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Adaptimmune initiates Phase I/IIa open-label clinical trial in patients with ovarian cancer

Adaptimmune announced today that it has opened a Phase I/IIa, multiple-site, two-cohort, open-label clinical trial in ovarian cancer at Roswell Park Cancer Institute (RPCI) in Buffalo, N.Y., and City of Hope (COH) in Duarte, Calif.

26 Jul 2013

Takeda unbinds Phase 3 study of orteronel in patients with mCRPC that progressed post-chemotherapy

Takeda Pharmaceutical Company Limited ("Takeda") announced today that it has unblinded the ELM-PC 5 Phase 3 study (C21005) of orteronel plus prednisone compared to placebo plus prednisone in patients with metastatic, castration- resistant prostate cancer (mCRPC) that had progressed during or following chemotherapy based on the recommendation of the Independent Data Monitoring Committee (IDMC).

26 Jul 2013

Elsevier announces winner of first Netter Atlas Medical Illustration Contest

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced the winner of the first Netter Atlas Medical Illustration Contest.

26 Jul 2013

Non-invasive optical techniques use LED, laser to view beneath skin

Impressive examples of new non-invasive optical techniques using lasers, light-emitting diodes (LEDs), and spectroscopic methods to probe and render images from beneath the surface of the skin are featured in a newly completed special section in the Journal of Biomedical Optics published by SPIE, the international society for optics and photonics.

26 Jul 2013

Inner ear supporting cells protect hair cells by secreting HSP70

An underlying cause of hearing loss is the death of sensory hair cells in the inner ear, which can be damaged in response to a variety of factors including the use of aminoglycoside antibiotics.

26 Jul 2013

New technology enables all of the world's crops to take nitrogen from the air

A major new technology has been developed by The University of Nottingham, which enables all of the world's crops to take nitrogen from the air rather than expensive and environmentally damaging fertilisers.

26 Jul 2013

Alcohol Research Program at Loyola University receives four NIH grants totaling $3M dollars

The Alcohol Research Program at Loyola University Chicago Stritch School of Medicine recently received four research grants, totaling more than $3 million, from the National Institutes of Health.

26 Jul 2013

Finding could aid in delivering personalized cancer medicine based on individual's genetics

Scientists at the Princess Margaret Cancer Centre have discovered a function of the tumor suppressor gene PTEN that helps explain why certain promising therapies fail in many cancer patients, a finding that could aid in delivering tailored, personalized cancer medicine based on an individual's genetics.

26 Jul 2013

EGFR mutation testing dropped once funding from pharmaceutical industry discontinued

Significant advances have taken place in the management of patients with advanced and metastatic non-small-cell lung cancer over the last 5 years. Traditionally, all advanced NSCLC patients were treated in a similar manner.

26 Jul 2013

Researchers find how brain cells communicate with each other in different voice tones

Brain cells talk to each other in a variety of tones. Sometimes they speak loudly but other times struggle to be heard. For many years scientists have asked why and how brain cells change tones so frequently. Today National Institutes of Health researchers showed that brief bursts of chemical energy coming from rapidly moving power plants, called mitochondria, may tune brain cell communication.

26 Jul 2013

Supporting cells in the inner ear can help repair damaged sensory hair cells, say researchers

Researchers have found in mice that supporting cells in the inner ear, once thought to serve only a structural role, can actively help repair damaged sensory hair cells, the functional cells that turn vibrations into the electrical signals that the brain recognizes as sound.

26 Jul 2013

Researchers explore impact of obesity on outcomes of patients with advanced non-small cell lung cancer

Obesity increases health risks for many things. Researchers wanted to know the impact of obesity on outcomes of patients with advanced non-small cell lung cancer. In the September issue of the International Association for the Study of Lung Cancer's journal, the Journal of Thoracic Oncology, researchers conclude that obese patients had superior outcomes early on in the study, but then experienced increased hazards.

26 Jul 2013

EPHB2 overexpressed in malignant pleural mesothelioma cell lines, find researchers

Malignant mesothelioma is a rare asbestos-associated malignancy with limited therapeutic options. Despite advances in the treatment, the median survival remains 12 months from the time of diagnosis. Increased understanding of the molecular basis for the diverse signaling pathways involved in cancer progression should promote the discovery of novel biomarkers for early diagnosis and potentially lead to more effective therapeutic tools for the disease.

26 Jul 2013

Novo Solutions MD announces releases of NovoScarMD scar cream

Novo Solutions MD announces the launch of NovoScarMD the most scientifically advanced scar cream to come to market in 10 years. NovoScarMD reverses existing and new scar damage, keloids, and stretch marks, and rapidly returns skin to its original state with almost no trace of skin injury

25 Jul 2013

Teva, Lonza decide to discontinue biosimilars collaboration

Teva Pharmaceutical Industries and Lonza Group today announced that following a strategic review of the Teva-Lonza Joint Venture (TL-JV), the companies have decided to discontinue their collaboration for the development, manufacturing and marketing of biosimilars.

25 Jul 2013

NOXXON completes patient recruitment of NOX-E36 Phase IIa trial for treatment of diabetic nephropathy

NOXXON Pharma today announced the successful completion of patient recruitment of its NOX-E36 Phase IIa clinical trial for the treatment of diabetic nephropathy. NOX-E36 is a Spiegelmer® that binds and neutralizes CCL2/MCP-1 (C-C Chemokine Ligand / Monocyte Chemoattractant Protein-1), a pro-inflammatory chemokine that plays an important role in the progression of diabetic nephropathy, the most common single cause of chronic kidney failure and end-stage renal disease.

25 Jul 2013

Researchers to study knowledge and satisfaction of women who choose DNA prenatal screening test

A recently available DNA-based prenatal blood test used to screen pregnancies for Down syndrome and similar chromosome abnormalities in high-risk women is moving a step closer to use in the general pregnancy population.

From Natera 25 Jul 2013

Study may lead to personalized treatments for mitochondrial energy disorders

Researchers have identified a master network of signaling molecules that acts like a "fuse box" to regulate the cellular effects of defective energy flow in mitochondrial respiratory chain diseases—a diverse set of difficult-to-treat genetic-based energy disorders.

25 Jul 2013

Discovery points to new therapeutic strategy for Parkinson's disease

Biologists at The Scripps Research Institute have made a significant discovery that could lead to a new therapeutic strategy for Parkinson's disease.

25 Jul 2013

PerkinElmer enhances Operetta imaging system to perform live cell assays with higher throughput

PerkinElmer, Inc., a global leader focused on the health and safety of people and the environment, has announced enhancements for its Operetta® High Content Imaging System, designed to significantly improve the ability of scientists to perform live cell assays with higher throughput, to help foster a better understanding of normal and aberrant cellular behavior.

25 Jul 2013

Cell News and Research

Adaptimmune initiates Phase I/IIa open-label clinical trial in patients with ovarian cancer

Takeda unbinds Phase 3 study of orteronel in patients with mCRPC that progressed post-chemotherapy

Elsevier announces winner of first Netter Atlas Medical Illustration Contest

Non-invasive optical techniques use LED, laser to view beneath skin

Inner ear supporting cells protect hair cells by secreting HSP70

New technology enables all of the world's crops to take nitrogen from the air

Alcohol Research Program at Loyola University receives four NIH grants totaling $3M dollars

Finding could aid in delivering personalized cancer medicine based on individual's genetics

EGFR mutation testing dropped once funding from pharmaceutical industry discontinued

Researchers find how brain cells communicate with each other in different voice tones

Supporting cells in the inner ear can help repair damaged sensory hair cells, say researchers

Researchers explore impact of obesity on outcomes of patients with advanced non-small cell lung cancer

EPHB2 overexpressed in malignant pleural mesothelioma cell lines, find researchers

Novo Solutions MD announces releases of NovoScarMD scar cream

Teva, Lonza decide to discontinue biosimilars collaboration

NOXXON completes patient recruitment of NOX-E36 Phase IIa trial for treatment of diabetic nephropathy

Researchers to study knowledge and satisfaction of women who choose DNA prenatal screening test

Study may lead to personalized treatments for mitochondrial energy disorders

Discovery points to new therapeutic strategy for Parkinson's disease

PerkinElmer enhances Operetta imaging system to perform live cell assays with higher throughput

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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