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Single protein plays a major role in prion diseases

A single protein plays a major role in deadly prion diseases by smashing up clusters of these infectious proteins, creating the "seeds" that allow fatal brain illnesses to quickly spread, new Brown University research shows.

23 Jan 2007

Variations in SORL1 gene may factor in development of Alzheimer's disease

Variations in a gene known as SORL1 may be a factor in the development of late onset Alzheimer's disease, an international team of researchers has discovered. The genetic clue, which could lead to a better understanding of one cause of Alzheimer's, is reported in Nature Genetics online, and was supported in part by the National Institutes of Health (NIH).

14 Jan 2007

Enzyme PMR1 reveals kind side

New research shows that a recently discovered enzyme that destroys the messenger RNA (mRNA) for some proteins can also help to protect the mRNA during times of stress. The response might help cancer cells survive chemotherapy and radiation therapy.

10 Jan 2007

Uric acid holds potential for central nervous system damage

Uric acid is commonly associated with the excruciatingly painful joint disease known as gout, but it can also play a crucial role in the treatment of spinal cord injury and other central nervous system disorders, such as stroke, multiple sclerosis and Parkinson's disease, according to Rutgers' Bonnie Firestein.

3 Jan 2007

Mifepristone offers hope for breast cancer victims

A team of scientists have discovered some unexpected benefits with the abortion pill RU486 (Mifepristone).

4 Dec 2006

Scientists explain how transport proteins can move in cells without bumping into or sticking to anything

Scientists from the Max Planck Institute for Molecular Cell Biology and Genetics (MPI-CBG) in Dresden, along with a colleague from the University of Florida in the United States, have been carrying out research into how transport proteins can move in cells without bumping into or sticking to anything.

24 Oct 2006

Scientists discover how brain turns on system designed to protect nerve cells from toxic "free radicals"

Scientists at Dana-Farber Cancer Institute report they have found how the brain turns on a system designed to protect its nerve cells from toxic "free radicals," a waste product of cell metabolism that has been implicated in some degenerative brain diseases, heart attacks, strokes, cancer, and aging.

20 Oct 2006

Blood clotting protein appears to also play a role in fertility

A protein known to play a role in blood clotting and other cell functions is also critical for proper sperm formation in mice, according to researchers from the University of North Carolina at Chapel Hill School of Medicine.

20 Oct 2006

Why organs fail following massive trauma

Massive trauma, say from a sabertooth tiger attack, meant immediate death for the primitive human.

17 Oct 2006

Researchers identify cell line that is resistant to retroviruses

Researchers at the University of Minnesota have identified a protein that enables viruses such as HIV to infect cells and spread through the body.

17 Oct 2006

Direct observations of DNA provides new insights into how genetic material is copied and repaired

"We can monitor the process directly, and that gives us a different perspective," said Roberto Galletto, a postdoctoral scholar at UC Davis and first author on a paper published Sept. 20 on the Web site of the journal Nature.

21 Sep 2006

p120 catenin protein can stop metastasis or promote it

A protein known to be a key component of the glue that holds cells together also is involved in breaking them apart and promoting their movement when tumors begin to spread to other parts of the body, researchers at Mayo Clinic have found.

20 Sep 2006

Researchers discover clues to the cause of T-cell acute lymphoblastic leukemia

Researchers' discovery of clues to the cause of T-cell acute lymphoblastic leukemia (T-ALL) - a form of pediatric cancer that has a very poor prognosis - could lead to the development of new targeted therapies for this extremely difficult disease.

20 Sep 2006

Regenerative Medicine wins award for best new journal

The journal Regenerative Medicine has been recognized by The Association of Learned and Professional Society Publishers as joint winner of the 2006 ALPSP/Charlesworth Award for Best New Journal. This prestigious international award is presented annually to the best new journal across a wide range of disciplines.

20 Sep 2006

Fat droplets play protective role inside cells

Too much body fat may be a bad thing, but there is increasing evidence that too little fat also may have some surprisingly negative consequences.

19 Sep 2006

Curcumin useful in the fight against colorectal cancer

Looking for a cancer cure? Try the spice rack. In the last few years, that tactic has proved productive for researchers investigating turmeric, a curry spice used for centuries in Indian traditional medicine.

19 Sep 2006

Chemotherapy, nutrition and metallic flavors

About two million cancer patients currently receiving certain drug therapies and chemotherapy find foods and beverages to have a foul metallic flavor, according to a medical study. In general, more than 40 percent of hospitalized patients suffer from malnutrition due to taste and smell dysfunction.

19 Sep 2006