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A drug derived from an ocean-growing sponge helps prevent the growth of cancer cells

A drug derived from an ocean-growing sponge teams up to enhance the performance of the yew tree derivative Taxol® (paclitaxel) in preventing the growth of cancer cells, according to research published in the July 15 issue of the journal Cancer Research.

15 Jul 2004

Research that directs cancer-killing immune cells against the deadliest brain tumors shows promise

Researchers seeking to direct cancer-killing immune cells against the deadliest brain tumors have three new targets that show promise in laboratory studies and in a Phase I patient trial, according to two articles in the July 15 issue of the journal Cancer Research.

15 Jul 2004

Important milestone for any cancer therapy that will be useful for treating patients

Mayo Clinic researchers have manipulated a human antibody to induce an anti-tumor response in living mice that consistently curbs - and often cures - malignant melanoma, one of the most lethal forms of skin cancer and the most common cancer of young adults.

15 Jul 2004

Latest findings on HIV pathogenesis at AIDS Conference in Bangkok

At the XVth International AIDS Conference in Bangkok, Thailand, Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases and chief of the NIAID Laboratory of Immunoregulation (LIR), will present his laboratory’s latest findings on how aberrant immune activation underlies HIV pathogenesis.

15 Jul 2004

Research may help predict risk for prostate cancer based on gene expression patterns

According to a study published in the July 15 issue of the Journal of Clinical Oncology, genes expressed in benign tissue adjacent to prostate cancer tissue are much more similar to those expressed in prostate cancer tissue than previously thought.

15 Jul 2004

Immunotherapeutic strategy allowing patients to use their own immune system to fight their cancer

Scientists affiliated with the Harvard University Medical School have devised ways of bolstering patients' immune response against kidney and breast cancer.

15 Jul 2004

Dietary niacin may protect against the development of Alzheimer's disease

Dietary niacin (vitamin B3 ) may protect against the development of Alzheimer's disease and the cognitive decline associated with ageing in older people, suggests research in the Journal of Neurology Neurosurgery and Psychiatry.

15 Jul 2004

Thalidomide's role in fighting blood disorders, such as multiple myeloma

From the late 1950s to the end of 1961, thalidomide was a popular sedative and treatment for morning sickness until it was discovered to cause fetal malformations, which proved fatal within the first year of life in 40 percent of affected infants.

13 Jul 2004

New hereditary spastic paraplegia research

In work reported this week, researchers have taken our understanding of HSP to a new level with the development of an animal model for the disease.

13 Jul 2004

Research provides new insight into the carefully controlled architectural changes that underlie organ development

A new research study demonstrates that a single chemical growth factor orchestrates a complex developmental process by sequentially activating distinct subsets of molecular signals.

13 Jul 2004

Molecular mechanisms behind XsalF's anterior specifying activity

Embryologists have long been interested in working out the means by which this regionalization is achieved, and for years the dominant theory has involved a two-step mechanism in which neural tissues are first induced lengthwise down the entire body axis, followed by a transformation step where a second signal specifies the posterior identities of the neural tissue

13 Jul 2004

Congenital heart disease (CHD) is a leading cause of mortality in children worldwide

Congenital heart disease (CHD) is a leading cause of mortality in children worldwide. According to the American Heart Association, Congenital cardiovascular defects are present in about one percent of live births and are the most common malformations in newborns.

12 Jul 2004

Cell Therapeutics receives Fast Track Designation for Pixantrone, treatment for aggressive non-Hodgkin's lymphoma

Cell Therapeutics, Inc. has received fast track designation from the U.S. Food and Drug Administration (FDA) for pixantrone, a novel anthracenedione, being investigated for the potential treatment of relapsed, aggressive non-Hodgkin's lymphoma (NHL).

12 Jul 2004

Study evaluates effectiveness of LEXIVA/ritonavir and Lopinavir/ritonavir in protease inhibitor

HIV treatment regimens containing the protease inhibitor (PI) LEXIVA® (fosamprenavir calcium) dosed with ritonavir (LEXIVA/r) or lopinavir (LPV) and ritonavir (LPV/r) were effective in suppressing HIV in patients who had failed prior PI-containing regimens, according to information presented at the International AIDS Conference (IAC).

12 Jul 2004

Increasing evidence a virus may play a role in breast cancer

A new study finds increasing evidence a virus may play a role in breast cancer. The study finds nearly three-quarters of a small sample of Tunisian breast cancer patients showed evidence of a virus similar to one known to cause breast cancer in mice, twice the rate seen in women in the United States.

12 Jul 2004

Evidence that new anti-inflammatory drug may sensitize leukemia, and breast and lung cancers to conventional chemotherapy

Ohio researchers have used a recently developed anti-inflammatory drug as a starting point to construct a possible new, targeted anti-cancer agent.

10 Jul 2004

First successful gene therapy that mimics the action of calcium channel blockers

Their findings - published in the latest edition of Circulation Research, online July 8 - may lead to a gene therapy alternative to calcium channel blockers and their sometimes severe side effects, but also further interest in the development of gene therapies unique - as in this case - to one particular organ.

10 Jul 2004

Cell News and Research

A drug derived from an ocean-growing sponge helps prevent the growth of cancer cells

Research that directs cancer-killing immune cells against the deadliest brain tumors shows promise

Important milestone for any cancer therapy that will be useful for treating patients

Latest findings on HIV pathogenesis at AIDS Conference in Bangkok

Research may help predict risk for prostate cancer based on gene expression patterns

Immunotherapeutic strategy allowing patients to use their own immune system to fight their cancer

Dietary niacin may protect against the development of Alzheimer's disease

Thalidomide's role in fighting blood disorders, such as multiple myeloma

New hereditary spastic paraplegia research

Research provides new insight into the carefully controlled architectural changes that underlie organ development

Molecular mechanisms behind XsalF's anterior specifying activity

Congenital heart disease (CHD) is a leading cause of mortality in children worldwide

Cell Therapeutics receives Fast Track Designation for Pixantrone, treatment for aggressive non-Hodgkin's lymphoma

Study evaluates effectiveness of LEXIVA/ritonavir and Lopinavir/ritonavir in protease inhibitor

Increasing evidence a virus may play a role in breast cancer

Evidence that new anti-inflammatory drug may sensitize leukemia, and breast and lung cancers to conventional chemotherapy

First successful gene therapy that mimics the action of calcium channel blockers

The structure of AGT shows how one human protein reduces the potency of chemotherapy

Anal cancer is on the rise in both sexes

Possible cure for sudden infant death syndrome (SIDS)

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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