Ganglion News and Research

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In anatomy, a ganglion (plural ''ganglia'') is a biological tissue mass, most commonly a mass of nerve cell bodies. Cells found in a ganglion are called ganglion cells, though this term is also sometimes used to refer specifically to retinal ganglion cells.

Retinal measurements associated with Parkinson’s disease duration

The inner retinal layers in the eyes of patients with Parkinson’s disease are thinner than those of healthy people’s eyes, except for the inner nuclear layer, which is thicker, show the results of a prospective study involving the latest optical coherence tomography methods.

1 May 2014

Researchers identify possible mechanism for re-growing damaged nerve fibres in central nervous system

A new discovery suggests it could one day be possible to chemically reprogram and repair damaged nerves after spinal cord injury or brain trauma.

1 Apr 2014

Photoreactive compounds open new routes to treatment of neurological diseases

Photoreactive compounds developed by scientists of Ludwig-Maximilians-Universitaet (LMU) in Munich directly modulate nerve-cell function, and open new routes to the treatment of neurological diseases, including chronic pain and certain types of visual impairment.

3 Mar 2014

Newly developed compound may allow blind see light

Progressive degeneration of photoreceptors-the rods and cones of the eyes-causes blinding diseases such as retinitis pigmentosa and age-related macular degeneration. While there are currently no available treatments to reverse this degeneration, a newly developed compound allows other cells in the eye to act like photoreceptors. As described in a study appearing in the February 19 issue of the Cell Press journal Neuron, the compound may be a potential drug candidate for treating patients suffering from degenerative retinal disorders.

20 Feb 2014

Randomized trial shows injecting anesthetic near nerve bundle reduces troublesome hot flashes

Injecting a little anesthetic near a nerve bundle in the neck cut troublesome hot flashes significantly, shows a new randomized, controlled trial published online today in Menopause, the journal of The North American Menopause Society (NAMS).

5 Feb 2014

Study shows endoplasmic reticulum stress plays important role in diabetic retinopathy

Endoplasmic reticulum stress is closely involved in the early stage of diabetic retinopathy. According a study published in the Neural Regeneration Research (Vol. 8, No. 33, 2013), endoplasmic reticulum stress played an important role in the hyperglycemia-induced death of ganglion cells and impairment of retinal microvessels.

5 Jan 2014

Melatonin plays major role in pain transmission

Accumulating research indicates that melatonin has a major role in pain transmission and has an ultra-sensitizing effect. Dr. Fang Huang and colleagues from Sun Yat-sen University in China for the first time located the distribution of melatonin receptor 1 in the caudal spinal trigeminal nucleus.

31 Dec 2013

Research: Neuropeptides may serve as index for evaluating early peripheral nerve injury

Substance P and calcitonin gene-related peptide are the main neuropeptides in peripheral nerve ganglia, which can anterogradely transmit nociceptive information to the central nervous system.

27 Dec 2013

Transient receptor potential channel A1 causes calcitonin gene-related peptide release in neurons

Transient receptor potential channel A1 is one of the important transducers of noxious stimuli in the primary afferents, which may contribute to generation of neurogenic inflammation and hyperalgesia.

26 Dec 2013

Adding corticosteroid fluocortolone with standard therapy improves visual acuity in NAION patients

Nonarteritic anterior ischemic optic neuropathy is one of the leading causes of sudden and irreversible loss of vision in older adults. In a prospective randomized trial of 60 patients with NAION, investigators have shown that the addition of the corticosteroid fluocortolone to standard therapy significantly improves both short- and long-term visual acuity, especially when given soon after the onset of symptoms. Their results are published in Restorative Neurology and Neuroscience.

20 Nov 2013

Researchers study link between vision loss and Alzheimer's disease

An international team of researchers studying the link between vision loss and Alzheimer's disease report that the loss of a particular layer of retinal cells not previously investigated may reveal the disease's presence and provide a new way to track disease progression.

14 Nov 2013

Cellectricon introduces Dynaflow Resolve Temperature Control system for ion channel research

Cellectricon, a leading provider of advanced cell-based screening technologies and services, launches the Dynaflow Resolve Temperature Control system at Neuroscience 2013 (San Diego), booth #933.

From Cellectricon 12 Nov 2013

Oligomeric proanthocyanidin has protective effect on retinal ganglion cells, shows study

The death of retinal ganglion cells is a hallmark of many optic neurodegenerative diseases such as glaucoma and retinopathy. Oxidative stress is one of the major reasons to cause the cell death.

4 Nov 2013

Cellectricon to demonstrate Cellaxess technology at Neuroscience 2013

Cellectricon, a leading provider of advanced cell-based screening technologies and services, will be presenting new data at Neuroscience 2013, 9-13 November, San Diego (USA).

From Cellectricon 31 Oct 2013

Study: Light enhances brain activity during cognitive task even in blind people

Light enhances brain activity during a cognitive task even in some people who are totally blind, according to a study conducted by researchers at the University of Montreal and Boston's Brigham and Women's Hospital.

29 Oct 2013

Non-hormonal chronic pain treatment reduces moderate-to-severe hot flashes

Menopausal women suffer from half as many hot flashes after receiving a non-hormonal chronic pain treatment, according to a study presented at the ANESTHESIOLOGY 2013 annual meeting.

14 Oct 2013

Wiring diagram of retinal neurons: The first step toward mapping the human brain

The human brain has 100 billion neurons, connected to each other in networks that allow us to interpret the world around us, plan for the future, and control our actions and movements. MIT neuroscientist Sebastian Seung wants to map those networks, creating a wiring diagram of the brain that could help scientists learn how we each become our unique selves.

8 Aug 2013

Duke Medicine researchers identify a protein critical to TMJD pain

Temporomandibular joint disorder (TMJD) is the most common form of oral or facial pain, affecting over 10 million Americans. The chronic disorder can cause severe pain often associated with chewing or biting down, and lacks effective treatments.

2 Aug 2013

Cochlear implants restore usable hearing to deaf patients

Cochlear implants, electrical prosthetic devices that stimulate inner ear neurons of individuals who have lost their cochlear sensory cells, restore usable hearing to deaf patients. Cochlear implant electrodes are placed in the fluid-filled scala tympani of the cochlea, at a significant distance from the spiral ganglion and even from the spiral ganglion dendrites.

22 Jul 2013

NACC recommendations address established pain therapies and preview potential future advances

Recommendations of the Neuromodulation Appropriateness Consensus Committee (NACC), announced at the 11th World Congress of the International Neuromodulation Society (INS), address established therapies and preview emerging and potential future advances.

13 Jun 2013