Epigenetics News and Research

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Epigenetics is the study of chemical reactions that influence gene expression, through activation or deactivation of genes at specific times and locations.

New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

New research from Mayo Clinic's Center for Individualized Medicine finds that patients with ASXL1-mutant chronic myelomonocytic leukemia -; an uncommon type of cancer of the bone marrow -; have distinctive epigenetic changes that can activate harmful genes and cause the cancer to grow faster.

18 Mar 2022

Epigenetic changes could be a biomarker for early detection of type 1 diabetes

Children who develop type 1 diabetes show epigenetic changes in the cells of their immune system already before the antibodies of the disease are detected in their blood.

16 Mar 2022

A medium-chain fatty acid may help protect against heart attack injuries

A medium-chain fatty acid found in energy drinks might one day help protect against heart attack injuries.

9 Mar 2022

Scientists shed light on placenta's role in transferring vitamin D to fetus during pregnancy

Scientists have shed new light on the role of the placenta in managing the relationships between maternal vitamin D and fetal development, according to a study published today in eLife.

8 Mar 2022

Slowing down the DNA replication speed increases cell reprogramming efficiency

Adult cells in our body can only give rise to the same cell type. For example, a skin cell cannot give rise to a muscle cell but to skin cells only.

7 Mar 2022

Buccal cell epigenetic biomarkers may predict preterm birth

A signature found in the cheek cells of mothers and fathers of preterm infants may help develop a test to determine whether a pregnancy may end too early.

1 Mar 2022

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram themselves in an attempt to suppress autoimmune T cell responses.

28 Feb 2022

Study shows the impact of gender-affirming hormone therapy on epigenetic signature of genes

Gender-affirming hormone therapy could influence the way a person's genes are turned on or off, according to a new study.

28 Feb 2022

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Researchers emphasized the need to take on a holistic and unbiased approach to develop a universal vaccine for coronaviruses, including SARS-CoV-2, which is a biomedical priority during the ongoing COVID-19 pandemic.

28 Feb 2022

New stem cell model could help map out the key genomic changes during early development

Researchers from the Babraham Institute have today published their latest work in the journal Cell Stem Cell describing a new subset of human embryonic stem cells that closely resemble the cells present at the genomic 'wake up call' of the 8-cell embryo stage in humans.

24 Feb 2022

Researchers identify a powerful combination of antivirals to treat COVID-19

Researchers at the University of Maryland School of Medicine and University of Pennsylvania Perelman School of Medicine have identified a powerful combination of antivirals to treat COVID-19.

14 Feb 2022

CECR2 gene inhibition prevents triple-negative breast cancer from metastasizing, study shows

A new study by researchers at Yale Cancer Center shows inhibition of the CECR2 gene prevents triple-negative breast cancer from advancing or metastasizing.

2 Feb 2022

New study to help understand the effect of cancer medicine

When the muscles become acidic after doing too many press-ups, squats or cycling to work, it is because of lactic acid.

21 Jan 2022

UBR7 protein acts as a histone chaperone during DNA replication, study finds

The protein UBR7 acts as a histone chaperone, regulating histone re-deposition at specific sites during DNA replication, according a recent study published in The EMBO Journal.

20 Dec 2021

Mutations in histone regulator protein linked to rare neurodevelopmental disorder, cancers

Mutations in a histone regulator protein are linked to both a rare neurodevelopmental disorder and to some cancers, according to a study published in the journal Genes and Development.

16 Dec 2021

Chronic exposure to particulate matter linked with high blood pressure

According to the WHO, air pollution is the greatest health risk worldwide, accounting for more than 4.2 million deaths annually.

4 Dec 2021

Inhibiting epigenetic modification could be key to reducing cancer metastasis

Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.

10 Nov 2021

Researchers find a new way to analyze diseased and healthy cells from brain tumor patients

Scientists studying the most common and aggressive type of brain tumor in adults have discovered a new way of analyzing diseased and healthy cells from the same patient.

22 Oct 2021

CAR-T cell treatment's efficacy in hematological malignancies predicted by epigenetics

One in five cancers affects blood cells and lymph nodes, causing leukemias and lymphomas, respectively. Although their treatment with drugs has led to a great advance in their cure, there are cases where there is no clinical response or resistance to them is generated.

21 Oct 2021

Discovery could help develop a new treatment strategy for patients with melanoma

A new study led by Yale Cancer Center researchers shows that the enzyme KDM5B suppresses anti-melanoma immunity.

20 Oct 2021

Epigenetics News and Research

Further Reading

New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

Epigenetic changes could be a biomarker for early detection of type 1 diabetes

A medium-chain fatty acid may help protect against heart attack injuries

Scientists shed light on placenta's role in transferring vitamin D to fetus during pregnancy

Slowing down the DNA replication speed increases cell reprogramming efficiency

Buccal cell epigenetic biomarkers may predict preterm birth

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

Study shows the impact of gender-affirming hormone therapy on epigenetic signature of genes

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

New stem cell model could help map out the key genomic changes during early development

Researchers identify a powerful combination of antivirals to treat COVID-19

CECR2 gene inhibition prevents triple-negative breast cancer from metastasizing, study shows

New study to help understand the effect of cancer medicine

UBR7 protein acts as a histone chaperone during DNA replication, study finds

Mutations in histone regulator protein linked to rare neurodevelopmental disorder, cancers

Chronic exposure to particulate matter linked with high blood pressure

Inhibiting epigenetic modification could be key to reducing cancer metastasis

Researchers find a new way to analyze diseased and healthy cells from brain tumor patients

CAR-T cell treatment's efficacy in hematological malignancies predicted by epigenetics

Discovery could help develop a new treatment strategy for patients with melanoma

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