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New method to estimate bleeding risk in heart attack patients

With eight basic medical facts in hand, doctors can now estimate the risk of bleeding for a patient having a heart attack.

14 Apr 2009

New model helps predict risk of new onset heart failure in the elderly

Researchers at Emory University School of Medicine created the Health ABC Heart Failure Model for predicting risk of new onset heart failure in the elderly.

30 Mar 2009

Dapagliflozin trial results indicate improvement in key glycemic measures in treatment-naive type 2 diabetes

Findings published in Diabetes Care from a 12-week, Phase IIb dose-ranging study showed that dapagliflozin, a novel, selective, sodium glucose co-transporter2 (SGLT2) inhibitor, produced clinically meaningful reductions across all key glycemic measures studied [glycosylated hemoglobin level (HbA1c), fasting plasma glucose (FPG), and postprandial plasma glucose (PPG)] in treatment-naive type 2 diabetes patients, compared to placebo.

29 Mar 2009

FDA approves Symbyax for treatment-resistant depression

The U.S. Food and Drug Administration (FDA) has approved a new indication for Symbyax (olanzapine and fluoxetine HCl capsules), Eli Lilly and Company has announced.

23 Mar 2009

Updated formula measures kidney function more accurately

Measuring kidney function in children can be expensive, time-consuming for clinicians, and tedious for children, who may be exposed to radioactivity and subjected to a large number of blood draws.

24 Feb 2009

Updated formula measures kidney function more accurately

Measuring kidney function in children can be expensive, time-consuming for clinicians, and tedious for children, who may be exposed to radioactivity and subjected to a large number of blood draws.

24 Feb 2009

New method for projecting future kidney function in transplants

The older the kidney, the worse it works - though exactly how much worse isn't known.

27 Jan 2009

Three new nomograms predict successful kidney transplant outcomes

Kidney transplants are the best available therapy for end stage renal disease.

23 Jan 2009

New formula accurately measures kidney function in children

Measuring a child's kidney function has traditionally been time-consuming, costly, and difficult to perform, but a new equation that uses parameters collected at routine office visits can effectively accomplish this, according to a study appearing in the March 2009 issue of the Journal of the American Society Nephrology ( JASN ).

21 Jan 2009

Measurement of kidney function in children with kidney disease improved

A formula used to measure kidney function in children with chronic kidney disease has been revised to make it more precise, according to a study published today in the Journal of the American Society of Nephrology.

21 Jan 2009

Lilly receives complete response letter for Olanzapine LAI for treatment of schizophrenia

Eli Lilly and Company has announced that it received a complete response letter from the U.S. Food and Drug Administration (FDA) for olanzapine long-acting injection (LAI) for acute and maintenance treatment of schizophrenia in adults.

7 Jan 2009

Zometa (zoledronic acid) shown to enhance chemotherapy in reducing breast tumor size

New data released demonstrates that the addition of Zometa (zoledronic acid) injection to standard chemotherapy before breast cancer surgery reduces the size of breast tumors more effectively than chemotherapy alone in women with early-stage disease.

14 Dec 2008

Improvement seen regarding racial disparities for liver transplantation, disparities for women remain

Following introduction of a new system in 2002 to determine the allocation of donated livers, black patients no longer are less likely to receive a liver transplant, but disparities for women remain, according to a study in the November 26 issue of JAMA, the Journal of the American Medical Association.

25 Nov 2008

New equation provides more accurate estimates of the glomerular filtration rate

A newly developed equation produces more accurate estimates of the glomerular filtration rate (GFR) - a key indicator of kidney function in patients with chronic kidney disease (CKD), according to research being presented at the American Society of Nephrology's 41st Annual Meeting and Scientific Exposition in Philadelphia, Pennsylvania.

8 Nov 2008

Further analysis from ATHENA study showed Multaq (Dronedarone) reduced risk of stroke in patients with atrial fibrillation

The results of a post-hoc analysis of the data from the ATHENA study were presented today at the clinical trial update session of the European Society of Cardiology congress 2008, in Munich, Germany.

3 Sep 2008

Gleevec receives FDA priority review for gastrointestinal stromal tumors after surgery

Novartis has announced that Gleevec (imatinib mesylate) tablets, (known as Glivec (imatinib) outside the US, Canada and Israel), has been granted priority review status by the US Food and Drug Administration (FDA) as the first therapy to be reviewed for use after surgery in kit-positive gastrointestinal stromal tumors (GIST).

27 Aug 2008

Collaborative effort by FDA and EMEA expected to yield additional safety data when assessing new drugs

In the first use of a framework allowing submission of a single application to the two agencies, the Food and Drug Administration (FDA) and the European Medicines Agency (EMEA) worked together to allow drug companies to submit the results of seven new tests that evaluate kidney damage during animal studies of new drugs. The tests measure the levels of seven key proteins or "biomarkers" found in urine that can provide additional information about drug-induced damage to kidney cells, also known as renal toxicity.

15 Jun 2008

NGAL protein levels in simple urine test speed diagnosis of failing kidneys

Walk into any emergency department complaining of chest pain and you are likely to have blood drawn. Within hours it should be clear whether you've had a heart attack, based on enzyme levels in your blood and whether those levels reveal the tissue damage normally associated with a heart attack or other major cardiac event.

2 Jun 2008

FDA approves Actonel (risedronate sodium) for postmenopausal osteoporosis

The U.S. Food and Drug Administration (FDA) approved a new once-a-month dose (150 mg) of Actonel (risedronate sodium) tablets for the treatment and prevention of postmenopausal osteoporosis. Actonel is approved to reduce the risk of fractures in postmenopausal women with osteoporosis.

24 Apr 2008

Tredaptive and Janumet recommended for approval in European Union

Food and Drug Administration (FDA) is currently reviewing the combination of extended release (ER) niacin and laropiprant under the trademark Cordaptive (ER niacin/laropiprant). The CHMP recommendation does not apply to regulatory decisions by the FDA and no inferences should be made about pending FDA regulatory actions based on the recommendation of the CHMP.

24 Apr 2008