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Study sheds light on the significance of glucocorticoid receptor in drug-resistant prostate cancer

New research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by limiting the activity of coregulator proteins.

10 Apr 2024

Global increase in deaths from viral hepatitis revealed in WHO report

According to the World Health Organization (WHO) 2024 Global Hepatitis Report, the number of lives lost due to viral hepatitis is increasing.

10 Apr 2024

Deciphering cancer plasticity:Insights from MSK research

About 90% of deaths from cancer are a result of metastasis -; that is, from cancer's ability to spread from an initial primary tumor to seed new tumors throughout the body, often in the lungs, liver, and brain.

10 Apr 2024

High blood levels of TMAO predicts chronic kidney disease risk in future

New findings from Cleveland Clinic and Tufts University researchers show high blood levels of TMAO (trimethylamine N-oxide) predicts future risk of developing chronic kidney disease over time.

9 Apr 2024

Popular diabetes drugs not linked to thyroid cancer risk, study finds

CMS121 holds promise for treating metabolic diseases

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 6, entitled, "CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction."

9 Apr 2024

Researchers leverage machine-learning techniques to predict future risk of pressure injuries

Bedsores-;also known as pressure injuries-;are the fastest rising hospital-acquired condition, according to the U.S. Agency for Healthcare Research in Quality, and as a result have become the second most common reason for medical malpractice suits in the United States.

9 Apr 2024

Research identifies how leukemia develops resistance to first line treatments

Relapses in a common form of leukemia may be preventable following new research which has identified how the cancer develops resistance to first line treatments.

9 Apr 2024

Researchers elucidate how gene mutation mechanism causes autism

Researchers show how mutations of gene transcription and chromatin regulation-related genes cause autism.

9 Apr 2024

After public push, CMS curbs health insurance agents’ access to consumer SSNs

Until last week, the system that is used to enroll people in federal Affordable Care Act insurance plans inadvertently allowed access by insurance brokers to consumers' full Social Security numbers, information brokers don't need.

9 Apr 2024

Rogue immune cell found to cause poor antibody responses in chronic viral infections

Australian researchers have discovered a previously unknown rogue immune cell that can cause poor antibody responses in chronic viral infections.

9 Apr 2024

SGLT2 inhibitors: A game-changer in preventing heart failure and sudden cardiac deaths

study reveals that SGLT2 inhibitors consistently lower the risk of major adverse cardiovascular events by 9% across various patient groups, especially impacting cardiovascular death reduction, highlighting their broad therapeutic potential beyond diabetes management.

9 Apr 2024

Chronic low-level inflammation may be a contributor to both depression and heart disease

Coronary artery disease and major depression may be genetically linked via inflammatory pathways to an increased risk for cardiomyopathy, a degenerative heart muscle disease, researchers at Vanderbilt University Medical Center and Massachusetts General Hospital have found.

8 Apr 2024

Nerve ablation's varied outcomes in high blood pressure treatment

A new system that uses dehydrated alcohol to deactivate certain nerves surrounding the kidneys' arteries in order to control high blood pressure met its primary endpoint—lowering blood pressure at three months as measured with a 24-hour ambulatory systolic blood pressure monitor—in a pivotal phase 3 trial presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

IVUS guidance improves angioplasty success rates in patients with peripheral artery disease

One-year success rates from angioplasty procedures to open clogged arteries in the legs were significantly higher among patients whose procedures were guided by intravascular ultrasound (IVUS) alongside angiography compared with those whose procedures were guided by angiography alone, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

DEPOSITION trial evaluates the use of topical tranexamic acid during heart surgery

Administering tranexamic acid (TxA), a drug used to reduce bleeding during heart surgery, topically rather than intravenously did not meet its primary endpoint of reducing seizures and was stopped early due to an increased risk of bleeding events, according to research presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Novel therapeutic approach identified for overcoming resistance in B-cell leukemia

Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between 30-50%.

8 Apr 2024

ACE inhibitors show no benefit in reducing chemotherapy-induced heart damage

Patients who took an angiotensin-converting enzyme (ACE) inhibitor while undergoing cancer treatment with high-dose anthracycline chemotherapy did not show any difference in troponin T levels, a biomarker associated with heart damage, at one month after their last chemotherapy dose compared with those who did not take an ACE inhibitor, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

People who have had a heart attack or who are at risk for a heart attack and who stopped taking aspirin alongside the P2Y12 inhibitor ticagrelor one month after undergoing percutaneous coronary intervention (PCI) saw a significantly reduced risk of clinically meaningful bleeding with no increased risk of clotting-related adverse events at 12 months compared with patients who continued taking aspirin and ticagrelor for a full year, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Study: Empagliflozin shows mixed results in heart attack patients

Use of the sodium glucose cotransporter-2 (SGLT-2) inhibitor empagliflozin following a heart attack did not show a significant benefit in reducing overall heart failure hospitalizations or death from any cause, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

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Drugs News and Research

Study sheds light on the significance of glucocorticoid receptor in drug-resistant prostate cancer

Global increase in deaths from viral hepatitis revealed in WHO report

Deciphering cancer plasticity:Insights from MSK research

High blood levels of TMAO predicts chronic kidney disease risk in future

Popular diabetes drugs not linked to thyroid cancer risk, study finds

CMS121 holds promise for treating metabolic diseases

Researchers leverage machine-learning techniques to predict future risk of pressure injuries

Research identifies how leukemia develops resistance to first line treatments

Researchers elucidate how gene mutation mechanism causes autism

After public push, CMS curbs health insurance agents’ access to consumer SSNs

Rogue immune cell found to cause poor antibody responses in chronic viral infections

SGLT2 inhibitors: A game-changer in preventing heart failure and sudden cardiac deaths

Chronic low-level inflammation may be a contributor to both depression and heart disease

Nerve ablation's varied outcomes in high blood pressure treatment

IVUS guidance improves angioplasty success rates in patients with peripheral artery disease

DEPOSITION trial evaluates the use of topical tranexamic acid during heart surgery

Novel therapeutic approach identified for overcoming resistance in B-cell leukemia

ACE inhibitors show no benefit in reducing chemotherapy-induced heart damage

Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

Study: Empagliflozin shows mixed results in heart attack patients

Drug Discovery - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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