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Fibrosis is the growth of fibrous tissue.
Preimplantation genetic screening using next generation sequencing: an interview with Dr Luis Alcaraz

Preimplantation genetic screening using next generation sequencing: an interview with Dr Luis Alcaraz

PGS, Preimplantation Genetic Screening, is a genetic test that analyses biopsied cells from embryos produced by in vitro fertilization (IVF) techniques. PGS determines whether the embryos are chromosomally normal (euploid) or not (aneuploid), thus giving the chance to transfer chromosomally normal embryos that are more apt to successfully implant and develop into a pregnancy. [More]
VUMC receives $11 million renewal grant to advance pulmonary fibrosis research

VUMC receives $11 million renewal grant to advance pulmonary fibrosis research

Vanderbilt University Medical Center has received an $11 million program project renewal grant from the National Heart, Lung and Blood Institute to study the genetics and underlying biological mechanisms that lead to idiopathic pulmonary fibrosis (IPF). [More]
Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Food provides us with a variety of substances we need to maintain life. These substances are essential nutrients and are classified as macronutrients (water, protein, fats, and carbohydrates) and micronutrients (vitamins and minerals). [More]
Penn researchers uncover strategy to reverse effects of dyskeratosis congenita

Penn researchers uncover strategy to reverse effects of dyskeratosis congenita

Dyskeratosis congenita, or DC, is a rare, inherited disease for which there are limited treatment options and no cure. [More]
Hydrothermal DMR results show promise in treatment of type 2 diabetes

Hydrothermal DMR results show promise in treatment of type 2 diabetes

Fractyl Laboratories Inc. (Fractyl) announced today publication of data in the current issue of Diabetes Care from the Company’s first-in-human study of RevitaTM duodenal mucosal resurfacing (Revita DMR). [More]
Study explains long-term pulmonary outcomes among childhood cancer survivors

Study explains long-term pulmonary outcomes among childhood cancer survivors

A team of researchers from nine leading academic hospitals and research centers have published a paper in the early online edition of the journal Cancer that describes pulmonary outcomes among childhood cancer survivors. [More]
New disease gene linked to shortened telomeres appears to raise risk of pulmonary fibrosis-emphysema

New disease gene linked to shortened telomeres appears to raise risk of pulmonary fibrosis-emphysema

Johns Hopkins researchers say they have identified a new disease gene that, when mutated, appears to increase the risk in a small number of people of developing emphysema and a lung-scarring condition known as pulmonary fibrosis. [More]
UH biologists developing strategies to help regenerate heart muscle cell formation

UH biologists developing strategies to help regenerate heart muscle cell formation

Cardiovascular diseases are the leading cause of death in the U.S. With one in every four deaths occurring each year, the five-year survival rate after a heart attack is worse than most cancers. [More]
Scientists link malfunctioning molecular pathways to specific heart abnormalities in SCA

Scientists link malfunctioning molecular pathways to specific heart abnormalities in SCA

Patients with sickle cell anemia (SCA) develop heart complications and nearly a quarter die a sudden death. Now, researchers have linked malfunctioning molecular pathways to specific heart anomalies in SCA that result from progressive fibrosis and result in sudden death. [More]
Reproductive age-related changes in ovarian environment may contribute to infertility

Reproductive age-related changes in ovarian environment may contribute to infertility

Women's decreased ability to produce healthy eggs as they become older may be due to excessive scarring and inflammation in their ovaries, reports a new Northwestern Medicine study in mice. [More]
Increased treatment for HCV in Rhode Island could help eradicate disease by 2030

Increased treatment for HCV in Rhode Island could help eradicate disease by 2030

A new Brown University study projects that increasing the number of Rhode Islanders treated every year for hepatitis C virus infection (HCV) to about 2,000 by 2020 would reduce cases by 90 percent and prevent more than 70 percent of expected liver-related deaths in the state by 2030. [More]
Sleep-disordered breathing promotes progression of pediatric NAFLD to NASH

Sleep-disordered breathing promotes progression of pediatric NAFLD to NASH

Studies have shown that obstructive sleep apnea and low nighttime oxygen, which result in oxidative stress, are associated with the progression of non-alcoholic fatty liver disease (NAFLD) in adults. [More]
New lung scanning platform holds potential to improve treatment for people with lung disease

New lung scanning platform holds potential to improve treatment for people with lung disease

New lung scanning technology developed at Monash University has the potential to transform treatment for millions of people with lung disease in Australia and around the world. [More]
Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

New research from University College London, Moorfields Eye Hospital and Duke University School of Medicine has identified a gene that drives scarring, together with a rapidly translatable therapy, for the UK's most common cause of blinding conjunctivitis. [More]
Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Mucous membrane pemphigoid is an autoimmune disease that causes inflammation and scarring in mucosal tissues. Affected individuals frequently exhibit scarring in the eye, which can lead to blindness in as many as 20% of patients. [More]
Australian researchers use novel Nanolive 3D Cell Explorer for nanotoxicity research

Australian researchers use novel Nanolive 3D Cell Explorer for nanotoxicity research

The Nanolive 3D Cell Explorer is a new and unique instrument using revolutionary technology that affords researchers a view inside living cells like never before. [More]
Scientists use Regeneration Intelligence to assess perturbation status of many signaling pathways

Scientists use Regeneration Intelligence to assess perturbation status of many signaling pathways

Insilico Medicine, Inc in collaboration with scientists from Atlas Regeneration, Inc, Vision Genomics, Inc and Howard University published two research papers on fibrosis in the lung and liver and fibrotic signatures in glaucoma. [More]
Researchers identify new mechanisms capable of suppressing propagation of HCV

Researchers identify new mechanisms capable of suppressing propagation of HCV

Researchers at Osaka University, Japan uncovered the mechanisms that suppress the propagation of the hepatitis C virus (HCV) with the potential of improving pathological liver conditions. [More]
Groundbreaking research opens door for prevention of cardiac fibrosis

Groundbreaking research opens door for prevention of cardiac fibrosis

Groundbreaking research from the University of Alberta and McGill University has opened the door towards the future prevention of cardiac fibrosis—a condition leading to heart failure for which there is currently no treatment. [More]
New screen-and-treat programme for hepatitis B may thwart deadly complications of disease

New screen-and-treat programme for hepatitis B may thwart deadly complications of disease

Research into Africa's first 'screen-and-treat' programme for hepatitis B suggests the initiative may reduce deadly complications of the virus. [More]
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