Epigenetics News and Research

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Epigenetics is the study of chemical reactions that influence gene expression, through activation or deactivation of genes at specific times and locations.

New approaches to treating lung cancer patients in New Mexico

This year, more than 158,000 Americans are expected to die from lung cancer. That's a staggering number: it's more than all the deaths expected from breast, prostate, colon, rectum, bladder and skin cancers combined.

26 Oct 2015

Improved results yielded from new ChIP-seq protocol

Chromatrap®, a business unit of Porvair Sciences, has developed a new protocol that further extends the many advantages of its popular Chromatin Immunoprecipitation Sequencing (ChIP-seq) assay kits.

From Chromatrap® - Porvair Sciences Ltd 23 Oct 2015

New research seeks to improve understanding of how breast cancer starts

Dr Michalak was awarded a highly competitive, four-year career development fellowship from the National Breast Cancer Foundation for her research into breast stem cells. The funding is helping to further her research, which seeks to improve our understanding of how breast cancer starts.

20 Oct 2015

New genetic discovery could lead to better treatment for X-linked diseases

Think back to middle school biology class, when you learned that boys have an X and a Y chromosome inside each cell, and girls have two X's.

20 Oct 2015

Baylor study identifies biomarker that could help determine treatment strategies for colorectal cancer patients

Researchers at Baylor Research Institute have identified a small RNA molecule that appears to enable certain colorectal cancers to become especially aggressive, resistant to treatment and likely to migrate and invade normal tissue.

19 Oct 2015

BET protein family plays key role in regulation of normal neuronal development and function

Regulation of a family of brain proteins known as bromodomain and extra-terminal domain containing transcription regulators (BETs) plays a key role in normal cognition and behavior, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published advanced online on September 21 and in print October 19 in The Journal of Experimental Medicine.

19 Oct 2015

NEB releases new NEBNext Ultra II DNA Library Prep Kit

New England Biolabs today announced the release of the NEBNext Ultra II DNA Library Prep Kit for Illumina next generation sequencing systems. The new Ultra II kit substantially improves upon its predecessor to produce libraries of both higher quality and higher yield from a variety of sample types, including challenging ones, such as formalin-fixed, paraffin-embedded (FFPE) samples and those containing low amounts of input DNA.

From New England Biolabs 16 Oct 2015

NIH's BCERP launches Columbia Mailman School & Columbia University Medical Center site

Columbia University's Mailman School of Public Health and Columbia University Medical Center together are one of six new sites being launched by the National Institutes of Health's Breast Cancer and Environment Research Program (BCERP).

16 Oct 2015

How important is a mother’s diet before pregnancy? An interview with Dr Matt Silver

In humans, much is already known about the impact of maternal undernutrition during pregnancy, and its impact on growth, development and disease throughout the life course. However, until recently little was known about the effects of the nutritional environment around the time of conception.

14 Oct 2015

Clinical study results of VolitionRx's NuQ test for pancreatic cancer published in Clinical Epigenetics

VolitionRx Limited today announced that full results from a completed clinical study of its NuQ blood-based test for early stage pancreatic cancers have been published in the online issue of Clinical Epigenetics, the official journal of the Clinical Epigenetics Society.

14 Oct 2015

Blocking the production of CHD4 protein may help increase effectiveness of AML treatments

Preclinical experiments led by a team of researchers at VCU Massey Cancer Center have shown that blocking the production of a protein known as chromodomain helicase DNA-binding protein 4 (CHD4) may help increase the effectiveness of first-line treatments for acute myeloid leukemia (AML), a particularly lethal blood cancer that is increasing in incidence among older adults.

14 Oct 2015

ASF launches Autism Sisters Project to accelerate research into 'Female Protective Effect'

The Autism Science Foundation, a not-for-profit organization dedicated to supporting and funding autism research, today announced the launch of the Autism Sisters Project, a new initiative that will give unaffected sisters of individuals with autism the opportunity to take an active role in accelerating research into the "Female Protective Effect."

14 Oct 2015

Research: Epigenetic factor reduces sensitivity of breast cancer cells to common cancer drug

A surprising, paradoxical relationship between a tumor suppressor molecule and an oncogene may be the key to explaining and working around how breast cancer tumor cells become desensitized to a common cancer drug, found researchers at the Perelman School of Medicine at the University of Pennsylvania.

13 Oct 2015

Penn researchers lay groundwork for developing lncRNA-based tools for new cancer treatment

Growing insights about a significant, yet poorly understood, part of the genome - the "dark matter of DNA" -- have fundamentally changed the way scientists approach the study of diseases.

13 Oct 2015

Prostate Cells Undergo 'Reprogramming' To Form Tumors, Study Finds

Scientists have gained a key insight into how prostate tumors get their start - not by rewriting the normal DNA code, but by reprogramming the master regulator of genes in prostate cells to drive malignant growth.

12 Oct 2015

Scientists can now use skin samples from older patients to grow brain cells

For the first time, scientists can use skin samples from older patients to create brain cells without rolling back the youthfulness clock in the cells first. The new technique, which yields cells resembling those found in older people's brains, will be a boon to scientists studying age-related diseases like Alzheimer's and Parkinson's.

9 Oct 2015

Scientists map EGFRvIII mutant that causes brain cancer

A team of Ludwig Cancer Research scientists has mapped out how a mutant version of the epidermal growth factor receptor (EGFR) known as EGFRvIII specifically drives critical processes that alter the reading of the genome to fuel the growth of the brain cancer glioblastoma multiforme (GBM) and--most important--how each process is linked to the other.

9 Oct 2015

Father’s life experiences can affect health, development of both children and grandchildren

If you have diabetes, or cancer or even heart problems, maybe you should blame it on your dad's behaviour or environment. Or even your grandfather's.

9 Oct 2015

Penn study forms basis for new treatment approaches for Sezary syndrome

Sezary syndrome (SS), an aggressive leukemia of mature T cells, is more complicated at a molecular level than ever suspected, according to investigators from the Perelman School of Medicine at the University of Pennsylvania.

8 Oct 2015

New studies suggest ways to improve cancer care by inhibiting oncogenes, boosting tumor-suppressor activity

Two new studies by cancer scientists at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) suggest new approaches for treating cancer by inhibiting overactive cancer-promoting genes and by enhancing the activity of sluggish tumor-suppressor genes.

7 Oct 2015

Epigenetics News and Research

Further Reading

New approaches to treating lung cancer patients in New Mexico

Improved results yielded from new ChIP-seq protocol

New research seeks to improve understanding of how breast cancer starts

New genetic discovery could lead to better treatment for X-linked diseases

Baylor study identifies biomarker that could help determine treatment strategies for colorectal cancer patients

BET protein family plays key role in regulation of normal neuronal development and function

NEB releases new NEBNext Ultra II DNA Library Prep Kit

NIH's BCERP launches Columbia Mailman School & Columbia University Medical Center site

How important is a mother’s diet before pregnancy? An interview with Dr Matt Silver

Clinical study results of VolitionRx's NuQ test for pancreatic cancer published in Clinical Epigenetics

Blocking the production of CHD4 protein may help increase effectiveness of AML treatments

ASF launches Autism Sisters Project to accelerate research into 'Female Protective Effect'

Research: Epigenetic factor reduces sensitivity of breast cancer cells to common cancer drug

Penn researchers lay groundwork for developing lncRNA-based tools for new cancer treatment

Prostate Cells Undergo 'Reprogramming' To Form Tumors, Study Finds

Scientists can now use skin samples from older patients to grow brain cells

Scientists map EGFRvIII mutant that causes brain cancer

Father’s life experiences can affect health, development of both children and grandchildren

Penn study forms basis for new treatment approaches for Sezary syndrome

New studies suggest ways to improve cancer care by inhibiting oncogenes, boosting tumor-suppressor activity

Genetics & Genomics - Second Edition eBook

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Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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