of principle for drug-based treatment of acute pancreatitis

UCLA researchers receives $13M Early Translational grants to advance innovative discoveries using stem cells

BIDMC receives grant to study new noninvasive neurophysiologic intervention for spinal cord injuries

Blind mole-rats live underground in low-oxygen environments, are long-lived and resistant to cancer

Study: Changes in expression of various isoforms might play role in cancer development

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Viralytics releases financial results for 2013

Sigma Life Science signs license agreement with Horizon Discovery for CompoZr ZFN technology

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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