Electron Microscopy News and Research

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Biologists reveal structure of newly discovered speargun-like molecular injection systems in bacteria

Biologists from ETH Zurich have discovered speargun-like molecular injection systems in two types of bacteria and have described their structure for the first time.

7 Mar 2022

Study may pave the way for better multiple sclerosis drugs

Investigators from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have discovered how a drug for multiple sclerosis interacts with its targets, a finding that may pave the way for better treatments.

4 Mar 2022

World's first Microhub makes spatial context accessible for all

New Mica imaging platform from Leica Microsystems brings previously inaccessible experiments to all life science researchers

From Leica Microsystems GmbH 3 Mar 2022

Scientists find no connection between pandemic chilblains and SARS-CoV-2 infection

A recent study provides a better understanding of whether SARS-CoV-2 infection is linked with the occurrence of chilblains.

3 Mar 2022

Cow's milk protein can trigger inflammation in multiple sclerosis sufferers

Multiple sclerosis sufferers often complain of more severe disease symptoms after consuming dairy products. Researchers at the Universities of Bonn and Erlangen-Nuremberg have now found a possible cause for this.

1 Mar 2022

Mechanisms leading to Parkinson's disease following SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated the impact of an amyloidogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protein fragment named SFYVYSRVK (SK9) on the α-synuclein (aS) monomers and fibrils, a potential risk factor for Parkinson's disease.

28 Feb 2022

Harvard researcher develops new model system to illuminate the fundamentals of aging

Huge amounts of time and money have been devoted to finding treatments for diseases that become more common as we age, like cancer and Alzheimer's.

28 Feb 2022

Study explores the boosting of SARS-CoV-2 adenovirus vaccine-induced immunity by capsid decoration

Researchers demonstrated that decorating the capsid surface of adenovirus vaccine vectors with a newly discovered protein superglue, DogTag/DogCatcher generates potent SARS-CoV-2-specific humoral and cellular immunity.

24 Feb 2022

hAELVi cell infection model mimics SARS-CoV-2 Omicron infection in lower respiratory tract of humans

In a recent study posted to the Research Square* preprint server, which is under consideration at Scientific Reports, a team of researchers developed a novel human Alveolar Epithelial Lentivirus immortalized (hAELVi) cell infection model to estimate the replication potential of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viruses in the lower respiratory tract of humans.

23 Feb 2022

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Researchers explore the potential of mosaic receptor-binding domain nanoparticles in protective immunity against SARS-CoV-2

22 Feb 2022

Researchers unravel essential final steps in the production of mRNA

Proteins need to interact in a complex manner for a so-called "messenger RNA" (mRNA) to be created in human cells from a precursor molecule. mRNA provides a blueprint for proteins; the first vaccines against the coronavirus are also based on mRNAs.

21 Feb 2022

SARS-CoV-2 Omicron variant prompts system sciences and precision medicine

In a new review study, researchers aimed to describe the emergence of the Omicron variant, its structure, its impact on health and health systems, and the challenges that can be expected due to this variant.

21 Feb 2022

New research shines light on mysterious dynamics that define the interplay between nerves and muscle

New research co-led by a University of Ottawa Faculty of Medicine professor is shedding light on some of the mysterious dynamics that define the interplay between nerves and muscle.

17 Feb 2022

Mechanism of SARS-CoV-2 Nsp1 interaction with ribosomal complexes

In a recent study posted to the bioRxiv* preprint server, the team of researchers explored the protein-protein interaction between the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 1 (Nsp1) and host 40S and 43S ribosomal subunits.

15 Feb 2022

Novel glycation patterns help understand Omicron immune escape

A new study explores changes in the sugar structure of the SARS-CoV-2 Omicron variant, which may shed light on its immunologic escape and transmissibility characteristics.

15 Feb 2022

RNA capping mechanism of SARS-CoV-2 unveiled

In a recent study posted to the bioRxiv* preprint server, researchers elucidated the mechanism of ribonucleic acid (RNA) capping in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

14 Feb 2022

Study describes a β-CoV spike protein target for protective antibodies that may facilitate pan-β-CoV vaccine development

In a recent study published in Science Translational Medicine, researchers characterized a human antibody targeting betacoronaviruses (β-CoVs).

14 Feb 2022

Study reveals that 1PBC and niclosamide bind the same drug-binding pocket

Researchers used cryo-EM to demonstrate that 1PBC, and the drug niclosamide, both inhibitors of TMEM16 proteins, have therapeutic potential and may be used for COVID-19 treatment.

14 Feb 2022

Testes found to be a viral reservoir for SARS-CoV-2 replication

In a recent study posted to the medRxiv* pre-print server, researchers used a suite of methods to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the testis of patients who died from coronavirus disease 2019 (COVID-19) to gain insights into SARS-CoV-2 tropism inside testis and its impact on male fertility.

13 Feb 2022

Molecular cage helps researchers to get atomic-level details of key cancer protein

Acute myeloid leukemia (AML), the American Cancer Institute estimates, will affect more than 20,000 Americans this year and kill more than 11,000 of them.

11 Feb 2022

Electron Microscopy News and Research

Biologists reveal structure of newly discovered speargun-like molecular injection systems in bacteria

Study may pave the way for better multiple sclerosis drugs

World's first Microhub makes spatial context accessible for all

Scientists find no connection between pandemic chilblains and SARS-CoV-2 infection

Cow's milk protein can trigger inflammation in multiple sclerosis sufferers

Mechanisms leading to Parkinson's disease following SARS-CoV-2 infection

Harvard researcher develops new model system to illuminate the fundamentals of aging

Study explores the boosting of SARS-CoV-2 adenovirus vaccine-induced immunity by capsid decoration

hAELVi cell infection model mimics SARS-CoV-2 Omicron infection in lower respiratory tract of humans

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Researchers unravel essential final steps in the production of mRNA

SARS-CoV-2 Omicron variant prompts system sciences and precision medicine

New research shines light on mysterious dynamics that define the interplay between nerves and muscle

Mechanism of SARS-CoV-2 Nsp1 interaction with ribosomal complexes

Novel glycation patterns help understand Omicron immune escape

RNA capping mechanism of SARS-CoV-2 unveiled

Study describes a β-CoV spike protein target for protective antibodies that may facilitate pan-β-CoV vaccine development

Study reveals that 1PBC and niclosamide bind the same drug-binding pocket

Testes found to be a viral reservoir for SARS-CoV-2 replication

Molecular cage helps researchers to get atomic-level details of key cancer protein

Life Science Microscopy eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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