Crystallography News and Research

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Griffith University uncovers first 3-D image of protein linked to cancer spread

Griffith University's Institute for Glycomics has made scientific history by determining the first three-dimensional image of a protein linked to the spread of cancer.

3 Nov 2015

Study suggests potential new way to block cancer-causing gene

A new study suggests a potential new way to block one of the most common cancer-causing genes, without causing severe side effects.

28 Oct 2015

Research shows deep-sea bacteria could help neutralize atmospheric greenhouse gases

A type of bacteria plucked from the bottom of the ocean could be put to work neutralizing large amounts of industrial carbon dioxide in the Earth's atmosphere, a group of University of Florida researchers has found.

23 Oct 2015

Ground-breaking discovery helps scientists view DNA damage with crystal clarity

Scientists have developed a new technique for looking at the initial steps of DNA oxidation – a process which can lead to DNA damage, mutations and cancers. The breakthrough, which uses DNA in crystals, should help related research in the fields of cancer medicine and drug development.

22 Oct 2015

OSU discovery sheds new light on how proteins fold

Biochemists at Oregon State University have made a fundamental discovery about protein structure that sheds new light on how proteins fold, which is one of the most basic processes of life.

19 Oct 2015

Hiroshima University researchers demonstrate how Sendai virus escapes host immune system

A research group at Hiroshima University demonstrated the mechanism by which the Sendai virus (SeV) escapes the host immune system. The researchers examined the crystal structure of the complex of SeV C protein and transcription factor STAT1, and found that SeV C protein inhibits the signal transduction pathway of interferon gamma.

16 Oct 2015

Researchers create high resolution images of telomerase that plays major role in cancer, aging

An enzyme called telomerase plays a significant role in aging and most cancers, but until recently many aspects of the enzyme's structure could not be clearly seen.

16 Oct 2015

New COMPASS platform points directly to protein's likely structure

Searching for the precise, complexly folded three-dimensional structure of a protein can be like hacking through a jungle without a map: a long, intensive process with uncertain direction.

16 Oct 2015

Researchers unlock structural details of key protein to treat neuromuscular disease

Researchers at Rice University and Baylor College of Medicine have unlocked the structural details of a protein seen as key to treating a neuromuscular disease.

30 Sep 2015

UC San Diego, TSRI form new consortium to map cells in space and time

Drawing on complementary strengths of two San Diego institutions, The Scripps Research Institute (TSRI) and the University of California, San Diego (UC San Diego) have formed a new consortium with a big mission: to map cells in space and time.

18 Sep 2015

Caltech researchers find antibody that can detect, neutralize HIV viruses in infected patients

Proteins called broadly neutralizing antibodies (bNAbs) are a promising key to the prevention of infection by HIV, the virus that causes AIDS. bNAbs have been found in blood samples from some HIV patients whose immune systems can naturally control the infection.

14 Sep 2015

SLU scientist receives grant to solve blood-clotting mysteries

Last summer, SLU scientists made a breakthrough discovery about the way in which blood clots. Through X-ray crystallography, they solved the molecular structure of prothrombin, an important blood-clotting protein, revealing an unexpected, flexible role for a "linker" region that may be the key to developing better life-saving drugs.

1 Sep 2015

Scientists reveal role of dynamin and show how specific mutations impair function of dynamin

Cells continually form membrane vesicles that are released into the cell. If this vital process is disturbed, nerve cells, for example, cannot communicate with each other. The protein molecule dynamin is essential for the regulated formation and release of many vesicles.

28 Aug 2015

Long lasting flu vaccine using antibodies advance from TSRI and Janssen

Scientists from The Scripps Research Institute (TSRI) and the Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen) have found a way to induce antibodies to fight a wide range of influenza subtypes—work that could one day eliminate the need for repeated seasonal flu shots.

26 Aug 2015

Better drug design may soon be aided by Scripps scientists’ discoveries

For the first time, they have uncovered the structural details of how some proteins interact to turn two different signals into a single integrated output. These new findings could aid future drug design by giving scientists an edge in fine tuning the signal between these partnered proteins—and the drug’s course of action.

25 Aug 2015

New TSRI study may have important implications for better drug design

Scientists from The Scripps Research Institute Florida campus have uncovered the structural details of how some proteins interact to turn two different signals into a single integrated output. These new findings could aid future drug design by giving scientists an edge in fine tuning the signal between these partnered proteins—and the drug's course of action.

25 Aug 2015

TSRI, Janssen collaborate to find universal flu vaccine

Scientists from The Scripps Research Institute and the Janssen Pharmaceutical Companies of Johnson & Johnson have found a way to induce antibodies to fight a wide range of influenza subtypes—work that could one day eliminate the need for repeated seasonal flu shots.

24 Aug 2015

New ASU-POSTECH collaboration aims to discover biological molecules for health care, renewable energy research

The Biodesign Institute at Arizona State University and Pohang University of Science and Technology (POSTECH), Pohang, South Korea, have announced a partnership that will catalyze discoveries with a major impact on health care and clean energy applications.

24 Aug 2015

Researchers establish structure of important tumor-suppressing protein

An international group of researchers led by Carnegie Mellon University physicists Mathias Lösche and Frank Heinrich have established the structure of an important tumor suppressing protein, PTEN. Their findings provide new insights into how the protein regulates cell growth and how mutations in the gene that encodes the protein can lead to cancer.

21 Aug 2015

Tiny nanocrystals could be used in advanced medical imaging technologies to light up cancer cells

Researchers in China have developed tiny nanocrystals that could be used in the next generation of medical imaging technologies to light up cancer cells.

20 Aug 2015

Crystallography News and Research

Griffith University uncovers first 3-D image of protein linked to cancer spread

Study suggests potential new way to block cancer-causing gene

Research shows deep-sea bacteria could help neutralize atmospheric greenhouse gases

Ground-breaking discovery helps scientists view DNA damage with crystal clarity

OSU discovery sheds new light on how proteins fold

Hiroshima University researchers demonstrate how Sendai virus escapes host immune system

Researchers create high resolution images of telomerase that plays major role in cancer, aging

New COMPASS platform points directly to protein's likely structure

Researchers unlock structural details of key protein to treat neuromuscular disease

UC San Diego, TSRI form new consortium to map cells in space and time

Caltech researchers find antibody that can detect, neutralize HIV viruses in infected patients

SLU scientist receives grant to solve blood-clotting mysteries

Scientists reveal role of dynamin and show how specific mutations impair function of dynamin

Long lasting flu vaccine using antibodies advance from TSRI and Janssen

Better drug design may soon be aided by Scripps scientists’ discoveries

New TSRI study may have important implications for better drug design

TSRI, Janssen collaborate to find universal flu vaccine

New ASU-POSTECH collaboration aims to discover biological molecules for health care, renewable energy research

Researchers establish structure of important tumor-suppressing protein

Tiny nanocrystals could be used in advanced medical imaging technologies to light up cancer cells

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Expanding research and clinical options for children with cancer

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