Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Vit D deficiency does not raise stroke risk in African-Americans

While vitamin D deficiency is associated with fatal stroke among whites, it is not linked to more stroke deaths among blacks, according to research presented at the American Heart Association's Scientific Sessions 2010.

15 Nov 2010

Job strain can increase risk of cardiovascular disease in women

Women who report having high job strain have a 40 percent increased risk of cardiovascular disease, including heart attacks and the need for procedures to open blocked arteries, compared to those with low job strain, according to research presented at the American Heart Association's Scientific Sessions 2010.

14 Nov 2010

People with anxiety disorders require additional cardiac test: Study

People affected by anxiety and depression should receive an additional cardiac test when undergoing diagnosis for potential heart problems, according to a new study from Concordia University, the Universit- du Qu-bec - Montr-al and the Montreal Heart Institute.

12 Nov 2010

ASN Annual Meeting to highlight six late-breaking clinical trials on nephrology

Six late-breaking clinical trials have been accepted for presentation next week during the American Society of Nephrology's 43rd Annual Meeting and Scientific Exposition in Denver, CO. These trials were selected based upon their potential impact to the field of nephrology.

12 Nov 2010

Think treatments for cancer, diabetes don't grow on trees? Think again

Supported by thousands of years of use, a new wave of polymolecular botanical drugs (PBDs), backed by strong biomedical research and clinical trials, are growing in acceptance as a viable new drug category for the treatment and prevention of a wide spectrum of diseases from cancer to obesity.

11 Nov 2010

ESC emphasizes simple measures for diabetic patients to slow-down CVD progression

Diabetics can face a five times increase in the risk of developing cardiovascular disease (CVD) than non-diabetics. This leads to a seven to ten year reduction in life expectancy and a higher probability of suffering a fatal heart attack. These sad statistics have prompted the European Society of Cardiology (ESC) to mark World Diabetes Day on 14 November 2010 by emphasising the simple measures that diabetes patients should adopt to slow-down the progression of CVD and greatly improve their quality of life.

11 Nov 2010

High cholesterol in midlife does not increase risk for Alzheimer's disease among women

High cholesterol levels in middle age do not appear to increase women's risk of developing Alzheimer's disease and other forms of dementia later in life, new Johns Hopkins-led research finds, despite a body of scientific evidence long suggesting a link between the two.

11 Nov 2010

Mother's poor nutrition during pregnancy affects offspring's ability to process medications

New research has found that a mother's poor nutrition during pregnancy and nursing can cause problems for her offspring's ability to process medications, even well into adulthood.

11 Nov 2010

Study suggests mid-life cholesterol level may not linked to later development of Alzheimer's disease

Contrary to earlier research, a new, long-term study suggests that cholesterol level in mid-life may not be linked to later development of Alzheimer's disease, according to a study published in the November 10, 2010, online issue of Neurology, the medical journal of the American Academy of Neurology. However, the results suggest that large decreases in cholesterol levels in old age could be a better predictor of developing the memory-robbing disease.

11 Nov 2010

Statins benefit ‘at risk’ patients but are underused: Study

A look at some of the large clinical trials and studies has shown that thousands of deaths could be prevented a year if people at risk of heart attack or stroke are prescribed high doses of statins. The review involves data from 170,000 patients in 26 randomized trials. The paper is published in the journal The Lancet.

10 Nov 2010

Long-term use of statins unlikely to substantially increase overall cancer risk: Study

Researchers have further established that long-term use of statins is unlikely to substantially increase or decrease overall cancer risk, according to study results presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held Nov. 7-10, 2010, in Philadelphia.

10 Nov 2010

Researchers study drug's ability to restore retinal health in eyes of diabetic patients

One drug's startling ability to restore retinal health in the eyes of diabetic mice has researchers wanting to learn more about how it works and whether it might do the same for people.

10 Nov 2010

Researchers to determine levels of stroke risk in patients with narrowed brain arteries

Neurological researchers at Rush University Medical Center are part of a multicenter, National Institutes of Health (NIH) study to determine the levels of stroke risk and stroke recurrence in patients with narrowed brain arteries.

10 Nov 2010

BioInvent receives FDA IND clearance for BI-204 Phase II trial in cardiovascular disease

BioInvent International AB today announces IND clearance from the U.S. Food & Drug Administration (FDA) to initiate a Phase II study for BI-204. BI-204 is a human monoclonal antibody that specifically targets oxidized forms of a low-density lipoprotein (LDL) which has been linked to increased inflammatory processes leading to plaque formation in the blood vessel walls. BI-204 is being co-developed with Genentech for secondary prevention of cardiovascular events in patients with acute coronary syndrome (ACS).

10 Nov 2010

Study demonstrates preventive effect of urate lowering therapy on cardiovascular mortality

The use of urate lowering therapy might successfully prevent death from cardiovascular disease in people with gout, according to research presented at the Nov 2010, American College of Rheumatology Annual Scientific Meeting in Atlanta.

9 Nov 2010

Arena and Eisai report positive results from lorcaserin BLOOM-DM trial in obese, overweight diabetics

Arena Pharmaceuticals, Inc. and Eisai Inc. reported today that top-line results from the one-year lorcaserin BLOOM-DM trial demonstrate statistically significant weight loss in obese and overweight patients with type 2 diabetes. In this trial, lorcaserin met all three co-primary efficacy endpoints. In addition, as described below, lorcaserin patients taking lorcaserin 10 mg twice daily (BID) achieved statistically significant improvements in multiple secondary endpoints, including HbA1c, as compared to patients randomized to placebo.

9 Nov 2010

ORAL Solo Phase 3 study shows tasocitinib reduces signs and symptoms of active RA

Pfizer Inc. today announced results of ORAL Solo (1045), a Phase 3 study that showed tasocitinib (CP-690,550), an investigational, novel, oral JAK inhibitor, administered as monotherapy met two primary endpoints, demonstrating a statistically significant reduction in signs and symptoms of moderately to severely active rheumatoid arthritis (RA) and improvement in physical function as measured by ACR20 response rates and mean change in HAQ-DI, respectively, versus placebo at three months.

9 Nov 2010

European study indicates cardiovascular deaths can be avoided through better preventative care

Cardiovascular disease (CVD) is the leading cause of death in Europe, killing an estimated 4.3 million people each year. Results from a large pan-European study announced today indicate that many of these deaths could be avoided if at-risk patients received better preventative care.

9 Nov 2010

Study finds canola-type rapeseed oil decreases fibrinogen level

According to research on fatty acids conducted at the universities of Helsinki and Tampere, the consumption of canola-type rapeseed oil decreases the level of fibrinogen detrimental to health in the body. The increased fibrinogen level, caused by an imbalance in essential fats in one's diet, decreases when saturated fatty acids are replaced with rapeseed oil.

9 Nov 2010

Apples lower risk for developing heart disease

Recent research out of the University of Michigan Health System – a premier academic medical center – has found that adding more apples and apple products to your diet may be an easy way to lower your risk for developing heart disease. More than one in three U.S. adults has one or more types of cardiovascular disease (CVD) according to the American Heart Association. Heart disease is the leading cause of death in the United States.

8 Nov 2010

Cholesterol News and Research

Further Reading

Vit D deficiency does not raise stroke risk in African-Americans

Job strain can increase risk of cardiovascular disease in women

People with anxiety disorders require additional cardiac test: Study

ASN Annual Meeting to highlight six late-breaking clinical trials on nephrology

Think treatments for cancer, diabetes don't grow on trees? Think again

ESC emphasizes simple measures for diabetic patients to slow-down CVD progression

High cholesterol in midlife does not increase risk for Alzheimer's disease among women

Mother's poor nutrition during pregnancy affects offspring's ability to process medications

Study suggests mid-life cholesterol level may not linked to later development of Alzheimer's disease

Statins benefit ‘at risk’ patients but are underused: Study

Long-term use of statins unlikely to substantially increase overall cancer risk: Study

Researchers study drug's ability to restore retinal health in eyes of diabetic patients

Researchers to determine levels of stroke risk in patients with narrowed brain arteries

BioInvent receives FDA IND clearance for BI-204 Phase II trial in cardiovascular disease

Study demonstrates preventive effect of urate lowering therapy on cardiovascular mortality

Arena and Eisai report positive results from lorcaserin BLOOM-DM trial in obese, overweight diabetics

ORAL Solo Phase 3 study shows tasocitinib reduces signs and symptoms of active RA

European study indicates cardiovascular deaths can be avoided through better preventative care

Study finds canola-type rapeseed oil decreases fibrinogen level

Apples lower risk for developing heart disease

Sensing a Healthier Future

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Expanding research and clinical options for children with cancer

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