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Cortisol is a hormone made by the adrenal cortex (the outer layer of the adrenal gland). It helps the body use glucose (a sugar), protein, and fats. Cortisol made in the laboratory is called hydrocortisone. It is used to treat many conditions, including inflammation, allergies, and some cancers. Cortisol is a type of glucocorticoid hormone.
Female rats whose great grandparents exposed to toxins become more vulnerable to stress

Female rats whose great grandparents exposed to toxins become more vulnerable to stress

Scientists have known that toxic effects of substances known as endocrine disrupting chemicals (EDCs), found in both natural and human-made materials, can pass from one generation to the next, but new research shows that females with ancestral exposure to EDC may show especially adverse reactions to stress. [More]
Amygdala stimulates stress responses in adults, say researchers

Amygdala stimulates stress responses in adults, say researchers

In contrast to evidence that the amygdala stimulates stress responses in adults, researchers at Yerkes National Primate Research Center, Emory University have found that the amygdala has an inhibitory effect on stress hormones during the early development of nonhuman primates. [More]
Study links high cortisol in infants with socioeconomic status of mothers during pregnancy

Study links high cortisol in infants with socioeconomic status of mothers during pregnancy

Women who are poor experience higher cortisol levels in pregnancy and give birth to infants with elevated levels of the stress hormone, putting them at greater risk for serious disease later in life, according to a new research from the University of Colorado Denver. [More]
Fluticasone furoate effective in moderate-to-severe asthma

Fluticasone furoate effective in moderate-to-severe asthma

Once daily fluticasone furoate, used at a dose of 100 µg or 200 µg, provides substantial improvements in lung function and asthma control for patients with uncontrolled moderate-to-severe asthma, phase III trial results show. [More]
Alterations to single gene could predict risk of suicide attempt

Alterations to single gene could predict risk of suicide attempt

Johns Hopkins researchers say they have discovered a chemical alteration in a single human gene linked to stress reactions that, if confirmed in larger studies, could give doctors a simple blood test to reliably predict a person's risk of attempting suicide. [More]
Peer-led interventions can reduce depression and anxiety in mothers of kids with autism

Peer-led interventions can reduce depression and anxiety in mothers of kids with autism

Peer-led interventions that target parental well-being can significantly reduce stress, depression and anxiety in mothers of children with disabilities, according to new findings released today in the journal Pediatrics. [More]
Women experiencing stressful events the day before eating high-fat meal can slow body's metabolism

Women experiencing stressful events the day before eating high-fat meal can slow body's metabolism

A new study in women suggests that experiencing one or more stressful events the day before eating a single high-fat meal can slow the body's metabolism, potentially contributing to weight gain. [More]
Novel device uses smartphone to measure cortisol concentration in saliva

Novel device uses smartphone to measure cortisol concentration in saliva

Researchers have developed a device that uses any smartphone to measure the cortisol concentration in saliva. The device was presented Tuesday, June 24, at ICE/ENDO 2014, the joint meeting of the International Society of Endocrinology and the Endocrine Society in Chicago. [More]
Patients with Cushing’s syndrome experience significant weight loss while taking oral medication

Patients with Cushing’s syndrome experience significant weight loss while taking oral medication

Sinai Hospital of Baltimore endocrinologist, Henry G. Fein, M.D., today presented new research showing that patients with Cushing's syndrome, a rare disease that can lead to extreme weight gain, type 2 diabetes, high blood pressure and psychological issues, experienced significant, sustained weight loss while taking oral medication daily over a number of years to manage symptoms of the disease. [More]
Depression 5 times common in people with bipolar disorder who have low levels of cortisol

Depression 5 times common in people with bipolar disorder who have low levels of cortisol

Depression is almost twice as common, and poor quality of life almost five times as common, in people with bipolar disorder who have elevated or low levels of the stress hormone cortisol in the blood. [More]
Stress may accelerate cognitive decline later in life

Stress may accelerate cognitive decline later in life

A new study published in the June 18 issue of The Journal of Neuroscience adds to a body of evidence suggesting stress may accelerate cognitive decline later in life. [More]
Unborn children exposed to severe stress levels have increased risk of becoming overweight

Unborn children exposed to severe stress levels have increased risk of becoming overweight

There are indications that unborn children who are exposed to severe stress levels, have an increased risk of becoming overweight or developing obesity as adults. [More]
Exposure to elevated levels of steroid hormones in the womb linked to later development of autism

Exposure to elevated levels of steroid hormones in the womb linked to later development of autism

Scientists from the University of Cambridge and the Statens Serum Institute in Copenhagen, Denmark have discovered that children who later develop autism are exposed to elevated levels of steroid hormones (for example testosterone, progesterone and cortisol) in the womb. The finding may help explain why autism is more common in males than females, but should not be used to screen for the condition. [More]
Young adult social drinkers may develop alcohol use disorder over time

Young adult social drinkers may develop alcohol use disorder over time

Heavy social drinkers who report greater stimulation and reward from alcohol are more likely to develop alcohol use disorder over time, report researchers from the University of Chicago, May 15 in the journal Biological Psychiatry. [More]
Novartis presents Phase III results of Signifor LAR therapy in patients with acromegaly

Novartis presents Phase III results of Signifor LAR therapy in patients with acromegaly

Novartis today presented results from a pivotal Phase III trial of investigational therapy Signifor® LAR (pasireotide LAR; SOM230) in patients with acromegaly for whom current standard of care provides inadequate disease control. [More]
Girls labeled fat at age 10 are more likely to be obese at 19, say researchers

Girls labeled fat at age 10 are more likely to be obese at 19, say researchers

Girls who are told by a parent, sibling, friend, classmate or teacher that they are too fat at age 10 are more likely to be obese at age 19, a new study by UCLA psychologists shows. [More]
Youth who work with horses experience substantial reduction in stress

Youth who work with horses experience substantial reduction in stress

New research from Washington State University reveals how youth who work with horses experience a substantial reduction in stress - and the evidence lies in kids' saliva. [More]
DNA modifications in blood are directly related to changes in brain tissues, say researchers

DNA modifications in blood are directly related to changes in brain tissues, say researchers

Johns Hopkins researchers say they have confirmed suspicions that DNA modifications found in the blood of mice exposed to high levels of stress hormone — and showing signs of anxiety — are directly related to changes found in their brain tissues. [More]
Researchers discover hotspot L205R mutation is closely associated with adrenocortical tumors

Researchers discover hotspot L205R mutation is closely associated with adrenocortical tumors

Chinese researchers from Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, BGI, and other institutions have discovered that the activating hotspot L205R mutation in PRKACA gene was closely associated with adrenocortical tumors (ACTs), and the relationship of recurrently mutated DOT1L and CLASP2 with ACTs' other subtypes. [More]
Study highlights importance of stress management, healthy lifestyle habits for people with migraine

Study highlights importance of stress management, healthy lifestyle habits for people with migraine

Migraine sufferers who experienced reduced stress from one day to the next are at significantly increased risk of migraine onset on the subsequent day, according to a new study conducted by researchers at the Montefiore Headache Center and Albert Einstein College of Medicine at Yeshiva University. [More]