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Breakthrough in gene editing: Enhanced virus-like particles promise new era in genetic disease treatment

Researchers developed an advanced prime editor-engineered virus-like particle (PE-eVLP) system, significantly enhancing gene editing efficiency in human cells and showing potential for treating genetic diseases.

9 Jan 2024

Study opens doors for more effective OCD treatment based on individual brain profiles

Marking a substantial advancement in understanding OCD, researchers from Zhejiang University School of Medicine have revealed key connections between clinical characteristics, neuroimaging and treatment, heralding new opportunities for improved diagnostic and therapeutic strategies.

9 Jan 2024

Photobiomodulation alleviates Aβ deposition and cognitive decline in mice with Alzheimer’s disease

Alzheimer's disease (AD) is an age-related neurodegenerative disorder. β-amyloid (Aβ) deposition in the brain is a crucial contributor to the pathogenesis of AD, mitigating excessive cerebral Aβ burden has been considered as a possible therapeutic strategy for AD.

8 Jan 2024

Engineered virus-like particles power up gene editing, correcting blindness in mice

Prime editing, a versatile form of gene editing that can correct most known disease-causing genetic mutations, now has a new vehicle to deliver its machinery into cells in living animals.

8 Jan 2024

Does being physically fit improve your attention span?

Better physical fitness is associated with better attention and concentration.

8 Jan 2024

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Folate is a B vitamin and a necessary nutrient to prevent neural tube defects, such as spina bifida. Folic acid, a synthetic form of folate, has been added to vitamins, breakfast cereals and other products in the U.S. and more than 80 other countries to ensure pregnant women get adequate amounts.

4 Jan 2024

Stanford Medicine researchers demonstrate new way to temporarily heighten hypnotizablity

How deeply someone can be hypnotized -; known as hypnotizability -; appears to be a stable trait that changes little throughout adulthood, much like personality and IQ.

4 Jan 2024

Retinotopic coding bridges perception and memory in the brain, study finds

Study reveals that retinotopic coding in the brain cortex plays a crucial role in processing visual information from the retina, influencing both perception and memory systems.

3 Jan 2024

Mount Sinai study provides a mechanistic explanation for variations in individual responses to drugs

Mount Sinai researchers have shown for the first time that a person's beliefs related to drugs can influence their own brain activity and behavioral responses in a way comparable to the dose-dependent effects of pharmacology.

3 Jan 2024

Gut microbiota linked to social anxiety behaviors

Study reveals that gut microbiota from individuals with social anxiety disorder (SAD) can induce social fear behaviors in mice, suggesting a causal role of gut microbes in modulating behaviors relevant to SAD.

2 Jan 2024

Healthy aging modulates the neural oscillatory dynamics serving working memory function

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 24, entitled, "Age-related alterations in the oscillatory dynamics serving verbal working memory processing."

2 Jan 2024

Study reveals novel neural coding mechanism for transferring perceptual information to memory

Our memories are rich in detail: we can vividly recall the color of our home, the layout of our kitchen, or the front of our favorite café. How the brain encodes this information has long puzzled neuroscientists.

2 Jan 2024

Increased β-amyloid accumulation may be linked to Alzheimer’s dementia risk in oldest of the old

A new study indicates that severity of amyloid deposition in the brain -; not just age -; may be key to determining who will benefit from new anti-amyloid therapies to delay the progression of Alzheimer's disease.

26 Dec 2023

New research debunks color's influence on the human internal clock

Vision is a complex process. The visual perception of the environment is created by a combination of different wavelengths of light, which are decoded as colors and brightness in the brain.

22 Dec 2023

Study reveals how measles virus mutates and spreads in the human brain

Mayo Clinic researchers mapped how the measles virus mutated and spread in the brain of a person who succumbed to a rare, lethal brain disease.

21 Dec 2023

Sniffing women’s tears could be the key to taming male aggression

New research, publishing December 21st in the open access journal in PLOS Biology, shows that tears from women contain chemicals that block aggression in men.

21 Dec 2023

New research investigates the impact of binaural beat on language skills

New research conducted by the Center for BrainHealth at The University of Texas at Dallas investigates the impact of binaural beat (BB) on language skills. BB is a sound that occurs when two slightly mismatched pure tones are heard.

21 Dec 2023

Study reveals brain's built-in mechanism for stitching experiences into memories

Scientists at NTNU's Kavli Institute for Systems Neuroscience in Norway have discovered a pattern of activity in the brain that serves as a template for building sequential experiences.

20 Dec 2023

UW-Madison technology unveils autism gene's impact on early brain structure

Technology developed at the University of Wisconsin–Madison to grow "rosettes" of brain and spinal tissue gives scientists new ways to study the growing human brain, including a recent study of how genetic mutations linked to autism affect early stages of human brain development.

20 Dec 2023

Study reveals extensive postnatal neuronal migration in human entorhinal cortex

The human brain continues to be built after we are born for far longer than previously recognized, suggests research by Shawn Sorrells, assistant professor of neuroscience in the Kenneth P. Dietrich School of Arts and Sciences.

20 Dec 2023

Cortex News and Research

Breakthrough in gene editing: Enhanced virus-like particles promise new era in genetic disease treatment

Study opens doors for more effective OCD treatment based on individual brain profiles

Photobiomodulation alleviates Aβ deposition and cognitive decline in mice with Alzheimer’s disease

Engineered virus-like particles power up gene editing, correcting blindness in mice

Does being physically fit improve your attention span?

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Stanford Medicine researchers demonstrate new way to temporarily heighten hypnotizablity

Retinotopic coding bridges perception and memory in the brain, study finds

Mount Sinai study provides a mechanistic explanation for variations in individual responses to drugs

Gut microbiota linked to social anxiety behaviors

Healthy aging modulates the neural oscillatory dynamics serving working memory function

Study reveals novel neural coding mechanism for transferring perceptual information to memory

Increased β-amyloid accumulation may be linked to Alzheimer’s dementia risk in oldest of the old

New research debunks color's influence on the human internal clock

Study reveals how measles virus mutates and spreads in the human brain

Sniffing women’s tears could be the key to taming male aggression

New research investigates the impact of binaural beat on language skills

Study reveals brain's built-in mechanism for stitching experiences into memories

UW-Madison technology unveils autism gene's impact on early brain structure

Study reveals extensive postnatal neuronal migration in human entorhinal cortex

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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