DNA Methylation News and Research

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DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.

New study links perfluoroalkyl substance exposure to childhood asthma phenotypes

Study evaluated the effects of exposure to perfluoroalkyl substances on asthma phenotypes.

13 Jul 2023

THC use during pregnancy could lead to life-long health impacts for offspring

Oregon Health & Science University researchers showed that consuming THC while pregnant could potentially affect development of the fetus and lead to life-long health impacts for offspring.

6 Jul 2023

Does a healthy diet protect against dementia and slow the pace of biological aging?

Study tested whether healthy diets slowed biological aging and, thus, dementia.

6 Jul 2023

The role of pulmonary dysfunction and COVID-19 severity in the development of Long COVID

Study identified a genome-wide significant association (GWAS) for long coronavirus disease.

6 Jul 2023

Researchers pinpoint a key feature that leads to aggressive spread of colon cancer

In a significant development in the fight against fatal cancers, University of Otago researchers have pinpointed a key feature that leads to the aggressive spread of colon cancer.

26 Jun 2023

Study reveals surprising link between biological age and child development

Study explores the relationship between accelerated biological age in children, as indicated by telomere length and DNA methylation age, and various developmental outcomes. It aims to clarify the impact of accelerated biological age on growth, cognition, behavior, lung function, and puberty onset in European school-age children.

7 Jun 2023

DNAmFitAge: A new method to incorporate physical fitness into epigenetic clocks

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "DNAmFitAge: biological age indicator incorporating physical fitness."

7 Jun 2023

COLOTECT 1.0 receives market authorization from Malaysia's Medical Device Authority

Recently, BGI Genomics' COLOTECT 1.0 DNA Methylation Detection Kit for Human SDC2, ADHFE1, and PPP2R5C Genes (Real-Time PCR), Sample Pretreatment Kit for Methylation Detection, DNA Isolation Kit, Stool Sample Collection Kit have received market authorization from Malaysia's Medical Device Authority (hereinafter referred to as MDA).

6 Jun 2023

Neighborhood deprivation and depressive symptoms linked to premature aging

Feeling depressed and living in a deprived urban neighborhood could be making you age faster, according to a new study led by researchers at McMaster University.

5 Jun 2023

To what extent does prenatal folate status modify associations between early pregnancy perfluoroalkyl and polyfluoroalkyl substance exposure and birth outcomes?

Researchers evaluated the relationship between PFAS exposure during pregnancy and birth outcomes.

2 Jun 2023

Green Mediterranean diet reshapes DNA methylation, boosts metabolism

Study explores the effects of a green-MED diet enriched in polyphenols and reduced in red/processed meat on the methylome and transcriptome levels. It aims to uncover the molecular mechanisms underlying the observed metabolic improvements.

30 May 2023

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Melatonin, a hormone derived from the pineal gland, has diverse effects on cellular processes. This review explores its potential role as an epigenetic regulator, particularly in modulating DNA methylation, and suggests its use in combination therapy as a novel anticancer strategy.

30 May 2023

Groundbreaking study targets 'jumping genes' in the entire genomes of the human large intestine

The Korea Advanced Institute of Science and Technology (KAIST) and their collaborators have conducted a groundbreaking study targeting 'jumping genes' in the entire genomes of the human large intestine.

25 May 2023

Novel regulators of COPD determined by epigenetic profiling

Impaired function of lung fibroblast is considered causative for symptoms of the incurable lung disease COPD (Chronic Obstructive Pulmonary Disease).

25 May 2023

Combination of genetic and environmental factors increases the risk of cleft lip

A cleft lip or palate arises from the combined effects of genes and inflammatory risk factors experienced during pregnancy, such as smoking or infections, finds a new study led by UCL researchers.

24 May 2023

Researchers develop a computational approach to predict diabetic kidney disease

Researchers from Sanford Burnham Prebys and the Chinese University of Hong Kong have developed a computational approach to predict whether a person with type 2 diabetes will develop kidney disease, a frequent and dangerous complication of diabetes.

15 May 2023

New approaches to promote healthspan from an epigenetic perspective

A new review paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "How can we modulate aging through nutrition and physical exercise? An epigenetic approach."

10 May 2023

Silenced p16 gene can drive colorectal cancer progression

Colorectal cancer is the fourth most common and second deadliest cancer. How colorectal cancer develops is not well understood, but a team led by researchers at Baylor College of Medicine reports in the Journal of Experimental & Clinical Cancer Research that silencing the gene p16, even though the DNA itself does not change, can drive colorectal cancer progression in animal models.

10 May 2023

Does stress increase biological age?

Researchers evaluated stress-induced biological age (BA) changes among mice and humans.

4 May 2023

Environmental exposures during pregnancy can affect obesity risk differently in girls and boys, according to a study

A study published in the journal BMC Medicine describes that the risk of obesity and neurodevelopmental delay can vary between boys and girls concerning certain types of prenatal exposures. The study identifies a combination of four exposure levels that protect girls from developing these complications.

13 Apr 2023

DNA Methylation News and Research

Further Reading

New study links perfluoroalkyl substance exposure to childhood asthma phenotypes

THC use during pregnancy could lead to life-long health impacts for offspring

Does a healthy diet protect against dementia and slow the pace of biological aging?

The role of pulmonary dysfunction and COVID-19 severity in the development of Long COVID

Researchers pinpoint a key feature that leads to aggressive spread of colon cancer

Study reveals surprising link between biological age and child development

DNAmFitAge: A new method to incorporate physical fitness into epigenetic clocks

COLOTECT 1.0 receives market authorization from Malaysia's Medical Device Authority

Neighborhood deprivation and depressive symptoms linked to premature aging

To what extent does prenatal folate status modify associations between early pregnancy perfluoroalkyl and polyfluoroalkyl substance exposure and birth outcomes?

Green Mediterranean diet reshapes DNA methylation, boosts metabolism

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Groundbreaking study targets 'jumping genes' in the entire genomes of the human large intestine

Novel regulators of COPD determined by epigenetic profiling

Combination of genetic and environmental factors increases the risk of cleft lip

Researchers develop a computational approach to predict diabetic kidney disease

New approaches to promote healthspan from an epigenetic perspective

Silenced p16 gene can drive colorectal cancer progression

Does stress increase biological age?

Environmental exposures during pregnancy can affect obesity risk differently in girls and boys, according to a study

DNA Methylation eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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