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Discovery of DNA repair mechanism advances understanding of how human cells stay healthy

Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.

17 Apr 2024

To stop fentanyl deaths in Philadelphia, knocking on doors and handing out overdose kits

On a narrow street lined with row houses and an auto body shop in the Kensington neighborhood of North Philadelphia, Marsella Elie climbs a home's front steps and knocks hard on the door.

17 Apr 2024

Study finds microdosing LSD leads to longer sleep: Insights from a controlled trial

A phase I trial to assess the effect of micro-dosing of lysergic acid diethylamide (LSD) on the sleep.

17 Apr 2024

Machine learning reveals age-related decline in stemness across human tissues

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 7, entitled, "Evidence of a pan-tissue decline in stemness during human aging."

16 Apr 2024

Junk food-filled diet in teens may disrupt brains' memory ability for a long time

A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may disrupt their brains' memory ability for a long time.

16 Apr 2024

Common HIV drugs linked to reduced Alzheimer's disease risk

Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a major unmet medical need.

16 Apr 2024

Early life stress may underlie a pathophysiological exacerbation of postpartum depression

In a new study, a Johns Hopkins Medicine-led research team reports that social stress during adolescence in female mice later results in prolonged elevation of the hormone cortisol after they give birth.

16 Apr 2024

Study reveals novel approach to promote efficient uptake of ASOs into cancer cells

Antisense oligonucleotides (ASOs) are next-generation drugs that can treat disease by blocking the transfer of harmful messages from our genes.

16 Apr 2024

Study reveals deadly bacteria's attraction to human blood

Some of the world's deadliest bacteria seek out and feed on human blood, a newly-discovered phenomenon researchers are calling "bacterial vampirism."

16 Apr 2024

Pitt researchers uncover mechanisms behind uveal melanoma resistance

New research from the University of Pittsburgh explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient's T cells outside the body before reinfusing them, can successfully treat this rare and aggressive cancer.

16 Apr 2024

Is spousal cardiovascular disease associated with an increased risk for depression?

Whether the spouses of those affected are more likely to become depressed after such events.

16 Apr 2024

Childhood traumatic experiences may get "under the skin" later in life

A University of Michigan study has shown that traumatic experiences during childhood may get "under the skin" later in life, impairing the muscle function of people as they age.

15 Apr 2024

Texas A&M scientists elucidate how phages disarm antibiotic-resistant bacteria

Bacterial infections pose significant challenges to agriculture and medicine, especially as cases of antibiotic-resistant bacteria continue to rise.

15 Apr 2024

Study reveals shocking rise in opioid deaths among Canadian youth

Premature deaths related to opioids doubled between 2019 and 2021 across Canada, with more than 1 in 4 deaths among young adults aged 20–39 years attributable to opioids, according to new research published in CMAJ.

15 Apr 2024

Swap funds or add services? Use of opioid settlement cash sparks strong disagreements

State and local governments are receiving billions of dollars in opioid settlements to address the drug crisis that has ravaged America for decades.

15 Apr 2024

Study unlocks genetic secrets in APOEε4 carriers that could defend against Alzheimer's

Researchers utilized whole-genome sequencing and pathway analysis to uncover protective genetic variations against Alzheimer's disease in APOEε4 carriers, revealing a crucial role for extracellular matrix-related genes in mitigating the disease's progression.

15 Apr 2024

Drugs News and Research

Discovery of DNA repair mechanism advances understanding of how human cells stay healthy

To stop fentanyl deaths in Philadelphia, knocking on doors and handing out overdose kits

Study finds microdosing LSD leads to longer sleep: Insights from a controlled trial

Machine learning reveals age-related decline in stemness across human tissues

Junk food-filled diet in teens may disrupt brains' memory ability for a long time

Common HIV drugs linked to reduced Alzheimer's disease risk

Early life stress may underlie a pathophysiological exacerbation of postpartum depression

Study reveals novel approach to promote efficient uptake of ASOs into cancer cells

Study reveals deadly bacteria's attraction to human blood

Pitt researchers uncover mechanisms behind uveal melanoma resistance

Is spousal cardiovascular disease associated with an increased risk for depression?

Childhood traumatic experiences may get "under the skin" later in life

Texas A&M scientists elucidate how phages disarm antibiotic-resistant bacteria

Study reveals shocking rise in opioid deaths among Canadian youth

Swap funds or add services? Use of opioid settlement cash sparks strong disagreements

Study unlocks genetic secrets in APOEε4 carriers that could defend against Alzheimer's

Esketamine after childbirth cuts risk of postnatal depression by three-quarters

Study reveals high prevalence of menstrual migraines in U.S. women

U-M study reveals potential pathway to reverse lung fibrosis

Deciphering the molecular interactions of opioid receptors: Implications for drug design

Drug Discovery - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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