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High mobility group (HMG) genes and cancer: an interview with Dr. Linda Resar, Johns Hopkins University School of Medicine

High mobility group A genes are highly expressed in all aggressive cancers studied to date. These genes encode the high mobility group A (HMGA) proteins. In other words, these genes provide the genetic “code” necessary to produce HMGA proteins.

8 Aug 2013

Findings could lead to development of therapeutic agents for age-related diseases

Scientists at Sanford-Burnham Medical Research Institute have identified a key factor that regulates the autophagy process, a kind of cleansing mechanism for cells in which waste material and cellular debris is gobbled up to protect cells from damage, and in turn, modulates aging.

8 Aug 2013

Penn State researchers find that protein changes can control gene functions

A Penn State-led research team has found that changes to proteins called histones, which are associated with DNA, can control whether or not a gene is allowed to function. The changes may be important in maintaining the genes' "expression potential" so that future cells behave as their parent cells did.

8 Aug 2013

Study finds no evidence that retired NFL players suffer chronic traumatic encephalopathy

The media have widely reported that retired NFL players are at risk for a neurodegenerative disorder called chronic traumatic encephalopathy, which causes symptoms such as aggression, depression, suicidality and progressive dementia.

8 Aug 2013

Researchers unveil comprehensive portrait of the genome of world's first immortal cell line

A team from the University of Washington has unveiled a comprehensive portrait of the genome of the world's first immortal cell line, known as HeLa. The cell line was derived in 1951 from an aggressive cervical cancer that killed Henrietta Lacks, a 31-year-old African-American tobacco farmer and mother of five - the subject of the 2010 New York Times bestseller, The Immortal Life of Henrietta Lacks.

8 Aug 2013

Ret enzyme may be a novel therapeutic target in selected groups of breast cancer patients

Scientists at the MedUni Vienna, in collaboration with a working group led by Nancy Hynes at the University of Basel, have discovered a new approach in the treatment of breast cancer: an international team involving the Clinical Institute of Pathology at the MedUni Vienna has been able to demonstrate the activation of a receptor, the Ret protein (Rearranged during transfection), on the surface of breast cancer cells. Increased levels of this protein are associated with a lower likelihood of survival for breast cancer patients.

8 Aug 2013

Understanding the movement of neurons sheds light on how cancer cells invade health tissues

The invasion of brain-tumor cells into surrounding tissue requires the same protein molecule that neurons need to migrate into position as they differentiate and mature, according to new research from the University of Illinois at Chicago College of Medicine and published August 7 in the online journal PLOS ONE.

8 Aug 2013

Janssen receives EC approval to use VELCADE as induction therapy in patients with multiple myeloma

Janssen-Cilag International NV announced today that the European Commission has approved the use of VELCADE (bortezomib) as induction therapy (a first therapeutic option) in combination with dexamethasone or thalidomide and dexamethasone. This licence extension will apply to adult patients with previously-untreated multiple myeloma who are eligible for high-dose chemotherapy with haematological stem cell transplantation.

8 Aug 2013

Teachers eating lunch with school children offers opportunity of nutrition education

Much attention has focused on school meals, both in the United States and across the globe. Researchers at Uppsala University, Sweden, evaluated teachers eating lunch with the school children.

8 Aug 2013

ASU expert receives $1.6 million grant to advance microscopy imaging research

At Arizona State University's Biodesign Institute, Nongjian (NJ) Tao has been designing advanced microscopy methods with the ambitious aim of capturing molecular-scale phenomena in living systems. The new techniques, which combine multiple imaging modalities, are poised to revolutionize the study of biology and the development of new drugs.

8 Aug 2013

New bio-artificial "encapsulife" pancreas points to cure for diabetes

The Squash Diabetes Campaign, launched by the Georgetown University Women's Squash Team* in December 2012 and sponsored by New Generation Foundation, today announced a $125,000 grant provided by the Chicago-based Chauncey and Marion D. McCormick Family Foundation.

8 Aug 2013

Research suggests treadmill training after spinal cord injury can have positive effects on recovery

New research suggests that treadmill training soon after a spinal cord injury can have long-lasting positive effects on recovery - as long as the training is accompanied by efforts to control inflammation in the lower spinal cord.

8 Aug 2013

Research findings may give scientists a way to destroy cancerous cells

Researchers at Warwick Medical School have identified the key role played by a team of proteins in the process of mitosis. Working out how to control them may give scientists a way to destroy cancerous cells.

8 Aug 2013

Specific pattern in lung tumor pathology is strong predictor of recurrence, says study

A new study by thoracic surgeons and pathologists at Memorial Sloan-Kettering Cancer Center shows that a specific pattern found in the tumor pathology of some lung cancer patients is a strong predictor of recurrence.

8 Aug 2013

NCI renews UCLA prostate SPORE grant

UCLA's Jonsson Comprehensive Cancer Center and the department of urology at the David Geffen School of Medicine at UCLA have been notified that their standing as a National Cancer Institute Specialized Program of Research Excellence site in prostate cancer has been renewed for another five years.

8 Aug 2013

Moderate exercise could help guard against and treat tendon disease

Moderate exercise could be good for keeping your tendons healthy according to new research from the University of East Anglia funded by Arthritis Research UK.

8 Aug 2013

Researchers identify mechanism responsible for loss of tumor-suppressor gene in soft-tissue sarcomas

Researchers have discovered a novel mechanism responsible for the loss of a critical tumor-suppressor gene in rhabdomyosarcoma and other soft-tissue sarcomas, rare cancers that strike mainly children and often respond poorly to treatment. Their cause is largely unknown.

8 Aug 2013

TSRI scientists decode important molecular signal that guides development of neocortex

Scientists at The Scripps Research Institute have decoded an important molecular signal that guides the development of a key region of the brain known as the neocortex. The largest and most recently evolved region of the brain, the neocortex is particularly well developed in humans and is responsible for sensory processing, long-term memory, reasoning, complex muscle actions, consciousness and other functions.

8 Aug 2013

High-tech laser technique offers control of gene therapy and genetic engineering method

The applications of gene therapy and genetic engineering are broad: everything from pet fish that glow red to increased crop yields worldwide to cures for many of the diseases that plague humankind.

8 Aug 2013

Wiring diagram of retinal neurons: The first step toward mapping the human brain

The human brain has 100 billion neurons, connected to each other in networks that allow us to interpret the world around us, plan for the future, and control our actions and movements. MIT neuroscientist Sebastian Seung wants to map those networks, creating a wiring diagram of the brain that could help scientists learn how we each become our unique selves.

8 Aug 2013

Cell News and Research

High mobility group (HMG) genes and cancer: an interview with Dr. Linda Resar, Johns Hopkins University School of Medicine

Findings could lead to development of therapeutic agents for age-related diseases

Penn State researchers find that protein changes can control gene functions

Study finds no evidence that retired NFL players suffer chronic traumatic encephalopathy

Researchers unveil comprehensive portrait of the genome of world's first immortal cell line

Ret enzyme may be a novel therapeutic target in selected groups of breast cancer patients

Understanding the movement of neurons sheds light on how cancer cells invade health tissues

Janssen receives EC approval to use VELCADE as induction therapy in patients with multiple myeloma

Teachers eating lunch with school children offers opportunity of nutrition education

ASU expert receives $1.6 million grant to advance microscopy imaging research

New bio-artificial "encapsulife" pancreas points to cure for diabetes

Research suggests treadmill training after spinal cord injury can have positive effects on recovery

Research findings may give scientists a way to destroy cancerous cells

Specific pattern in lung tumor pathology is strong predictor of recurrence, says study

NCI renews UCLA prostate SPORE grant

Moderate exercise could help guard against and treat tendon disease

Researchers identify mechanism responsible for loss of tumor-suppressor gene in soft-tissue sarcomas

TSRI scientists decode important molecular signal that guides development of neocortex

High-tech laser technique offers control of gene therapy and genetic engineering method

Wiring diagram of retinal neurons: The first step toward mapping the human brain

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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