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Researchers one step closer to finding treatment for dengue fever

Researchers one step closer to finding treatment for dengue fever

There have been several news reports that the world's first dengue vaccine will be available next year. However, the latest clinical trials show that the vaccine only provides a protection of around 50 per cent for DENV-2 and DENV-1, which are commonly found in Singapore. [More]
Researchers discover new vaccine targets to combat malaria

Researchers discover new vaccine targets to combat malaria

Researchers have discovered new vaccine targets that could help in the battle against malaria. Taking a new, large-scale approach to this search, researchers tested a library of proteins from the Plasmodium falciparum parasite with antibodies produced by the immune systems of a group of infected children. [More]
FDA approves use of Imbruvica to treat patients with chronic lymphocytic leukemia

FDA approves use of Imbruvica to treat patients with chronic lymphocytic leukemia

The U.S. Food and Drug Administration today expanded the approved use of Imbruvica (ibrutinib) to treat patients with chronic lymphocytic leukemia (CLL) who carry a deletion in chromosome 17 (17p deletion), which is associated with poor responses to standard treatment for CLL. Imbruvica received a breakthrough therapy designation for this use. [More]
Findings reveal new way to identify non-antibiotic drugs that could help curb bacterial infections

Findings reveal new way to identify non-antibiotic drugs that could help curb bacterial infections

About 100 drugs already approved by the U.S. Food and Drug Administration (FDA) for other purposes can also prevent the growth of certain bacterial pathogens inside human cells, including those that cause Legionnaires' disease, brucellosis, and Mediterranean spotted fever. [More]
Biogen Idec receives marketing authorization from EC for multiple sclerosis drug

Biogen Idec receives marketing authorization from EC for multiple sclerosis drug

Today Biogen Idec announced that the European Commission (EC) has granted marketing authorization for PLEGRIDY (peginterferon beta-1a) as a treatment for adults with relapsing-remitting multiple sclerosis (RRMS), the most common form of multiple sclerosis (MS). [More]
Researchers examine association between ritual circumcision procedure and HSV-1 in infants

Researchers examine association between ritual circumcision procedure and HSV-1 in infants

A rare procedure occasionally performed during Jewish circumcisions that involves direct oral suction is a likely source of herpes simplex virus type 1 (HSV-1) transmissions documented in infants between 1988 and 2012, a literature review conducted by Penn Medicine researchers and published online in the Journal of the Pediatric Infectious Disease Society found. [More]

Newcomer among arboviruses: The zika virus

In the group of viruses that includes dengue and chikungunya, a newcomer now has people talking about it. Also originating in Africa, zika was isolated in humans in the 1970s. Several years earlier, only a few human cases had been reported. [More]
Brown recluse spider bites increases this summer, say toxicologists

Brown recluse spider bites increases this summer, say toxicologists

Vanderbilt medical toxicologists are reporting an increase in patients seen with brown recluse spider bites this summer. [More]
FDA approves Ryanodex for treatment of malignant hyperthermia linked with anesthesia

FDA approves Ryanodex for treatment of malignant hyperthermia linked with anesthesia

Eagle Pharmaceuticals, Inc. today announced the U. S. Food and Drug Administration (FDA) has approved Ryanodex® (dantrolene sodium) for injectable suspension indicated for the treatment of malignant hyperthermia (MH), along with the appropriate supportive measures. [More]
Zydelig gets FDA approval for treatment of patients with three types of blood cancers

Zydelig gets FDA approval for treatment of patients with three types of blood cancers

The U.S. Food and Drug Administration today approved Zydelig (idelalisib) to treat patients with three types of blood cancers. [More]
Immunosignaturing holds promise for accurate diagnosis of Valley Fever

Immunosignaturing holds promise for accurate diagnosis of Valley Fever

On July 5, 2011, a massive wall of dust, ("haboob," in Arabic), blanketed Phoenix, Arizona, creating an awesome spectacle, (or stubborn nuisance, depending on your perspective). Dust storms are a common occurrence in the arid desert environments of the American Southwest. [More]
Viewpoints: Problems in training docs; impact of HHS' territory decision; what Halbig decision might mean

Viewpoints: Problems in training docs; impact of HHS' territory decision; what Halbig decision might mean

ast week's burst of world disorder was ideal for a news dump, and the White House didn't disappoint: On no legal basis, all 4.5 million residents of the five U.S. territories were quietly released from ObamaCare. [More]
Chikungunya virus transmission occurs in Florida for the first time

Chikungunya virus transmission occurs in Florida for the first time

The chikungunya virus, which is transmitted to people by mosquitoes (Aedes aegypti and Aedes albopictus), was found for the first time in the Americas on islands in the Caribbean in December 2013. Yesterday, the first case of chikungunya in the continental United States was reported in a man from Florida who had not recently travelled outside the United States. [More]
Researchers use anti-tank Javelin missile detector to identify malaria parasites in blood

Researchers use anti-tank Javelin missile detector to identify malaria parasites in blood

State-of-the-art military hardware could soon fight malaria, one of the most deadly diseases on the planet. Researchers at Monash University and the University of Melbourne have used an anti-tank Javelin missile detector, more commonly used in warfare to detect the enemy, in a new test to rapidly identify malaria parasites in blood. [More]
FDA designated Astellas’ isavuconazole as QIDP for treatment of invasive candidiasis

FDA designated Astellas’ isavuconazole as QIDP for treatment of invasive candidiasis

Astellas today announced that the U.S. Food and Drug Administration (FDA) designated isavuconazole as a Qualified Infectious Disease Product (QIDP) for the treatment of invasive candidiasis, a life-threatening, invasive fungal infection. [More]
USAMRIID provides on-site laboratory support to current Ebola outbreak

USAMRIID provides on-site laboratory support to current Ebola outbreak

Analysis of clinical samples from suspected Lassa fever cases in Sierra Leone showed that about two-thirds of the patients had been exposed to other emerging diseases, and nearly nine percent tested positive for Ebola virus. [More]
Cryptococcus gattii evolves as it spreads to temperate climates

Cryptococcus gattii evolves as it spreads to temperate climates

Cryptococcus gattii, a virulent fungus that has invaded the Pacific Northwest is highly adaptive and warrants global "public health vigilance," according to a study by an international team led by the Translational Genomics Research Institute. [More]
Paracetamol safety and osteoarthritis: an interview with Professor David Hunter, University of Sydney

Paracetamol safety and osteoarthritis: an interview with Professor David Hunter, University of Sydney

Firstly, paracetamol has been the first-line recommended treatment for osteoarthritis pain for very many years and, secondly, it is readily available over the counter and can be bought in relatively large quantities. [More]
Medac Pharma's Rasuvo injection gets FDA approval for RA, pJIA and psoriasis

Medac Pharma's Rasuvo injection gets FDA approval for RA, pJIA and psoriasis

Medac Pharma, Inc., a privately held pharmaceutical company focused on the development of new molecules and improving the effectiveness of existing medicines, announced that the U.S. Food and Drug Administration has approved Rasuvo, a subcutaneous injectable methotrexate (MTX) therapy delivered in an auto-injector for rheumatoid arthritis (RA), polyarticular-course juvenile idiopathic arthritis (pJIA) and psoriasis. [More]
CYD-TDV vaccine shows moderate protection against dengue in Asian children

CYD-TDV vaccine shows moderate protection against dengue in Asian children

The first dengue vaccine candidate (CYD-TDV) to reach phase 3 clinical testing has shown moderate protection (56%) against the disease in Asian children, according to new research published in The Lancet. [More]