Cilia News and Research

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Can amodiaquine short circuit this pandemic?

A recent study by the US researchers highlights the value of the human organ chip technology as a more robust and physiologically relevant platform for rapid drug repurposing, and suggest that amodiaquine may be used to prevent the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Sep 2020

Ciliary proteins play vital role in cardiovascular functions and genetic diseases

Research from Chapman University provides new insight into the characteristics of crucial proteins within the ciliary membrane that play vital roles in human genetic diseases and cardiovascular functions.

20 Aug 2020

Gene variants help explain link between skin condition and food allergies

Two common variants in the KIF3A gene increase the risk of young children having a dysfunctional skin barrier and developing the skin condition atopic dermatitis.

14 Aug 2020

Research looks at convalescent plasma use in COVID-19 mouse model

A new study by researchers at the University of Iowa and published on the preprint server bioRxiv in August 2020 reports the utility of a mouse model that recapitulates several aspects of human COVID-19 and can reflect the antiviral efficacy of new drugs as well.

12 Aug 2020

Novel short ACE2 isoform may influence SARS-CoV-2 susceptibility

A study led by researchers at the University of Southampton, UK, has identified a novel short isoform of the full-length receptor that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses to gain entry to host cells.

3 Aug 2020

Mice born with Fragile X syndrome have fewer cell antennas

Structures called primary cilia - which act like TV antennas for cells to detect signals - are present in fewer numbers in mice born with Fragile X syndrome, according to researchers from The University of Texas Health Science Center at San Antonio.

30 Jul 2020

Scientists develop human lung organoids to study SARS-CoV-2 infection

Now, a new study published on the preprint server bioRxiv in July 2020 reports the development of a human distal lung culture system that can be functionally tested. This will help not only to understand how this infection produces disease but also to test the proliferative capacity of the stem cells in this part of the body.

30 Jul 2020

Sanford Burnham Prebys receives CIRM award to advance promising drug candidates for COVID-19

Sanford Burnham Prebys Medical Discovery Institute has received an award from the California Institute for Regenerative Medicine to advance promising drug candidates for COVID-19.

21 Jul 2020

Cell signaling pathway may offer new drugs for tuberous sclerosis complex

Tuberous sclerosis complex (TSC) is a neurological disorder causing non-cancerous tumors, called cortical tubers, to grow throughout the brain and body, as well as other conditions like epilepsy and autism.

24 Jun 2020

SARS-CoV-2 invasion of central nervous system through olfactory tract

As the COVID-19 pandemic continues to claim lives throughout the world, the evidence is mounting that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the respiratory tract as well as the central nervous system. Now, a new study by German researchers published on the preprint server bioRxiv in June 2020 describes various neurological manifestations of COVID-19, as well as the underlying pathophysiology.

7 Jun 2020

Fear of coronavirus propels some smokers to quit

In 40 years of smoking, Katie Kennedy has tried four times to quit but always went back to cigarettes. Today, she is summoning a new mental image when a craving comes on: rows of COVID-19 patients hooked to ventilators.

30 Apr 2020

Novel coronavirus targets specific secretory cells in the lungs

Viruses attack specific host cells, which can cause chaos in the body. The novel coronavirus, now called severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2 for short, infects respiratory epithelial cells in the lining of the lung, causing difficulty of breathing. The usual cause of death of those who contract the virus is pneumonia and acute respiratory distress syndrome (ARDS). Now, a new study has found that SARS-CoV-2 specifically attack certain progenitor cells called bronchial transient secretory cells in the lungs.

9 Apr 2020

What does COVID-19 do to the body?

The novel coronavirus SARS-CoV-2, also known as 2019-nCoV, is the virus that causes COVID-19, and that is spreading throughout the world is causing panic in almost all countries. With a death rate ranging from 1% to 2% in young patients but about 5%-8% in elderly and sick patients, it is capable of ravaging multiple organ systems in the human body.

12 Mar 2020

Scientists unravel mechanisms that lead to ventricular enlargement in schizophrenia

Enlarged cerebral ventricles are found in 80% of individuals with schizophrenia, yet the mechanisms that lead to ventricular enlargement are mostly unknown.

14 Feb 2020

New learning module for testing the effects of e-cigarette vapor on living cells

To complement the wide range of information on the potential dangers of vaping, the Cornell University College of Veterinary Medicine has developed a new learning module for high school classrooms that encourages students to directly test the effects of e-cigarette vapor on living cells.

12 Jan 2020

Cilia News and Research

Can amodiaquine short circuit this pandemic?

Ciliary proteins play vital role in cardiovascular functions and genetic diseases

Gene variants help explain link between skin condition and food allergies

Research looks at convalescent plasma use in COVID-19 mouse model

Novel short ACE2 isoform may influence SARS-CoV-2 susceptibility

Mice born with Fragile X syndrome have fewer cell antennas

Scientists develop human lung organoids to study SARS-CoV-2 infection

Sanford Burnham Prebys receives CIRM award to advance promising drug candidates for COVID-19

Cell signaling pathway may offer new drugs for tuberous sclerosis complex

SARS-CoV-2 invasion of central nervous system through olfactory tract

Fear of coronavirus propels some smokers to quit

Novel coronavirus targets specific secretory cells in the lungs

What does COVID-19 do to the body?

Scientists unravel mechanisms that lead to ventricular enlargement in schizophrenia

New learning module for testing the effects of e-cigarette vapor on living cells

Study provides better understanding of mechanisms that limit cilia number in cells

Research finds key reason why brain connectivity goes awry in rare neurodevelopmental conditions

Research shows how cilia and exocyst contribute to extracellular vesicle production

New imaging methods provide unprecedented close-up view of cilia linked to blindness

Vaping destroys lining and immune cells in the lung, says study

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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