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Researchers develop single molecule test for detecting methylated DNA

Collaborators from Mayo-Illinois Alliance for Technology Based Healthcare have developed a new, single molecule test for detecting methylated DNA. Methylation -- the addition of a methyl group of molecules to a DNA strand -- is one of the ways gene expression is regulated.

15 Mar 2013

UNM scientists identify chemical compound that appears to control cell metastases

It's the spread of the original cancer tumor that kills most people. That's why cancer researchers vigorously search for drugs that can prevent metastases, the spread of cancer. The research team co-led by Angela Wandinger-Ness, PhD, and Larry Sklar, PhD, at the University of New Mexico Cancer Center has found a chemical compound that appears to control cell migration and adhesion, two important characteristics of metastatic cancer cells.

14 Mar 2013

Researchers discover likely origin of epithelial ovarian cancer

Cornell University researchers have discovered a likely origin of epithelial ovarian cancer (ovarian carcinoma), the fifth leading cause of cancer death among women in the United States.

7 Mar 2013

Scientists succeed in direct observation of microorganisms feeding on the intestinal mucosa

The microbiology team of David Berry, Alexander Loy and Michael Wagner from the Faculty of Life Sciences, in collaboration with scientists at the Max F. Perutz Laboratories and with the help of NanoSIMS technology, has for the first time succeeded in directly observing microorganisms feeding on the intestinal mucosa.

6 Mar 2013

Insight into cellular operations that give extraordinary staying power to S. mansoni

From the point of view of its ultimate (human) host, the parasitic flatworm Schistosoma mansoni has a gruesome way of life. It hatches in feces-tainted water, grows into a larva in the body of a snail and then burrows through human skin to take up residence in the veins. Once there, it grows into an adult, mates and, if it's female, starts laying eggs. It can remain in the body for decades.

26 Feb 2013

Schistosome stem cells could explain how the worms survive for so many years

The parasites that cause schistosomiasis, one of the most common parasitic infections in the world, are notoriously long-lived. Researchers have now found stem cells inside the parasite that can regenerate worn-down organs, which may help explain how they can live for years or even decades inside their host.

24 Feb 2013

Blaze Bioscience completes $8.5 million Series A financing

Blaze Bioscience, Inc., a biotechnology company dedicated to developing innovative products to improve the lives of cancer patients, today announced the completion of a Series A financing totaling $8.5 million and bringing the total funds raised since inception to $9.8 million.

22 Feb 2013

USP evaluates Raman device's potential to detect counterfeit and substandard medicines

With substandard and counterfeit medicines a dangerous and growing problem in the developing world and elsewhere, identifying new technologies to detect such drugs is an urgent matter. In a new study published in the Journal of Pharmaceutical and Biomedical Analysis, scientists from the U.S. Pharmacopeial Convention (USP) evaluated a handheld Raman device's potential to detect counterfeit and substandard medicines.

21 Feb 2013

Liposomes not capable of transporting themselves deep into the skin

Liposomes are small fat capsules, often added to beauty products. According to the beauty industry liposomes are capable of transporting active ingredients deep into the skin and release the active ingredients so that they can alter the skin-s structure by rejuvenating and smoothing the skin.

20 Feb 2013

Scientists demonstrate advantages of wavelength-modulated Raman spectroscopy

Raman spectroscopy has enabled incredible advances in numerous scientific fields and is a powerful tool for tissue classification and disease recognition, although there have been considerable challenges to using the method in a clinical setting. Scientists have now demonstrated the advantages of wavelength-modulated Raman spectroscopy, opening the door to wider biomedical and clinical applications such as real-time assessment of tissues during surgery.

20 Feb 2013

Tiny microscope can help scientists observe neuronal firings in the brain

If you want to read a mouse's mind, it takes some fluorescent protein and a tiny microscope implanted in the rodent's head.

20 Feb 2013

Researchers create new ultra-sensitive tool for chemical, DNA and protein analysis

Utilizing optical characteristics first demonstrated by the ancient Romans, researchers at the University of Illinois at Urbana-Champaign have created a novel, ultra-sensitive tool for chemical, DNA, and protein analysis.

16 Feb 2013

Improving tuberculosis (TB) diagnosis: an interview with Professor Madhukar Pai, MD, PhD

TB is an infectious disease caused by Mycobacterium tuberculosis. Nearly 9 million people develop TB every year, and TB kills nearly 1.4 million individuals each year. While the incidence of TB has steadily declined in the west, it remains a huge public health problem in many developing countries, with India having the highest burden.

15 Feb 2013

TP PCR methodology may help streamline genetic testing for Huntington's

A new test may help to streamline genetic testing for Huntington Disease (HD) by generating accurate results, avoiding unnecessary additional testing, and improving turnaround time.

14 Feb 2013

Ability to tune gene activity will permit refined research for drug resistance, cancer

Scientists who built a synthetic gene circuit that allowed for the precise tuning of a gene's expression in yeast have now refined this new research tool to work in human cells, according to research published online in Nature Communications.

13 Feb 2013

Berkeley Lab researchers resolve EGFR activation mystery

Researchers with Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have provided important new details into the activation of the epidermal growth factor receptor (EGFR), a cell surface protein that has been strongly linked to a large number of cancers and is a major target of cancer therapies.

12 Feb 2013

Overexpression of alpha-synuclein can cause Parkinson's

Researchers at the University of California, San Diego School of Medicine say overexpression of a protein called alpha-synuclein appears to disrupt vital recycling processes in neurons, starting with the terminal extensions of neurons and working its way back to the cells' center, with the potential consequence of progressive degeneration and eventual cell death.

10 Feb 2013

More than £6M funding awarded to enhance development of biopharmaceuticals

More than £6M of funding has been awarded to enhance the development of biopharmaceuticals. In total £6.5M will fund 12 projects to deliver commercially important results, such as industrial-scale production of antibodies, stem cell preservation at room temperature, biopharmaceutical production using microbes and commercial scale stem cell therapy.

6 Feb 2013

An Introduction to the LV200 Bioluminescence Microscope

News-Medical speaks to Robert Schmalzigaug to explore the field of bioluminescence imaging and the applications of the LV200 microscope.

From Evident Corporation - Life Sciences 5 Feb 2013

Study shows how placental circulation can influence malarial parasite behavior and infection

Malaria in pregnancy causes a range of adverse effects, including abortions, stillbirths, premature delivery and low infant birth weight. Many of these effects are thought to derive from a placental inflammatory response resulting from interaction of infected red blood cells with the placental tissue.

3 Feb 2013

Fluorescence News and Research

Researchers develop single molecule test for detecting methylated DNA

UNM scientists identify chemical compound that appears to control cell metastases

Researchers discover likely origin of epithelial ovarian cancer

Scientists succeed in direct observation of microorganisms feeding on the intestinal mucosa

Insight into cellular operations that give extraordinary staying power to S. mansoni

Schistosome stem cells could explain how the worms survive for so many years

Blaze Bioscience completes $8.5 million Series A financing

USP evaluates Raman device's potential to detect counterfeit and substandard medicines

Liposomes not capable of transporting themselves deep into the skin

Scientists demonstrate advantages of wavelength-modulated Raman spectroscopy

Tiny microscope can help scientists observe neuronal firings in the brain

Researchers create new ultra-sensitive tool for chemical, DNA and protein analysis

Improving tuberculosis (TB) diagnosis: an interview with Professor Madhukar Pai, MD, PhD

TP PCR methodology may help streamline genetic testing for Huntington's

Ability to tune gene activity will permit refined research for drug resistance, cancer

Berkeley Lab researchers resolve EGFR activation mystery

Overexpression of alpha-synuclein can cause Parkinson's

More than £6M funding awarded to enhance development of biopharmaceuticals

An Introduction to the LV200 Bioluminescence Microscope

Study shows how placental circulation can influence malarial parasite behavior and infection

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