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Science’s Breakthrough of the Year: GLP-1 agonists can blunt obesity-associated health problems

Science has named the development of glucagon like peptide-1 (GLP-1) agonists and this year's discovery that these drugs can blunt obesity-associated health problems as its 2023 Breakthrough of The Year.

15 Dec 2023

Navigating STXBP1-related disorders: Unraveling clinical and developmental outcomes

Researchers examined the combined patient-years of seizure and developmental histories in individuals with disorders related to the STXBP1 gene.

4 Dec 2023

Researchers develop a new early alert model for pandemic predictions in Germany

An early alert indicator and trend forecasting model for pandemic situations in Germany.

29 Nov 2023

Obesity linked to prostate cancer risk: New study uncovers inherited dangers from fathers

Obesity contributes to prostate cancer risk and can be inherited from obese fathers, as shown in a review of over 280 studies examining obesity's impact on carcinogenesis and heritability.

23 Nov 2023

Study suggests non-prescription sales data can help to forecast respiratory disease fatalities

Researchers investigated the value of integrating sales of non-prescription medications (e.g., cough syrups) for improved forecasting of deaths from respiratory diseases in England using artificial intelligence (AI)-based predictive tools.

23 Nov 2023

Sales of respiratory medications key to predicting disease mortality, UK study finds

The value of integrating national longitudinal shopping data into respiratory disease forecasting models.

22 Nov 2023

AI-enhanced autism therapy: How multi-stage ensemble learning is changing the game By Pooja

Anticipating and identifying characteristics that impact or contribute to autism spectrum disorder therapy.

17 Nov 2023

AI shows promise in predicting type 2 diabetes but faces hurdles for clinical use

Researchers have conducted a comprehensive review of AI-based models for predicting type 2 diabetes, revealing their potential for individualized risk assessment and preventative care. Despite promising results, the study calls for more extensive validation and collaboration between AI and medical experts for effective clinical application.

26 Oct 2023

Deep-learning models predict COVID-19 cases globally with high accuracy

An AI deep learning model to predict the number of COVID-19 cases 14 days into the future.

24 Oct 2023

EVScape: New tool to forecast which SARS-CoV-2 variants could dodge our immunity

Researchers have developed EVScape, a predictive tool that identifies which SARS-CoV-2 strains are most likely to evade host immunity. Utilizing a deep generative model and structural information, the tool offers early warning about viral variants, aiding in the timely development of effective vaccines and treatments.

12 Oct 2023

New report forecasts growing health and economic impacts from stroke between 2020 and 2050

Unless urgent action is taken, the number of people who die from stroke globally is estimated to increase by 50% by 2050 to 9.7 million deaths per year, with annual costs as high as US$2.3 trillion possible, according to a new report on pragmatic solutions to reduce the global burden of stroke: a World Stroke Organization–Lancet Neurology Commission.

9 Oct 2023

Machine learning-based models can predict diabetes incidence across several ethnicities

Predicting diabetes mellitus type 2 (T2D) incidence and prevalence across differing ethnicities.

27 Sep 2023

New study maps the spread of brain changes in psychosis

Psychoses like schizophrenia cost billions of dollars annually and derail the lives of people struggling with the disease.

20 Sep 2023

U-M receives CDC grant to establish new center to improve public health response to disease outbreaks

The University of Michigan is among 13 institutions that will receive funding from the Centers for Disease Control and Prevention to be part of a national network of centers focused on predicting and responding to future disease outbreaks.

20 Sep 2023

CDC awards $17.5M to UC San Diego-led coalition to develop innovative outbreak response tools

The Centers for Disease Control and Prevention (CDC) has awarded $17.5 million to a coalition led by researchers at UC San Diego to develop innovative tools and networks to respond rapidly to emerging disease outbreaks.

19 Sep 2023

The growing role of AI in science and discovery

With the advent of ChatGPT4, the use of artificial intelligence in medicine has absorbed the public's attention, dominated news headlines, and sparked vigorous debates about the promise and peril of medical AI.

21 Aug 2023

FDA approved Rexulti to be the first antipsychotic for treating agitation in elderly patients with dementia

In trials, the antipsychotic drug brexpiprazole (Rexulti) failed to provide a clinically meaningful benefit and increased the risk of death. Yet the US Food and Drug Administration (FDA) has fast tracked its approval, making Rexulti the first antipsychotic for treating agitation in elderly patients with dementia.

18 Aug 2023

Databases, techniques for variant forecasting and early warning of emerging infectious diseases

The coronavirus disease 2019 (COVID-19) pandemic has dramatically increased the awareness of emerging infectious diseases.

17 Aug 2023

Study explores the use of collective intelligence to improve medical diagnosis

A recent study revealed the possibility of combining knowledge representation models and collective intelligence for medical diagnosis.