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Study reveals a 'stealing' mechanism that contributes to antibody diversity

A few years ago, Professor Kathrin de la Rosa and her colleagues in the lab of the Swiss immunologist Antonio Lanzavecchia made an unusual discovery.

29 Aug 2022

Intracellular bacteria protect their host against giant viruses, research shows

Amoebae receive surprising support in defense against viruses: The bacteria they are infected with prevent them from being destroyed by giant viruses.

29 Aug 2022

UAB researchers report a potential treatment for ARID1A-deficient bladder cancer

Metastatic bladder cancer is generally incurable, so new therapies are an urgent need. Researchers at the University of Alabama at Birmingham now report a potential treatment for a quarter of bladder cancers.

4 Aug 2022

Scientists find new evidence against using BET inhibitors to treat COVID-19

A while ago, some researchers had suggested that blocking a set of proteins, known as bromodomain and extraterminal (BET) proteins, might be a way to fight COVID-19.

20 Jul 2022

Research describes one of the ways the SARS-CoV-2 virus recruits cells to replicate

An article published in the journal Frontiers in Cellular and Infection Microbiology reports a study by researchers at the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil showing how a human protein interacts with a SARS-CoV-2 protein, and describing one of the ways the virus that causes COVID-19 recruits cells to replicate.

18 Jul 2022

Beyond COVID-19: the potential future applications of mRNA vaccines

Researchers described the production, mechanisms, and potential applications of mRNA vaccines.

6 Jul 2022

Study of condensates offers new hope for the treatment of neurodegenerative diseases

The Körber European Science Prize 2022, endowed with one million euros, is to be awarded to the British cell biologist Anthony Hyman.

30 Jun 2022

UTSW study provides a potential avenue for the development of new antivirals against influenza

A collaborative study from UT Southwestern scientists has identified a new function for a protein called TAO2 that appears to be key to inhibiting replication of the influenza virus, which sickens millions of individuals worldwide each year and kills hundreds of thousands.

20 Jun 2022

New findings reveal potential mechanisms for cellular defects in human laminopathies

A Northwestern Medicine study has uncovered distinct roles for major nuclear lamin isoforms in maintaining intracellular interactions and cellular mechanics, according to findings published in the Proceedings of the National Academy of Sciences.

1 Jun 2022

NYU Abu Dhabi research could pave the way for more effective cancer treatments

A team led by Professor of Biology, Senior Vice Provost of Research at NYU Abu Dhabi, and UAE national Sehamuddin Galadari, has discovered a novel structural modification in AMP-activated protein kinase (AMPK) during anticancer therapy that could pave the way for the development of more effective cancer treatments.

25 May 2022

Review portrays clinical journey of messenger RNA vaccines and mRNA-based therapies

Researchers reviewed messenger ribonucleic acid (mRNA) technology and highlighted its clinical applications.

11 May 2022

Investigating the role of cyclins and cyclin-dependent kinases in host restriction of SARS-CoV-2 infection

Researchers investigated COVID-19-triggered changes in the levels of cyclins and cyclin-dependent kinases inside host cells.

10 May 2022

Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

My work is focused on looking at the dynamics of B/T cell populations within lymph nodes from patients that had recovered from COVID-19. My role in this research was developing and implementing microscopy image analysis techniques using methods and instrumentation in part supplied by TissueGnostics.

From TissueGnostics 26 Apr 2022

Cell division crucial for the success of macrophage infiltration

Researchers at ISTA discover a crucial process that enables immune cells to get to where they are needed. Study published in Science.

21 Apr 2022

Regulation of alternative splicing goes haywire in cells of a newly formed embryo

Alternative splicing is a fundamental biological process that allows cells to make many different types of mRNAs and proteins from a limited number of genes. For many animals, including humans, it is a feature that is essential for the development of complex cells such as muscles or neurons.

13 Apr 2022

Researchers elucidate how ovarian tumors defy immunotherapy

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health, with collaborators at La Jolla Institute for Immunology and elsewhere, have further elucidated how ovarian cancer tumors defy immunotherapy, identifying new molecular targets that might boost immune response.

12 Apr 2022

Effect of COVID-19 mRNA vaccine on in vitro glial cells of the brain studied by Raman spectroscopy and imaging

Researchers studied how the mRNA-based BNT162b2 COVID-19 vaccine altered the biochemical composition of glial and glioma brain cells in vitro.

8 Mar 2022

Researchers discover a nuclear import mechanism essential for organ growth and development

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified a nuclear import mechanism essential for organ growth and development. Manipulation of this mechanism has potential applications in the control of organ growth and organ regeneration.

4 Mar 2022

Using interdisciplinary approach to beat cancer

European Cooperation in Science and Technology (COST) World Cancer Day aims at raising awareness of cancer and to encourage its prevention, detection, and treatment.

4 Feb 2022

Study offers unprecedented insight into the mechanism of action of topo VI enzyme

The function of an enzyme, critical to most forms of life, has been revealed.

2 Feb 2022