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CITN selects Cytheris' CYT107 for initial clinical trials at network institutions

Cytheris SA and the Cancer Immunotherapy Trials Network, a new initiative in immunotherapy funded by the National Cancer Institute with its Central Operations and Statistical Center headquartered at Fred Hutchinson Cancer Research Center, Seattle, Washington, today announced the selection of recombinant human interleukin-7, the investigational multifunctional cytokine under development by Cytheris, as one of the first immunotherapeutic agents proposed for initial clinical trials at network institutions.

18 May 2011

NCNPR and Cancer Institute in Jackson partner for anti-cancer drug research

A new partnership to search for cancer-fighting drugs combines compound-identification and screening expertise at the University of Mississippi's National Center for Natural Products Research with the drug development and clinical-trials capabilities at the University of Mississippi Medical Center Cancer Institute.

18 May 2011

Study finds three-month TB treatment regimen just as effective as standard longer course

"Health officials on Monday celebrated a faster treatment for people who have tuberculosis but aren't infectious, after investigators found a new combination of pills knocks out the disease in three months instead of nine," the Associated Press/Seattle Times reports.

18 May 2011

Impaired ability to handle oxidative stress may contribute to asthma development

An impaired ability to handle oxidative stress that arises from exposure to secondhand smoke and other environmental triggers may contribute to the development of asthma, according to results obtained from the Shanghai Women's Health Asthma and Allergy Study. The results of the study suggest regulating the body's antioxidant defense system may play an important role in asthma prevention.

18 May 2011

Study offers new understanding of cell signaling networks tied to diabetes and cancer

Researchers at the University of Texas Medical Branch at Galveston and the University of California-San Diego School of Medicine have published a study that offers a new understanding of a protein critical to physiological processes involved in major diseases such as diabetes and cancer. This work could help scientists design drugs to battle these disorders.

18 May 2011

Anavex comments on new Alzheimer’s disease diagnostic guidelines

Anavex Life Sciences Corp. (“Anavex”) (OTCBB: AVXL) today commented on new diagnostic criteria and guidelines for Alzheimer’s disease published recently by the National Institute on Aging (NIA) and the Alzheimer’s Association, which have been updated for the first time in more than 25 years. The new guidelines discuss the importance of new technologies, including brain imaging and biomarker analysis, in research and clinical diagnosis. They describe Alzheimer’s disease at a preclinical stage, Mild Cognitive Impairment (MCI) due to Alzheimer’s disease, and dementia due to Alzheimer’s pathology.

18 May 2011

Anti-cancer drug discovery partnership formed between UMMC Cancer Institute and Natural Products Center

A new partnership to search for cancer-fighting drugs combines compound-identification and screening expertise at the University of Mississippi’s National Center for Natural Products Research with the drug development and clinical-trials capabilities at the University of Mississippi Medical Center Cancer Institute.

18 May 2011

Decision on destroying last of the stored small pox virus samples

Health experts from all over the world are to decide this week whether to hold on to the last remaining stockpiles of smallpox, one of the deadliest diseases in history – or to proceed with their destruction.

17 May 2011

Accelr8 presents initial ICU pilot study results at ATS International Conference

Accelr8 Technology Corporation announced that clinical investigators led by Ivor S. Douglas, MD/FRCP (UK) from Denver Health presented initial ICU pilot study results at the 2011 ATS International Conference.

17 May 2011

Pfizer seeks U.S. FDA, Japanese MHLW approval for crizotinib NDA to treat ALK-positive advanced NSCLC

Pfizer Inc. announced today that its New Drug Application for crizotinib, an oral first-in-class anaplastic lymphoma kinase inhibitor, has been accepted for filing and granted Priority Review status by the U.S. Food and Drug Administration and has been filed with the Japanese Ministry of Health, Labour and Welfare.

17 May 2011

Lung protein appears to play a key role in smoking-related emphysema

An international research team has identified a lung protein that appears to play a key role in smoking-related emphysema and have crafted an antibody to block its activity, Indiana University scientists reported.

17 May 2011

Pioneer of ‘organ-on-a-chip’ technology to speak at Imperial College London

The potential of microscopic organ-on-a-chip devices that mimic the way real organs work, so that scientists and engineers can model the effects of therapies more accurately, will be discussed by a pioneer in bioengineering at Imperial College London this week.

17 May 2011

Thrombolytic therapy linked to poor survival in pulmonary embolism patients with normal blood pressure

Although so-called clot-busting drugs are commonly used in the treatment of some patients with blood clots in the lungs, a new study conducted by researchers in Spain and the U.S. indicates the agents do not appear to be any more effective than traditional blood thinners for the majority of these patients.

17 May 2011

Scientists identify 'de novo' genetic mutations in autism spectrum disorder children

Scientists at the University of Washington (UW) Department of Genome Sciences have identified several sporadic or "de novo" genetic mutations in children with autism spectrum disorder. The researchers applied leading edge molecular biology techniques and massively parallel sequencing to simultaneously examine all of the protein coding portions of the genome, collectively called the exome.

17 May 2011

Scientists make human stem cells without working on human embryos

Stem cell research courts both controversy and support in the community- depending on your viewpoint.

17 May 2011

PKC-delta enzyme critical for development of insulin resistance, diabetes and fatty liver

The road to type 2 diabetes is paved with insulin resistance, a condition often associated with obesity in which the hormone begins to fail at its job helping to convert sugars to energy.

17 May 2011

'Mu opioid' receptors in the brain linked to smoking relapse

Nearly everyone who has tried to quit smoking says it's incredibly difficult, and the struggle is due in part to genetic factors. Now, a new study from the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania sheds light on how one specific genetic risk for smoking relapse may work: Some of the difficulties may be due to how many receptors, called "mu opioid" receptors, a smoker has in his or her brain.

17 May 2011

World Health Assembly begins in Geneva

As the 64th World Health Assembly gets underway in Geneva, the body will consider "an array of subjects pertaining to reforms of the organisation and its financing, vaccines, fake medicines, and influenza pandemic preparedness, as well as communicable and non-communicable diseases," Intellectual Property Watch reports.

17 May 2011

Anti-inflammatory drug celecoxib reacts with protein and induces liver cancer cells to commit suicide

The anti-inflammatory drug celecoxib, known by the brand name Celebrex, triggers liver cancer cell death by reacting with a protein in a way that makes those cells commit suicide, according to a new study.

17 May 2011

ESC calls for single co-ordinated European system to oversee evaluation, approval of medical devices

The European Society of Cardiology (ESC) is calling for a single, co-ordinated European system to oversee the evaluation and approval of medical devices. The call is being made in a paper published online in the European Heart Journal reporting on a conference held by the ESC in January 2011 looking to increase the input of medical experts in developing medical device policy.

17 May 2011

Drugs News and Research

CITN selects Cytheris' CYT107 for initial clinical trials at network institutions

NCNPR and Cancer Institute in Jackson partner for anti-cancer drug research

Study finds three-month TB treatment regimen just as effective as standard longer course

Impaired ability to handle oxidative stress may contribute to asthma development

Study offers new understanding of cell signaling networks tied to diabetes and cancer

Anavex comments on new Alzheimer’s disease diagnostic guidelines

Anti-cancer drug discovery partnership formed between UMMC Cancer Institute and Natural Products Center

Decision on destroying last of the stored small pox virus samples

Accelr8 presents initial ICU pilot study results at ATS International Conference

Pfizer seeks U.S. FDA, Japanese MHLW approval for crizotinib NDA to treat ALK-positive advanced NSCLC

Lung protein appears to play a key role in smoking-related emphysema

Pioneer of ‘organ-on-a-chip’ technology to speak at Imperial College London

Thrombolytic therapy linked to poor survival in pulmonary embolism patients with normal blood pressure

Scientists identify 'de novo' genetic mutations in autism spectrum disorder children

Scientists make human stem cells without working on human embryos

PKC-delta enzyme critical for development of insulin resistance, diabetes and fatty liver

'Mu opioid' receptors in the brain linked to smoking relapse

World Health Assembly begins in Geneva

Anti-inflammatory drug celecoxib reacts with protein and induces liver cancer cells to commit suicide

ESC calls for single co-ordinated European system to oversee evaluation, approval of medical devices

Drug Discovery - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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