Cytokine News and Research

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Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants

Five DNA vaccine candidates based on different SARS-CoV-2 strains.

12 Dec 2023

New optimized vaccine approach targets Hepatitis C virus variability

A method to design vaccines for highly variable viruses like the hepatitis C virus.

12 Dec 2023

Double punch for B-cell lymphomas: CAR T-cell innovation boosts efficacy, cuts toxicity

The Malaghan Institute of Medical Research in collaboration with Wellington Zhaotai Therapies Limited today announced results of its phase 1 dose escalation trial of a new third-generation anti-CD19 chimeric antigen receptor (CAR) T-cell therapy to be presented at the American Society of Hematology (ASH) Annual Meeting in San Diego on 11 December, 3pm.

11 Dec 2023

CAR-T cell therapy remains viable for patients in lymphoma remission, study finds

A study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests that CAR-T immunotherapy remains a viable option for patients who have lymphoma that goes into remission before the cell therapy begins.

11 Dec 2023

Phase I clinical trial of new CAR T cell therapy AT101 shows promising early responses

Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose levels studied in the trial, according to researchers from the University of Pennsylvania Perelman School of Medicine and Penn Medicine's Abramson Cancer Center.

11 Dec 2023

Study explores the intricate gut-brain-liver connection and its impact on health

Study reviews the gut-brain-liver axis, revealing the complex interplay between these organs in health and disease and the implications for therapeutic interventions, focusing on how gut microbiota affects liver and brain health.

10 Dec 2023

Repeated mRNA vaccines supercharge immune response against COVID-19, study finds

Study published in Nature Immunology reveals that repeated mRNA COVID-19 vaccinations enhance immune response, especially in previously infected individuals, leading to a diversified and increased number of immune cell clones and a stronger ability to combat various virus strains.

7 Dec 2023

Liver trigger holds the key to boosting gene therapy success

Indiana University School of Medicine researchers have uncovered vital insights regarding a liver trigger that blocks an undesired immune response from gene therapy, surprisingly resulting in the activation of specific immune cells, despite the liver's typical role in suppressing immune responses.

7 Dec 2023

Birth control pills may alter stress response, increase inflammation risk, study suggests

A new UCLA Health study is shedding light on how using hormonal contraceptive pills may affect women's responses to stress and their risk for inflammation-related illnesses.

7 Dec 2023

Sympathetic nervous system and immune interplay: Key to metabolic regulation

A review in Advanced Science explores the interaction between the immune system and the sympathetic nervous system in regulating vital metabolic organs like the pancreas, liver, and adipose tissues. This comprehensive analysis provides insights into the neuroimmune relationships affecting metabolism, offering potential new therapeutic strategies for metabolic diseases.

5 Dec 2023

New biomarker for inflammatory bowel disease identified through reverse metabolomics

In recent years, microbiome research has started to shift its focus from the microbes themselves to the molecules they produce.

5 Dec 2023

Carrot juice boosts immune response, cuts inflammation, new study reveals

A study in the journal Nutrients by Danish researchers shows that consuming carrot juice, rich in falcarinol and falcarindiol, influences acute inflammatory mediators and innate immune responses in human blood.

4 Dec 2023

Controlling high blood pressure may not be enough to prevent related cognitive declines, study finds

Researchers at Weill Cornell Medicine have found that controlling high blood pressure may not be enough to prevent associated cognitive declines.

4 Dec 2023

Postpartum phagocytosis of pancreatic β-cells by macrophages regulates blood glucose levels

Pancreatic beta cells (β-cells) reside in a cluster of cells in the pancreas known as the islets of Langerhans.

4 Dec 2023

Study links placental Group B Streptococcus to higher neonatal unit admissions in newborns

The clinical significance of Streptococcus agalactiae (Group B Streptococcus; GBS) deoxyribonucleic acid (DNA) in the placenta.

4 Dec 2023

Gut microbe Lactobacillus found to bolster stress resilience, new study reveals

Study demonstrates that the gut microbe Lactobacillus helps maintain normal levels of the cytokine interferon-gamma (IFNγ), providing protection against stress-induced disruptions in a mouse model. The findings suggest Lactobacillus's crucial role in building resilience to environmental stressors, highlighting its potential in treating mood disorders.

3 Dec 2023

Cytokine News and Research

Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants

New optimized vaccine approach targets Hepatitis C virus variability

Double punch for B-cell lymphomas: CAR T-cell innovation boosts efficacy, cuts toxicity

CAR-T cell therapy remains viable for patients in lymphoma remission, study finds

Phase I clinical trial of new CAR T cell therapy AT101 shows promising early responses

Study explores the intricate gut-brain-liver connection and its impact on health

Repeated mRNA vaccines supercharge immune response against COVID-19, study finds

Liver trigger holds the key to boosting gene therapy success

Birth control pills may alter stress response, increase inflammation risk, study suggests

Sympathetic nervous system and immune interplay: Key to metabolic regulation

New biomarker for inflammatory bowel disease identified through reverse metabolomics

Carrot juice boosts immune response, cuts inflammation, new study reveals

Controlling high blood pressure may not be enough to prevent related cognitive declines, study finds

Postpartum phagocytosis of pancreatic β-cells by macrophages regulates blood glucose levels

Study links placental Group B Streptococcus to higher neonatal unit admissions in newborns

Gut microbe Lactobacillus found to bolster stress resilience, new study reveals

New approach enhances CAR T-cell therapy for solid tumors

Revolutionary advances in psoriasis treatment: unveiling new therapeutic approaches

Potential breakthrough in breast cancer: Five proteins identified as risk markers

SECRE technique paves way for new therapeutics for autoimmune diseases

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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