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PolyMedix defensin-mimetic antibiotic compounds show antimicrobial efficacy against anthrax

PolyMedix, Inc., a biotechnology company focused on developing new therapeutic drugs to treat patients with acute infectious diseases and cardiovascular disorders, announced today that several of its defensin-mimetic antibiotic compounds have shown antimicrobial efficacy in an animal model against the bacteria that causes anthrax.

26 Apr 2011

New nano-systems capable of binding heparin as effectively as protamine

New nano-systems developed in York may eventually help patients recover from surgery without the danger of allergic reactions to drugs.

26 Apr 2011

Active Healthy Kids Canada releases 2011 Report Card on physical activity for children, youth

School's out, do you know what your kids are doing? You may want to think again if you believe they are being physically active.

26 Apr 2011

Anti-inflammatory drugs reduce effectiveness of widely used antidepressant medications

Scientists at the Fisher Center for Alzheimer's Disease Research at The Rockefeller University, led by Paul Greengard, Ph.D., and Jennifer Warner-Schmidt, Ph.D., have shown that anti-inflammatory drugs, which include ibuprofen, aspirin and naproxen, reduce the effectiveness of the most widely used class of antidepressant medications, the selective serotonin reuptake inhibitors, or SSRIs, taken for depression and obsessive-compulsive disorder and anxiety disorders.

26 Apr 2011

Experts to present research on vascular biology and disease at ATVB meetings

Nearly 1,200 experts in cardiovascular medicine, vascular biology, endocrinology, hematology and other disciplines are expected to attend the American Heart Association's Arteriosclerosis, Thrombosis and Vascular Biology 2011 Scientific Sessions, April 28-30, in Chicago, Ill.

26 Apr 2011

Ohio State Roundtable to discuss about cancer drug development

The Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute and Friends of Cancer Research are convening a high-level group of stakeholders to discuss current obstacles halting co-development of two or more experimental drugs for the treatment of cancer.

26 Apr 2011

Colorectal cancer patients with genetic mutation can benefit from new class of drugs

A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.

26 Apr 2011

Study: Women use more medications during pregnancy

Researchers from Boston University's Slone Epidemiology Center, in collaboration with the Centers for Disease Control and Prevention and Harvard School of Public Health, have reported widespread and increasing medication use among pregnant women.

26 Apr 2011

World Malaria Day opinion pieces

Andrew Mitchell, Britain's secretary of state for international development, discusses the U.K.'s approach to combating malaria around the world in a post on the Guardian's "Poverty Matters Blog."

26 Apr 2011

Unintentional prescription opioid overdose deaths have reached epidemic proportions in the U.S.

Unintentional overdose deaths in teens and adults have reached epidemic proportions in the U.S. In some 20 states in 2007 the number of unintentional drug poisoning deaths exceeded either motor vehicle crashes or suicides, two of the leading causes of injury death.

26 Apr 2011

Alkem, Karo Bio partner to license eprotirome

Karo Bio has entered into a collaboration and license agreement with the Indian pharmaceutical company Alkem Laboratories Ltd.

26 Apr 2011

Dactinomycin more effective for low-risk gestational tumor treatment

A clinical trial has sifted out the most effective single-drug chemotherapy regimen for quick-growing but highly curable cancers that arise from the placentas of pregnant women.

26 Apr 2011

In the statehouses: Localities vs. unions in Mass.; supporters to rally for SustiNet in Conn.

Massachusetts House lawmakers kick off a busy week on Beacon Hill Monday with full chamber negotiations over the state budget. ... The biggest point of contention in the budget is the DeLeo-backed provision giving cities and towns the ability to alter employee health plans without union approval. At least 50 Democrats have reportedly signed on to an amendment that would soften that provision.

26 Apr 2011

ACC/AHA release consensus document to help clinicians reduce risk of hypertension in older adults

Hypertension is very common among older adults. 64 percent of older men and 78 percent of older women have high blood pressure, placing them at heightened risk for heart disease including heart failure, stroke, coronary artery disease and atrial fibrillation, as well as chronic kidney disease and diabetes mellitus.

26 Apr 2011

Scientists identify key enzyme that destroys lung tissue in TB

Scientists have identified a key enzyme responsible for destroying lung tissue in tuberculosis, they report today in the Journal of Clinical Investigation. Drugs that inhibit this enzyme are already available, meaning that the finding could lead quickly to new treatments.

26 Apr 2011

Study: HIV infection linked to increased risk of heart failure

Patients with HIV infection without a prior history of coronary heart disease may be at a higher risk of developing heart failure, according to a report in the April 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

26 Apr 2011

Aetna achieves full pharmacy benefit management accreditation from URAC

Aetna Pharmacy Management today announced that it has been awarded full pharmacy benefit management accreditation from URAC, an independent health care accrediting organization that evaluates and monitors PBM's for quality, safety and effectiveness.

26 Apr 2011

Signaling pathway reveals mechanism for B cell differentiation in immune response

An article in Science Signaling by researchers at the RIKEN Research Center for Allergy and Immunology (RCAI) has clarified for the first time the mechanism governing differentiation of B cells into antibody-producing plasma cells. The finding establishes a role for the extracellular signal-regulated kinase (ERK) signaling pathway in B cell differentiation, a key step toward the development of B cell-targeted drugs for treatment of autoimmune diseases and allergies.

25 Apr 2011

Kadmon Pharmaceuticals and Nano Terra announce worldwide licensing agreement

Kadmon Pharmaceuticals LLC, and Nano Terra, Inc., today announced that they have entered into an agreement under which Kadmon has been granted a perpetual, worldwide exclusive license to three novel, clinical-stage product candidates owned by Nano Terra as well as rights to Nano Terra’s drug discovery platform, Pharmacomer™ Technology. The product candidates and technology platform will be transferred to a newly formed joint venture, NT Life Sciences (“NT Life”), co-owned by Kadmon and Nano Terra, which will act as the licensor and recipient of any licensing or royalty fees subject to the agreement. Terms of the agreement were not disclosed.

25 Apr 2011

Study questions suitability of anti-retroviral drugs for the young

According to a new major study one in eight children born with HIV becomes resistant to the three main classes of drugs used to suppress the virus within five years of starting treatment. This is the first major study that looks at drug resistance in 1,000 European children born with HIV. It raises questions about the suitability of anti-retroviral drugs for the young.

25 Apr 2011

Drugs News and Research

PolyMedix defensin-mimetic antibiotic compounds show antimicrobial efficacy against anthrax

New nano-systems capable of binding heparin as effectively as protamine

Active Healthy Kids Canada releases 2011 Report Card on physical activity for children, youth

Anti-inflammatory drugs reduce effectiveness of widely used antidepressant medications

Experts to present research on vascular biology and disease at ATVB meetings

Ohio State Roundtable to discuss about cancer drug development

Colorectal cancer patients with genetic mutation can benefit from new class of drugs

Study: Women use more medications during pregnancy

World Malaria Day opinion pieces

Unintentional prescription opioid overdose deaths have reached epidemic proportions in the U.S.

Alkem, Karo Bio partner to license eprotirome

Dactinomycin more effective for low-risk gestational tumor treatment

In the statehouses: Localities vs. unions in Mass.; supporters to rally for SustiNet in Conn.

ACC/AHA release consensus document to help clinicians reduce risk of hypertension in older adults

Scientists identify key enzyme that destroys lung tissue in TB

Study: HIV infection linked to increased risk of heart failure

Aetna achieves full pharmacy benefit management accreditation from URAC

Signaling pathway reveals mechanism for B cell differentiation in immune response

Kadmon Pharmaceuticals and Nano Terra announce worldwide licensing agreement

Study questions suitability of anti-retroviral drugs for the young

Drug Discovery - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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