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Study shows how brain integrates inputs from different senses in complex circuits of nerve cells

A new publication in the top-ranked journal Neuron sheds new light onto the unknown processes on how the brain integrates the inputs from the different senses in the complex circuits formed by molecularly distinct types of nerve cells. The work was led by new Ume- University associate professor Paolo Medini.

21 Aug 2013

UC Davis graduate discovers how eIF4E protein acts upon cancer-promoting mRNA molecules

Researchers have long known that high levels of a specific protein in human cells are linked to tumor growth - but no one has fully understood how.

21 Aug 2013

Research suggests gene therapy approach may be feasible option to treat Rett Syndrome

The concept behind gene therapy is simple: deliver a healthy gene to compensate for one that is mutated. New research published today in the Journal of Neuroscience suggests this approach may eventually be a feasible option to treat Rett Syndrome, the most disabling of the autism spectrum disorders.

21 Aug 2013

Studies reveal potential of HB-EGF in protecting intestines from diverse types of injury

It's not often that one treatment offers therapeutic potential for multiple conditions. However, after more than two decades of research, Gail Besner, MD, principal investigator for the Center for Perinatal Research and pediatric surgeon for the Department of Pediatric Surgery at Nationwide Children's Hospital, and her team have found that this may just be the case with HB-EGF, or heparin-binding EGF-like growth factor.

21 Aug 2013

Combination of anti-nausea drug and turmeric spice target cancer cells

In a laboratory, preclinical study recently published by the journal Organic & Biomolecular Chemistry, Virginia Commonwealth University Massey Cancer Center researchers combined structural features from anti-nausea drug thalidomide with common kitchen spice turmeric to create hybrid molecules that effectively kill multiple myeloma cells.

20 Aug 2013

Increased flexibility in live cell imaging offered by Olympus’ new advanced optical modules in its inverted microscope frame design

Extending the capabilities of the fully customisable IX3 inverted microscope frame, Olympus has expanded its range of compatible, interchangeable optical modules. Ease-of-use and accuracy are vastly improved via new motorised components, which also present a cost-efficient means to gradually upgrade to a fully motorised microscope system.

From Evident Corporation - Life Sciences 20 Aug 2013

D-Pharm announces promising results with drug candidates in models of HAT and malaria

D-Pharm Ltd., announced today on-line publication of promising results with its drug candidates, DP-460 and DP-b99, in models of human African trypanosomiasis (HAT) and malaria.

20 Aug 2013

Even in advanced stages total tumor size can have major impact on survival in lung cancer patients

For the two-thirds of lung cancer patients with locally advanced or metastatic disease, tumor size is not used currently to predict overall survival times. A new study, however, led by UT Southwestern Medical Center researchers has shown that even in advanced stages total tumor size can have a major impact on survival.

20 Aug 2013

Researchers identify key transcription factor linked with treatment-resistant prostate cancer

Prostate cancer is one of the most common forms of cancer in men and the leading cause of cancer deaths in white, African-American and Hispanic men, according to the Centers for Disease Control. Current treatment of prostate cancer targets androgens, hormones which promote the growth and spread of cancer cells.

20 Aug 2013

Chinese herbal medicine JSK protects against injury caused by damage to spinal cord blood vessels

A new study published in Restorative Neurology and Neuroscience demonstrates that Chinese herbal medicine Ji-Sui-Kang (JSK), given systemically for three weeks after injury in rats, improved locomotor function, reduced tissue damage, and preserved the structure of neural cells compared to control rats.

20 Aug 2013

Researchers find new strategy that has potential to change standard of care for DLBCL patients

Patients with an aggressive lymphoma that often relapses and kills within two years experienced a remission of their cancer and stayed disease-free as long as 28 months after taking a commercially-available drug that made chemotherapy more effective.

20 Aug 2013

Research may shed light on what causes people to suffer from life-threatening anxiety disorders

New research at Rutgers University may help shed light on how and why nervous system changes occur and what causes some people to suffer from life-threatening anxiety disorders while others are better able to cope.

20 Aug 2013

Advance team of molecules produced by primary tumor is responsible for lung cancer metastasis

Cancer metastasis requires tumor cells to acquire properties that allow them to escape from the primary tumor site, travel to a distant place in the body, and form secondary tumors. But first, an advance team of molecules produced by the primary tumor sets off a series of events that create a network of nurturing blood vessels for arriving primary tumor cells to set up shop.

20 Aug 2013

Clinical trial shows type-1 diabetes patients treated with teplizumab exhibit greater response to therapy

Primary results from a new clinical trial show that patients with type 1 diabetes treated with the monoclonal antibody teplizumab (MacroGenics, Inc.) exhibit greater preservation of C-peptide, a biomarker of islet cell function, compared to controls.

20 Aug 2013

Study shows complement activation plays an important role in inherited macular degeneration

In a study published on line this week in the journal Human Molecular Genetics, Drs. Donita Garland, Rosario Fernandez-Godino, and Eric Pierce of the Ocular Genomics Institute at the Massachusetts Eye and Ear, Harvard Medical School, along with their colleagues, reported the unexpected finding that in mice genetically engineered to have an inherited form of macular degeneration, turning off the animals' complement system, a part of the immune system, prevented the disease.

20 Aug 2013

Researchers create mouse models to advance the study of unusual deadly diseases

By directly manipulating a portion of the prion protein-coding gene, Whitehead Institute researchers have created mouse models of two neurodegenerative diseases that are fatal in humans. The highly accurate reproduction of disease pathology seen with these models should advance the study of these unusual but deadly diseases.

20 Aug 2013

Report demonstrates clinical use of novel biomarker to assess cancer progression, inflammation

A groundbreaking peer reviewed case report by Dr. Isaac Eliaz, M.D. of Amitabha Medical Clinic, demonstrates for the first time the clinical use of novel biomarker galectin-3 to assess cancer progression and inflammation.

19 Aug 2013

IBN researchers one step closer to viable tissue replacements

Researchers at the Institute of Bioengineering and Nanotechnology have developed a simple method of organizing cells and their microenvironments in hydrogel fibers. Their unique technology provides a feasible template for assembling complex structures, such as liver and fat tissues, as described in their recent publication in Nature Communications.

19 Aug 2013

New type of cancer immunotherapy harnesses body's immune system to attack tumors

By carefully adjusting the function of crucial immune cells, scientists may have developed a completely new type of cancer immunotherapy—harnessing the body's immune system to attack tumors. To accomplish this, they had to thread a needle in immune function, shrinking tumors without triggering unwanted autoimmune responses.

19 Aug 2013

Powerful mechanism helps viruses evade body's immune response

Researchers at the Salk Institute for Biological Studies have discovered a powerful mechanism by which viruses such as influenza, West Nile and Dengue evade the body's immune response and infect humans with these potentially deadly diseases. The findings may provide scientists with an attractive target for novel antiviral therapies.

19 Aug 2013

Cell News and Research

Study shows how brain integrates inputs from different senses in complex circuits of nerve cells

UC Davis graduate discovers how eIF4E protein acts upon cancer-promoting mRNA molecules

Research suggests gene therapy approach may be feasible option to treat Rett Syndrome

Studies reveal potential of HB-EGF in protecting intestines from diverse types of injury

Combination of anti-nausea drug and turmeric spice target cancer cells

Increased flexibility in live cell imaging offered by Olympus’ new advanced optical modules in its inverted microscope frame design

D-Pharm announces promising results with drug candidates in models of HAT and malaria

Even in advanced stages total tumor size can have major impact on survival in lung cancer patients

Researchers identify key transcription factor linked with treatment-resistant prostate cancer

Chinese herbal medicine JSK protects against injury caused by damage to spinal cord blood vessels

Researchers find new strategy that has potential to change standard of care for DLBCL patients

Research may shed light on what causes people to suffer from life-threatening anxiety disorders

Advance team of molecules produced by primary tumor is responsible for lung cancer metastasis

Clinical trial shows type-1 diabetes patients treated with teplizumab exhibit greater response to therapy

Study shows complement activation plays an important role in inherited macular degeneration

Researchers create mouse models to advance the study of unusual deadly diseases

Report demonstrates clinical use of novel biomarker to assess cancer progression, inflammation

IBN researchers one step closer to viable tissue replacements

New type of cancer immunotherapy harnesses body's immune system to attack tumors

Powerful mechanism helps viruses evade body's immune response

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