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Bioniche, Paladin close debt refinancing agreement and sign first licensing deal for Urocidin

Bioniche Life Sciences Inc. and Paladin Labs Inc. today announced the official closing of the various agreements associated with a comprehensive strategic collaboration to refinance and increase Bioniche's debt, provide new equity, and enter into the first licensing deal for Bioniche's Phase III bladder cancer product - Urocidin.

6 Jul 2013

Researchers are a step closer to producing stem cells for research and therapy

A team of Toronto-based researchers may be one step closer to a 'recipe' for large-scale production of stem cells for use in research and therapy.

6 Jul 2013

Seattle researchers map critical molecules that regulate inflammation during flu infection

The influenza virus' ability to mutate quickly has produced new, emerging strains that make drug discovery more critical than ever. For the first time, researchers at Seattle BioMed, along with collaborators at the University of California, San Diego School of Medicine, St. Jude Children's Research Hospital and the University of Washington, have mapped how critical molecules regulate both the induction and resolution of inflammation during flu infection.

6 Jul 2013

Study describes how human mammary gland becomes highly sensitive to insulin during lactation

Why do so many mothers have difficulty making enough milk to breastfeed? A new study by scientists at Cincinnati Children's Hospital Medical Center and the University of California Davis adds to their previous research implicating insulin's role in lactation success.

6 Jul 2013

Scientists focus on the role of mutated adult neural stem cells play in human diseases

CHARGE syndrome* is a severe developmental disorder affecting multiple organs. It affects 1 in 8500 newborns worldwide. The majority of patients carry a mutation in a gene called CHD7. How this single mutation leads to the broad spectrum of characteristic CHARGE symptoms has been a mystery.

6 Jul 2013

Epigenome mapping uncovers unique patterns that emerge during generation of brain circuitry

High-resolution mapping of the epigenome has discovered unique patterns that emerge during the generation of brain circuitry in childhood.

6 Jul 2013

Research shows gene regulatory sequences may have driven the evolution of human limbs

Thousands of sequences that control genes are active in the developing human limb and may have driven the evolution of the human hand and foot, a comparative genomics study led by Yale School of Medicine researchers has found.

5 Jul 2013

Researchers develop new tool to promote improved drug development

Researchers at Karolinska Institutet in Sweden have developed the first method for directly measuring the extent to which drugs reach their targets in the cell.

5 Jul 2013

Findings uncover epigenomic modification that occurs during brain formation

Changes in the epigenome, including chemical modifications of DNA, can act as an extra layer of information in the genome, and are thought to play a role in learning and memory, as well as in age-related cognitive decline.

5 Jul 2013

Research: People's frontal cortex undergoes a significant change from infancy to adolescence

Experience of parents with their children and teachers with their students demonstrate how kids change their behaviours and knowledge from infancy to adolescence. Until now, little was known of the causes that could lead to these changes.

5 Jul 2013

Researchers identify role of Nanog gene in embryonic stem cell differentiation

Whitehead Institute researchers have determined that the transcription factor Nanog, which plays a critical role in the self-renewal of embryonic stem cells, is expressed in a manner similar to other pluripotency markers.

4 Jul 2013

Genetic cause identified for diffuse non-epidermolytic palmoplantar keratoderma

Scientists have identified the genetic cause of a rare skin condition that causes the hands and feet to turn white and spongy when exposed to water.

4 Jul 2013

Study on assisted reproduction published in Reproductive BioMedicine Online

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced the publication of a recent retrospective study in Reproductive BioMedicine Online to better understand treatment considerations and outcomes for same-sex male couples and single men when using assisted reproduction treatment.

4 Jul 2013

New research shows that exercise changes expression of innate DNA

Exercise, even in small doses, changes the expression of our innate DNA. New research from Lund University in Sweden has described for the first time what happens on an epigenetic level in fat cells when we undertake physical activity.

4 Jul 2013

Saltwater-treatment for cystic fibrosis: an interview with Matthew Allen, Program Director at Cambridge Consultants

A group of Australian researchers, back in 2006, noted that there was a link between the severity of cystic fibrosis between sufferers who surfed, and sufferers who did not surf – and obviously Australia is a good place to spot that.

4 Jul 2013

New study finds inherited genetic contribution in autism with intellectual disability

Researchers are striving to understand the different genetic structures that underlie at least a subset of autism spectrum disorders. In cases where the genetic code is in error, did that happen anew in the patient, perhaps through mutation or copying error, or was it inherited? A new study in the American Journal of Human Genetics finds evidence that there may often be a recessive, inherited genetic contribution in autism with significant intellectual disability.

4 Jul 2013

Roche introduces new metabolite tests for cell fermentation analytics

Roche today announced the launch of new metabolite-testing reagent sets to determine the concentration of iron and phosphate, two parameters relevant for cell growth and productivity during fermentation processes.

4 Jul 2013

Study shows possible biological cause of narcolepsy

In 2000, researchers at the UCLA Center for Sleep Research published findings showing that people suffering from narcolepsy, a disorder characterized by uncontrollable periods of deep sleep, had 90 percent fewer neurons containing the neuropeptide hypocretin in their brains than healthy people.

4 Jul 2013

Research shows mutations in FAM190A gene may contribute to chromosomal instability in cancer

Johns Hopkins cancer scientists have discovered that a little-described gene known as FAM190A plays a subtle but critical role in regulating the normal cell division process known as mitosis, and the scientists' research suggests that mutations in the gene may contribute to commonly found chromosomal instability in cancer.

4 Jul 2013

MGN1703 drug provides a new treatment approach to colorectal cancer

New data on an emerging treatment that aims to fight colorectal cancer by stimulating the immune system have been presented at the ESMO 15th World Congress on Gastrointestinal Cancer.

4 Jul 2013

Cell News and Research

Bioniche, Paladin close debt refinancing agreement and sign first licensing deal for Urocidin

Researchers are a step closer to producing stem cells for research and therapy

Seattle researchers map critical molecules that regulate inflammation during flu infection

Study describes how human mammary gland becomes highly sensitive to insulin during lactation

Scientists focus on the role of mutated adult neural stem cells play in human diseases

Epigenome mapping uncovers unique patterns that emerge during generation of brain circuitry

Research shows gene regulatory sequences may have driven the evolution of human limbs

Researchers develop new tool to promote improved drug development

Findings uncover epigenomic modification that occurs during brain formation

Research: People's frontal cortex undergoes a significant change from infancy to adolescence

Researchers identify role of Nanog gene in embryonic stem cell differentiation

Genetic cause identified for diffuse non-epidermolytic palmoplantar keratoderma

Study on assisted reproduction published in Reproductive BioMedicine Online

New research shows that exercise changes expression of innate DNA

Saltwater-treatment for cystic fibrosis: an interview with Matthew Allen, Program Director at Cambridge Consultants

New study finds inherited genetic contribution in autism with intellectual disability

Roche introduces new metabolite tests for cell fermentation analytics

Study shows possible biological cause of narcolepsy

Research shows mutations in FAM190A gene may contribute to chromosomal instability in cancer

MGN1703 drug provides a new treatment approach to colorectal cancer

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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