Gastroenterology News and Research

RSS

Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

Tibotec submits MAA for investigational HIV drug TMC278 to European Medicines Agency

Tibotec Pharmaceuticals today announced its submission of a Marketing Authorisation Application (MAA) to the European Medicines Agency (EMA) for TMC278 (rilpivirine, as hydrochloride), an investigational non-nucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of HIV. The proposed indication would make TMC278 available for once-daily use with other antiretroviral agents in treatment-naive HIV-1-infected adults.

3 Sep 2010

Orexigen and Takeda partner to develop, commercialize Contrave in US, Canada and Mexico

Orexigen® Therapeutics, Inc. and Takeda Pharmaceutical Company Limited, today announced that they have entered into an exclusive partnership to develop and commercialize Contrave® (naltrexone SR/bupropion SR), Orexigen's investigational drug for the treatment of obesity, in the United States, Canada and Mexico.

2 Sep 2010

Researchers dispute study findings that show greater incidence of surgery for children with CD

A new multi-center study of 854 children with Crohn's disease shows a 5-year cumulative risk of bowel surgery is significantly lower than reported in recent studies. The findings of the study, led by Hasbro Children's Hospital, also indicate that children diagnosed between ages 13 and 16 had an increased risk of bowel surgery, and that a common treatment that begins at diagnosis, immunomodulator therapy, did not alter the risk of surgery.

2 Sep 2010

GI Dynamics, Elemental Healthcare sign agreement for distribution of EndoBarrier Gastrointestinal Liner

GI Dynamics, a leader in non-surgical, endoscopic treatments for type 2 diabetes and obesity, today announced it has entered into a new agreement with Elemental Healthcare, based in Hungerford, Berkshire, for the distribution of the EndoBarrier Gastrointestinal Liner in England, Wales, Scotland, Northern Ireland and Ireland.

2 Sep 2010

USFDA grants Sun Pharma subsidiary approval for generic Strattera capsules ANDA

Sun Pharmaceutical Industries Ltd. announced that USFDA has granted its subsidiary an approval for its Abbreviated New Drug Application (ANDA) to market a generic version of Strattera ®, atomoxetine hydrochloride capsules.

2 Sep 2010

Tooth brush in a teenager’s stomach

A 15-year-old girl in New Zealand came to the emergency department at an Auckland hospital after accidentally swallowing her 19-centimetre toothbrush. The case study was published in the New Zealand Medical Journal.

31 Aug 2010

Study: IV ibuprofen decreases pain, morphine use in pre and post-operative orthopedic surgery patients

Cumberland Pharmaceuticals Inc. today announced the publication of new data supporting the safety and efficacy of Caldolor® (ibuprofen) Injection in pre and post-operative orthopedic surgery patients. The study, which was published in the August edition of the peer-reviewed journal Pain Medicine, concludes that IV ibuprofen significantly decreased pain and morphine use when compared with placebo.

31 Aug 2010

Ipsen 2010 first half revenue increases to €31.7 million

The Board of Directors of Ipsen, chaired by Jean-Luc Bélingard, met on August 30, 2010 to review the Group's results for the first half 2010, published today

31 Aug 2010

Salix Pharmaceuticals to settle patent litigation of Novel's generic version of MOVIPREP

Salix Pharmaceuticals, Ltd. today announced that Salix and Norgine B. V. have entered into an agreement with Novel Laboratories, Inc. to settle patent litigation currently pending in the U.S. District Court for the District of New Jersey (Civil Action No. 3:08-02311 (FLW)(TJB)) regarding Novel's proposed generic version of MOVIPREP.

31 Aug 2010

Meda signs agreement to acquire Alaven

Meda has signed an agreement to acquire the US specialty pharmaceutical company Alaven. The acquisition will significantly enhance Meda's marketing capabilities in the US and expand the therapeutic focus to include both gastroenterology and women's health; areas that Meda already operates in outside of the US.

30 Aug 2010

EndoGastric Solutions receives Series F financing to support Natural Orifice Surgery marketplace

EndoGastric Solutions (EGS), the recognized leader in the emerging field of Natural Orifice Surgery (NOS), today announced that Canaan Partners and Radius Ventures co-led a $30 Million Series F financing designed to support the company through profitability.

30 Aug 2010

Practice guideline-recommended care reduces bleeding in cirrhosis patients

Compliance with practice guideline-recommended treatment for cirrhosis is associated with a reduction in first esophageal variceal hemorrhage (EVH; bleeding), according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association Institute.

26 Aug 2010

Warner Chilcott receives FDA response to citizen petition for ASACOL and ASACOL HD products

Warner Chilcott plc today announced that it has received the Food and Drug Administration's response to a citizen petition it had filed regarding its ASACOL and ASACOL HD products.

25 Aug 2010

Tranzyme Pharma to present ulimorelin Phase 2 data at NGM Meeting

Tranzyme Pharma announced today that John Wo, MD, Professor of Medicine, Director, Clinical Research, Division of Gastroenterology, Hepatology and Nutrition, University of Louisville, Louisville, KY, will present ulimorelin Phase 2 data at this year's Joint International NGM Meeting on Saturday, August 28, 2010.

25 Aug 2010

Warner Chilcott adds $1.5 billion for senior secured credit facilities

Warner Chilcott plc today announced that it has completed an amendment to its existing senior secured credit facilities, pursuant to which it has incurred an additional $1.5 billion aggregate principal amount of new term loans

21 Aug 2010

FDA extends review on Acetadote for non-acetaminophen acute liver failure

Cumberland Pharmaceuticals Inc. today announced the U.S. Food and Drug Administration (FDA) has extended its review of the supplemental new drug application (sNDA) for the use of Acetadote® (acetylcysteine) Injection in patients with non-acetaminophen acute liver failure.

21 Aug 2010

Trial shows positive results for radioembolisation technique for colorectal cancer liver metastases treatment

Using the innovative technique of radioembolisation to treat patients with inoperable colorectal cancer liver metastases who have failed all standard-of-care chemotherapy options can more than double the time until their disease progresses, according to the final results of a Phase III randomised controlled trial published in the prestigious Journal of Clinical Oncology.

20 Aug 2010

Research on gut mucosa enables effective drug treatment for irritable bowel syndrome

Irritable bowel syndrome makes life miserable for those affected an estimated ten percent or more of the population. And what irritates many of them even more is that they often are labeled as hypochondriacs, since physical causes for irritable bowel syndrome have never been identified. Now, biologists at the Technische Universitaet Muenchen (TUM) have shed new light on the matter: They have discovered mini-inflammations in the mucosa of the gut, which upset the sensitive balance of the bowel and are accompanied by sensitization of the enteric nervous system.

20 Aug 2010

Elephant Capital and ClinTec International announce partnership deal

ClinTec International, a global Clinical Research Organisation ("CRO") announces financial and strategic partnership with Elephant Capital plc., a London AIM market listed private equity firm. With an investment of £8 Million GBP, Elephant has acquired a significant minority stake in ClinTec.

19 Aug 2010

USFDA approves Sun Pharma's generic Venlafaxine Hydrochloride Extended Release tablets ANDA

Sun Pharma announced that USFDA has granted an approval for an Abbreviated New Drug Application (ANDA) to market a generic version of Venlafaxine Hydrochloride Extended Release tablets.

19 Aug 2010

Gastroenterology News and Research

Further Reading

Tibotec submits MAA for investigational HIV drug TMC278 to European Medicines Agency

Orexigen and Takeda partner to develop, commercialize Contrave in US, Canada and Mexico

Researchers dispute study findings that show greater incidence of surgery for children with CD

GI Dynamics, Elemental Healthcare sign agreement for distribution of EndoBarrier Gastrointestinal Liner

USFDA grants Sun Pharma subsidiary approval for generic Strattera capsules ANDA

Tooth brush in a teenager’s stomach

Study: IV ibuprofen decreases pain, morphine use in pre and post-operative orthopedic surgery patients

Ipsen 2010 first half revenue increases to €31.7 million

Salix Pharmaceuticals to settle patent litigation of Novel's generic version of MOVIPREP

Meda signs agreement to acquire Alaven

EndoGastric Solutions receives Series F financing to support Natural Orifice Surgery marketplace

Practice guideline-recommended care reduces bleeding in cirrhosis patients

Warner Chilcott receives FDA response to citizen petition for ASACOL and ASACOL HD products

Tranzyme Pharma to present ulimorelin Phase 2 data at NGM Meeting

Warner Chilcott adds $1.5 billion for senior secured credit facilities

FDA extends review on Acetadote for non-acetaminophen acute liver failure

Trial shows positive results for radioembolisation technique for colorectal cancer liver metastases treatment

Research on gut mucosa enables effective drug treatment for irritable bowel syndrome

Elephant Capital and ClinTec International announce partnership deal

USFDA approves Sun Pharma's generic Venlafaxine Hydrochloride Extended Release tablets ANDA

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News