DNA Methylation News and Research

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DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.

Study relates DNA methylation levels to obesity

DNA methylation is a mechanism that regulates whether genes are "on" or "off" and is influenced by hereditary and environmental factors, as well as lifestyle and nutritional habits.

10 Apr 2019

Poverty can become embedded across wide swaths of the genome, study finds

A new Northwestern University study challenges prevailing understandings of genes as immutable features of biology that are fixed at conception.

4 Apr 2019

Research leads to innovative method of diagnosing rare hereditary diseases

A new sophisticated computational model, developed by scientists at Lawson Health Research Institute, is bringing an innovative method of diagnosing rare hereditary conditions.

29 Mar 2019

Researchers find little evidence for connection between Chinese Famine and T2DM epidemic

The Chinese Famine of 1959-61 has been widely interpreted as an important contributor to later epidemics of Type 2 Diabetes Mellitis, but in re-examining 17 related Chinese studies researchers at Columbia University Mailman School of Public Health and Leiden University Medical Center, found little evidence for this association.

26 Mar 2019

Ludwig scientists to share advances in cancer research at AACR Annual Meeting 2019

Ludwig Cancer Research released today the full breadth of findings to be presented by Ludwig researchers at this year's American Association for Cancer Research (AACR) Annual Meeting in Atlanta, Ga., March 29 - April 3, 2019.

22 Mar 2019

UCD researchers lead development of new urine test to detect prostate cancer

Cancer researchers at University College Dublin have led the development of a new test which uses urine to detect prostate cancer. Studies have so far shown the test to be 70% more specific for prostate cancer compared to the blood test currently used by doctors.

19 Mar 2019

A molecular epigenetic marker can predict survival of children with leukemia

A molecular epigenetic marker is important for distinguishing patients with childhood leukemia at high and low risk of relapse even at the time of diagnosis.

8 Mar 2019

Older biologic age associated with increased risk of developing breast cancer

Biologic age, a DNA-based estimate of a person's age, is associated with future development of breast cancer, according to scientists at the National Institutes of Health.

23 Feb 2019

Microbiologists identify enzyme that makes Helicobacter so adaptable

The bacterial pathogen Helicobacter pylori owes its worldwide distribution to its genetic adaptability. Ludwig-Maximilians-Universitaet Munich microbiologists have identified an enzyme that plays a vital role in the flexible control of global gene expression in the species.

13 Feb 2019

New DNA methylation GrimAge tool allows you to predict lifespan and healthspan

The Grim Reaper arrives for each of us eventually--wouldn't it be nice to know when? Now UCLA researchers have developed a new tool to help you plan ahead for your date with the Angel of Death.

13 Feb 2019

Blood cells could hold the key to aging

Blood cells could hold the key to aging, according to new research out of Case Western Reserve University School of Medicine.

8 Feb 2019

Insufficient sleep mirrored by DNA from blood leukocytes

An insufficient amount of sleep and qualitatively poor sleep are common among the general population. Prior studies have indicated that prolonged insufficient sleep and poor sleep quality are associated with a heightened risk of cardiovascular diseases, dementia and psychiatric disorders, particularly depression, yet the molecular mechanisms underlying this connection are not well known.

7 Feb 2019

Researchers identify blood-based biomarkers of Parkinson's disease

Researchers at University of California San Diego School of Medicine and Arizona State University have received funding from The Michael J. Fox Foundation for Parkinson's Research to launch a multi-year, $1.7-million effort to identify blood-based biomarkers of Parkinson's disease, which could improve care and accelerate new treatments for the neurodegenerative disorder, which affects nearly 1 million Americans, with 60,000 new cases diagnosed annually.

5 Feb 2019