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Early wheezers continue to have poorer lung function as they age

Among children who exhibit asthma-like symptoms during preschool years, researchers have found that patterns of wheezing prevalence and levels of lung function are established by age 6 and do not significantly change for at least 10 years.

21 Nov 2005

University of Alberta researchers pioneer gene therapy to restore alveoli and lung capillaries in damaged rat lungs

The good news is that medical advances in perinatal care have allowed us to save many more premature babies. The bad news is they're often at risk of developing bronchopulmonary dysplasia--a chronic lung disease caused by having to place the tiny infants on ventilators and oxygen-rich therapy for acute respiratory failure.

13 Nov 2005

Strong association between physical and mental health problems and restless legs syndrome

Adults with restless legs syndrome (RLS), a common debilitating condition, may be affected physically, mentally, and socially by their disease.

1 Nov 2005

Controlling antibiotic-prescribing practices in hospitals

Plenty of promising strategies exist to control antibiotic-prescribing practices, but no single method emerges as the best for hospital patients, according to a new review of studies.

18 Oct 2005

Researchers find CCL5 protein produced in the course of respiratory viral infections can serve to protect macrophages from an untimely death

Enlisted to help fight viral infections, immune cells called macrophages consume virus-infected cells to stop the spread of the disease in the body.

9 Oct 2005

Patients in level I trauma centers were nearly 20 percent less likely to die than those in level II centers

Patients who are taken to a level 2 trauma center after suffering serious injury are significantly more likely to die than comparable patients treated at a major level 1 trauma center, according to researchers at the Keck School of Medicine of the University of Southern California.

9 Oct 2005

Greasing the gears that drive the interferon signal

Interferon -- a critical protein that mediates the body's defense against a wide variety of infectious agents and tumors -- may soon have greater therapeutic value as the result of a new study by researchers at Washington University School of Medicine in St. Louis.

3 Oct 2005

Music helps people with chronic obstructive pulmonary disease focus on their breathing

Before the music can begin, the harmonica teacher makes sure everyone is in position. "Sit up straight. Feet on the floor. Try to breathe from the belly," she says.

28 Sep 2005

Fndings could lead to a treatment for idiopathic interstitial pneumonia

An incurable, deadly lung disorder, "idiopathic interstitial pneumonia" (IIP), whose causes were mysterious arises from a combination of a genetic predisposition and damage due to inhaled chemicals, notably from cigarette smoking, Duke University Medical Center researchers have found.

27 Sep 2005

Family-centered approach improves communication and care in intensive care unit

A nationwide hospital program developed to support families visiting loved ones in the intensive care unit (ICU) has significant benefits for families, patients, and team members in the ICU, shows a new study.

20 Sep 2005

More than two thirds of meta-analyses available to critical care physicians have major methodological flaws

Research published in Critical Care concludes that the overall quality of meta-analyses in this field is poor, but has improved over time, possibly due to the publication of the Quality of Reporting of Meta-analyses statement (QUOROM) in 1999.

19 Sep 2005

Bacteria lurking in household dust produce chemicals that may trigger asthma

These bacterial chemicals, called endotoxins, particularly those found on bedroom floors, were linked with increased respiratory problems in adults.

7 Sep 2005

More than 15 percent of our genes are mobilized to defend against microbial attacks

The body's overwhelming genetic defense, which has implications for the survival of patients who are severely burned or injured, was revealed in a sweeping analysis of gene activity in volunteers who were injected with a bacterial product that temporarily created flu-like symptoms.

1 Sep 2005

When it comes to inflammation, too much of a good thing can be deadly

In some severely injured patients, this normal healing process can develop into a lethal, whole-body response, including bloodstream infection (sepsis) and multiple organ failure. How and why inflammation turns from healing to harming is still mysterious, so doctors can't accurately predict how each injured patient will fare.

31 Aug 2005

Inexpensive method to assess the stability and quality of sleep

Using information hidden in the beat-to-beat changes of the heart's electrical signals, researchers at Beth Israel Deaconess Medical Center (BIDMC) have developed an inexpensive method to assess the stability and quality of sleep, which could be used to help understand the mechanisms of sleep control and diagnose sleep disorders, as well as to test the efficacy of sleep aids and other medications.

29 Aug 2005

Communication from physicians and health care teams needs to improve to meet patient's needs

Researchers report in the current issue of Mayo Clinic Proceedings that more than one-half of their study patients were unable to list their medications, diagnoses, treatment plan (names and purposes of medications) and common side effects of prescribed medications.

2 Aug 2005

Moraxella catarrhalis found to be responsible for 10 percent of exacerbations of COPD

A ubiquitous bacterial strain thought to be uninvolved in chronic obstructive pulmonary disease (COPD) in fact is responsible for 2-4 million flare-ups of the condition that occur annually in the United States, researchers from the University at Buffalo have shown.

20 Jul 2005

Many paramedics do not get enough clinical experience in insertion of emergency breathing tubes

Across the United States, many patients require insertion of emergency breathing tubes before arriving to a hospital, but emergency medicine researchers at the University of Pittsburgh School of Medicine have found that many paramedics - the highest level of prehospital providers - do not get enough clinical experience in this life-saving skill.

19 Jul 2005

PGE2 may be a target for Celebrex therapy

A product produced by lung cancer tumors fuels the cells that suppress immune function in patients and may be a target for Celebrex therapy, giving oncologists another weapon to fight cancer, according to a study by researchers at UCLA's Jonsson Cancer Center.

17 Jul 2005

Australian doctors must be involved in planning medical response to possible local terror attacks

Australian Medical Association (AMA) President, Dr Mukesh Haikerwal, said this week it is vitally important that the AMA takes a key coordinating role in planning the medical response to any disasters including terror attacks on Australian soil.

14 Jul 2005