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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.
Simvastatin hinders positive effects of exercise for obese adults, say researchers

Simvastatin hinders positive effects of exercise for obese adults, say researchers

Statins, the most widely prescribed drugs worldwide, are often suggested to lower cholesterol and prevent heart disease in individuals with obesity, diabetes and metabolic syndrome, which is a combination of medical disorders including excess body fat and/or high levels of blood pressure, blood sugar and/or cholesterol. [More]

Changes in specific proteins contribute to 'leaky-gut' wall

Scientists at Trinity College Dublin have made an important advance in understanding the biological factors that keep the lining of the gut wall intact. Associate Professor, Maria O'Sullivan at Trinity's School of Medicine and St James's Hospital and colleagues, showed that changes in specific proteins may contribute to a 'leaky-gut' wall which may have important implications for common chronic digestive diseases such as irritable bowel syndrome and inflammatory bowel disease. [More]

PENTAX Medical releases EPK-i5010 Video Processor with PENTAX i-SCAN

PENTAX Medical Company, a healthcare industry leader in endoscopic imaging, announces the U.S. launch of the EPK-i5010 Video Processor with PENTAX i-SCAN™, the industry's highest resolution HD+ imaging technology for flexible endoscopy. [More]
Simponi injection gets FDA approval to treat adults with ulcerative colitis

Simponi injection gets FDA approval to treat adults with ulcerative colitis

The U.S. Food and Drug Administration today approved a new use for Simponi (golimumab) injection to treat adults with moderate to severe ulcerative colitis. [More]

Industry's highest resolution HD+ imaging technology for flexible endoscopy launched by PENTAX Medical

PENTAX Medical Company, a healthcare industry leader in endoscopic imaging, announces the U.S. launch of the EPK-i®5010 Video Processor with PENTAX i-SCAN™, the industry's highest* resolution HD+ imaging technology for flexible endoscopy. [More]

AGA Research Foundation receives grant for gastroenterology research

Today, the American Gastroenterological Association announced that Takeda Pharmaceuticals U.S.A., Inc. will provide a $1.5 million unrestricted grant to the AGA Research Foundation endowment. [More]
Synageva BioPharma reports study results of sebelipase alfa in adults with late onset LAL Deficiency

Synageva BioPharma reports study results of sebelipase alfa in adults with late onset LAL Deficiency

Synageva BioPharma Corp., a biopharmaceutical company developing therapeutic products for rare diseases, today reported 12-month results from an ongoing extension study with sebelipase alfa in adults with late onset Lysosomal Acid Lipase Deficiency. [More]
Special issue of Gastroenterology presents variety of topics related to pancreas

Special issue of Gastroenterology presents variety of topics related to pancreas

The editors of Gastroenterology, the official journal of the American Gastroenterological Association Institute, are pleased to announce the publication of this year's highly anticipated special 13th issue. [More]

UA researchers discover genetic mutations that cause severe epilepsies in children

Researchers at the University of Arizona have successfully determined the genetic mutations causing severe epilepsies in seven out of 10 children for whom the cause of the disorder could not be determined clinically or by conventional genetic testing. [More]
Breast milk might prevent premature babies from deadly intestinal condition

Breast milk might prevent premature babies from deadly intestinal condition

An ingredient that naturally occurs in breast milk might be used to prevent premature babies from developing a deadly intestinal condition that currently is largely incurable, according to researchers at the University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of UPMC in this week's online early edition of the Proceedings of the National Academy of Sciences. [More]

Cleveland Clinic receives $2M for research in colorectal surgery

Kenneth M. Garschina and his wife, Sara Story, have pledged $2 million to Cleveland Clinic's Digestive Disease Institute to create an endowed chair for research in colorectal surgery. The donation coincides with the re-dedication of two previously funded endowed chairs. [More]
Sedasys gets PMA approval from FDA for SEDASYS System

Sedasys gets PMA approval from FDA for SEDASYS System

Sedasys, a Division of Ethicon Endo-Surgery, Inc., today announced that the U.S. Food and Drug Administration has granted PMA approval for the SEDASYS System, the first computer-assisted personalized sedation system. [More]
Aclidinium and formoterol combination demonstrates significant lung function improvement in the second pivotal efficacy trial

Aclidinium and formoterol combination demonstrates significant lung function improvement in the second pivotal efficacy trial

Almirall, S.A. (ALM:MC) and Forest Laboratories, Inc. (NYSE:FRX) today announced positive topline results from AUGMENT/COPD, the second six-month pivotal phase III clinical trial evaluating the efficacy and safety of investigational fixed dose combinations of aclidinium bromide (LAMA) and formoterol fumarate (LABA) for the treatment of Chronic Obstructive Pulmonary Disease (COPD), delivered in the Pressair™ inhaler (Genuair® outside the USA). [More]
Forest Laboratories, Almirall report positive topline results from AUGMENT COPD

Forest Laboratories, Almirall report positive topline results from AUGMENT COPD

Forest Laboratories, Inc. and Almirall, S.A. today announced positive topline results from AUGMENT COPD, the second six-month pivotal phase III clinical trial evaluating the efficacy and safety of investigational fixed dose combinations of aclidinium bromide and formoterol fumarate, delivered in the Pressair (Genuair outside the USA) inhaler. [More]

Study: Biologic response modifying drugs can cause acute liver injury

A commonly used class of biologic response modifying drugs can cause acute liver injury with elevated liver enzymes, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association. [More]
Exclusion diet boosts anal fissure healing

Exclusion diet boosts anal fissure healing

Research published in the American Journal of Gastroenterology shows that an exclusion diet combined with medical treatment can increase healing rates in patients with chronic anal fissure who have been referred for surgery. [More]
Intermediate anti-tTG levels affects birth outcomes, new study reveals

Intermediate anti-tTG levels affects birth outcomes, new study reveals

Pregnant women with mid to high levels of antibodies common in patients with celiac disease are at risk for having babies with reduced fetal weight and birth weight, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. [More]

Dental problems create substantial burden

Over 40 million hours are lost each year due to dental problems and their treatment in the Canadian population, study findings indicate. [More]
GS-9620 therapy suppresses hepatitis B virus infection

GS-9620 therapy suppresses hepatitis B virus infection

A novel drug developed by Gilead Sciences and tested in an animal model at the Texas Biomedical Research Institute in San Antonio suppresses hepatitis B virus infection by stimulating the immune system and inducing loss of infected cells. [More]

New clinical algorithm to treat complex pediatric patients with ARPKD

A collaborative team of physician-scientists at the Medical College of Wisconsin and Children's Hospital of Wisconsin Research Institute has developed a new evidence-based, clinical algorithm to help physicians treat complex patients with autosomal recessive polycystic kidney disease. [More]