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Fibrosis is the growth of fibrous tissue.
Nanoparticle exposure can trigger dormant viruses in lung tissue cells

Nanoparticle exposure can trigger dormant viruses in lung tissue cells

Nanoparticles from combustion engines can activate viruses that are dormant in lung tissue cells. This is the result of a study by researchers of Helmholtz Zentrum München, a partner in the German Center for Lung Research, which has now been published in the journal 'Particle and Fibre Toxicology'. [More]
HUB and Dutch health insurance companies to test use of organoid technology for CF treatment

HUB and Dutch health insurance companies to test use of organoid technology for CF treatment

Hubrecht Organoid Technology (HUB), and the health insurance companies CZ, Zilveren Kruis, and Menzis announced today that they will start a €3 million validation trial for use of HUB Organoid Technology to test if it can be used to determine the response of Cystic Fibrosis (CF) patients to new drug therapies. [More]
UNC Catalyst aims to provide knowledge and research tools to tackle rare diseases

UNC Catalyst aims to provide knowledge and research tools to tackle rare diseases

Freely giving researchers the tools and knowledge to tackle rare and orphaned diseases is the mission of UNC Catalyst, a new endeavor the University of North Carolina at Chapel Hill has launched with a $2 million grant from the Eshelman Institute for Innovation. [More]
Giving polycystic kidney disease the bump

Giving polycystic kidney disease the bump

We launched this campaign at the beginning of October 2016. It's the first time that we've ever had a campaign of this size and scope. It's a European campaign in multiple languages that's coordinated by six of the organizations that represent PKD patients in Europe. [More]
Study reports volume and cost of in-home care for children with special medical conditions

Study reports volume and cost of in-home care for children with special medical conditions

U.S. families provide nearly $36 billion annually in uncompensated medical care at home to children who have special health care needs, such as muscular dystrophy and cystic fibrosis, according to a large national study. [More]
Study tracks parents' unpaid time assisting children with special health care needs

Study tracks parents' unpaid time assisting children with special health care needs

About half of U.S. children with special health care needs -- 5.6 million children -- receive medical care from uncompensated family members worth billions of dollars, finds a large national study led by Boston Children's Hospital and the University of Southern California (USC). [More]
New class of monocyte cells with strange morphology may cause fibrosis

New class of monocyte cells with strange morphology may cause fibrosis

Scientists at the Immunology Frontier Research Center (IFReC) at Osaka University, Japan, report a new group of monocytes they call SatM. [More]
High-fat, low-sugar diet prior to imaging can help reduce uncertainty in diagnosing cardiac sarcoidosis

High-fat, low-sugar diet prior to imaging can help reduce uncertainty in diagnosing cardiac sarcoidosis

Researchers at the University of Illinois at Chicago were able to reduce uncertainty in diagnosing cardiac sarcoidosis by having patients consume a high-fat, low-sugar diet for 72 hours prior to diagnostic imaging. [More]
Scientists discover possible way to stop activation of proteins known to cause age-related diseases

Scientists discover possible way to stop activation of proteins known to cause age-related diseases

Researchers at the University of Surrey, in collaboration with the Universities of Reading and Cologne, and the Royal Berkshire Hospital, have discovered that it is possible to stop the activation of a group of proteins (NADPH Oxidase) known to cause most of the diseases of ageing. [More]
IPF diagnosis: how do patients feel about the discussion with their physician?

IPF diagnosis: how do patients feel about the discussion with their physician?

IPF (Idiopathic Pulmonary Fibrosis) is a difficult disease to diagnose. Many patients will experience many visits to the doctor and some may even be told they have a different respiratory condition before they finally get the correct diagnosis that... [More]
Researchers identify protein that degrades and inhibits infectious biofilms

Researchers identify protein that degrades and inhibits infectious biofilms

Many infectious pathogens are difficult to treat because they develop into biofilms, layers of metabolically active but slowly growing bacteria embedded in a protective layer of slime, which are inherently more resistant to antibiotics. [More]
Researchers crack genetic code of lung tissues to identify novel targets for treating IPF

Researchers crack genetic code of lung tissues to identify novel targets for treating IPF

Researchers cracked the complete genetic code of individual cells in healthy and diseased human lung tissues to find potential new molecular targets for diagnosing and treating the lethal lung disease Idiopathic Pulmonary Fibrosis (IPF). [More]
New drug treatment can override genetic fault that causes choroideremia

New drug treatment can override genetic fault that causes choroideremia

Researchers with funding from Fight for Sight have demonstrated that a new drug treatment for cystic fibrosis and Duchenne muscular dystrophy can override a genetic fault that causes choroideremia – a severe blinding disorder. [More]
Newcastle scientists develop promising new test to identify patients with rare liver disease

Newcastle scientists develop promising new test to identify patients with rare liver disease

Newcastle scientists and medics have developed a promising new test to identify patients with a rare liver disease who will not respond to standard treatment, allowing earlier intervention with alternatives. [More]
Elucigene collaborates with Congenica to develop new NGS kit for cystic fibrosis

Elucigene collaborates with Congenica to develop new NGS kit for cystic fibrosis

The emergence of new therapies that treat the causes of cystic fibrosis are creating an imperative for more accurate variant analysis. [More]
New UGA research finds pathogen's motility activates immune response

New UGA research finds pathogen's motility activates immune response

Until now, a pathogen's ability to move through the body has been overlooked as a possible trigger of immune response, but new research from the University of Georgia College of Veterinary Medicine found that motility will indeed alarm the host and activate an immune response. [More]
Cigarette smoking may lead to fibrosis in the heart and kidneys, study reveals

Cigarette smoking may lead to fibrosis in the heart and kidneys, study reveals

Smoking may lead to fibrosis in the heart and kidneys and can worsen existing kidney disease, according to a new study. [More]
New three-dimensional map of cystic fibrosis protein offers new insights to treating fatal disease

New three-dimensional map of cystic fibrosis protein offers new insights to treating fatal disease

Rockefeller scientists have created the first three-dimensional map of the protein responsible for cystic fibrosis, an inherited disease for which there is no cure. [More]
MILabs to provide Adaptive X-ray CT system to UAB for advancing pulmonary research

MILabs to provide Adaptive X-ray CT system to UAB for advancing pulmonary research

MILabs will provide an advanced U-CTUHR microCT system to the Cystic Fibrosis Research Center (CFRC) at the University of Alabama at Birmingham (UAB). [More]
UL researchers secure funding for new cystic fibrosis device

UL researchers secure funding for new cystic fibrosis device

A medical device for Cystic Fibrosis (CF) sufferers which lessens their exposure to infections resulting in fewer doctors’ visits, reduced antibiotic usage and shorter hospital stays, is expected to be market ready within two years. [More]
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