Chagas Disease News and Research

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Chagas (pronounced SHA-gus) disease is named after the Brazilian physician Carlos Chagas, who discovered it in 1909. It is caused by the parasite Trypanosoma cruzi, which is transmitted to animals and people by insect vectors that are found only in the Americas (mainly, in rural areas of Latin America where poverty is widespread). Chagas disease (T. cruzi infection) is also referred to as American trypanosomiasis.

People can become infected in various ways. In Chagas-endemic areas, the main way is through vectorborne transmission. The insect vectors are called triatomine bugs. These blood-sucking bugs get infected by biting an infected animal or person. Once infected, the bugs pass T. cruzi parasites in their feces. The bugs are found in houses made from materials such as mud, adobe, straw, and palm thatch. During the day, the bugs hide in crevices in the walls and roofs. During the night, when the inhabitants are sleeping, the bugs emerge. Because they tend to feed on people’s faces, triatomine bugs are also known as “kissing bugs.” After they bite and ingest blood, they defecate on the person. The person can become infected if T. cruzi parasites in the bug feces enter the body through mucous membranes or breaks in the skin. The unsuspecting, sleeping person may accidentally scratch or rub the feces into the bite wound, eyes, or mouth.
Researchers prove that CD27 drug is true alternative against malaria

Researchers prove that CD27 drug is true alternative against malaria

Wild fleas transmit Chagas' disease in some regions of Latin America

Wild fleas transmit Chagas' disease in some regions of Latin America

Melanoma in adulthood can be reduced by consistent use of sunscreen in childhood

Melanoma in adulthood can be reduced by consistent use of sunscreen in childhood

Researchers develop new method for isolating, genome sequencing individual malaria parasite cell

Researchers develop new method for isolating, genome sequencing individual malaria parasite cell

GHIT Fund announces grants to speed up innovative drug development for neglected diseases

GHIT Fund announces grants to speed up innovative drug development for neglected diseases

Scientist receives $147,157 grant from NIH to find cure for infectious disease

Scientist receives $147,157 grant from NIH to find cure for infectious disease

A-PARADDISE consortium obtains funds to develop innovative therapies for neglected parasitic diseases

A-PARADDISE consortium obtains funds to develop innovative therapies for neglected parasitic diseases

Researchers develop a class of compounds that may help eradicate Chagas disease

Researchers develop a class of compounds that may help eradicate Chagas disease

New tools for neglected diseases: an interview with Dr. BT Slingsby, CEO, GHIT Fund

New tools for neglected diseases: an interview with Dr. BT Slingsby, CEO, GHIT Fund

PLOS and DNDi to launch collection of neglected tropical diseases at 10-year anniversary of DNDi

PLOS and DNDi to launch collection of neglected tropical diseases at 10-year anniversary of DNDi

New paper highlights correlations between changes in natural systems and potential health outcomes

New paper highlights correlations between changes in natural systems and potential health outcomes

GHIT Fund makes new investments in potential treatments for malaria, tuberculosis and Chagas disease

GHIT Fund makes new investments in potential treatments for malaria, tuberculosis and Chagas disease

GHIT Fund grants US$5.7 million to six global partnerships working on vaccines against malaria

GHIT Fund grants US$5.7 million to six global partnerships working on vaccines against malaria

Study finds persistent deficiency in new therapeutics for neglected diseases

Study finds persistent deficiency in new therapeutics for neglected diseases

University of Warwick professor wins Discovery STAR Award to identify new treatment for Chagas disease

University of Warwick professor wins Discovery STAR Award to identify new treatment for Chagas disease

DFID awards 5-year grant to DNDi to advance research and development for neglected diseases

DFID awards 5-year grant to DNDi to advance research and development for neglected diseases

Immunetics receives FDA clearance for BacTx rapid test for bacteria in apheresis platelets

Immunetics receives FDA clearance for BacTx rapid test for bacteria in apheresis platelets

DNDi and Institut Pasteur Korea collaborates to spur fight against neglected diseases

DNDi and Institut Pasteur Korea collaborates to spur fight against neglected diseases

WHO includes new paediatric therapeutic options to EMLc

WHO includes new paediatric therapeutic options to EMLc

WHO's new HIV treatment guidelines call for immediate ART for HIV-infected children

WHO's new HIV treatment guidelines call for immediate ART for HIV-infected children

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