Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

Study highlights need to improve screening and surveillance for Barrett's esophagus

A new study published in Gastroenterology aims to improve the effectiveness of screening and surveillance practices for early cancer detection in Barrett's esophagus (BE).

20 Jul 2023

Proteins CEACAM1 and TIM-3 may help protect liver transplants

A new study identifies how certain proteins in the immune system interact leading to organ rejection. The study, which involved experiments on mice and human patients, uncovered an important communication pathway between two molecules called CEACAM1 (CC1) and TIM-3, finding that the pathway plays a crucial role in controlling the body's immune response during liver transplantation.

19 Jul 2023

Opioid addiction linked to neural differences in response to drug cues

An Icahn School of Medicine at Mount Sinai study sheds new light on some of the underlying neurobiological mechanisms of opioid addiction, which accounted for three-quarters of the more than 100,000 fatal drug overdoses in the United States in 2021.

18 Jul 2023

Study shines light on genetic differences among children with rare neurodevelopmental condition

New research led by the Seaver Autism Center for Research and Treatment at Mount Sinai has illuminated genetic differences among children with a rare neurodevelopmental condition and could point the way toward a precision medicine approach to caring for these children.

17 Jul 2023

New method improves prediction of liver disease progression

A research team from the Department of Medicine III at MedUni Vienna and University Hospital Vienna has conducted a large-scale study showing the important value of repeated liver assessments by a novel method that can significantly improve risk assessment in patients with chronic liver disease.

17 Jul 2023

Mount Sinai's new cardiac catheterization lab brings life-saving care to western Queens

Mount Sinai Queens today announced the opening of a new cardiac catheterization lab that will provide rapid and comprehensive care to hundreds of heart patients every year for life-threatening emergencies and scheduled cardiac procedures.

11 Jul 2023

Lilly granted MHRA marketing authorization in Great Britain for a ground-breaking UC therapy

Eli Lilly and Company announced today that the Medicines and Healthcare products Regulatory Agency (MHRA) has granted marketing authorisation (MA) for mirikizumab (OMVOH®) for the treatment of adult patients with moderately to severely active ulcerative colitis who have had an inadequate response with, lost response to, or were intolerant to either conventional therapy or a biologic treatment.

10 Jul 2023

Swarm learning shows promise in cancer research

The DECADE research project is the first to use swarm learning in cancer research. The German Cancer Aid is funding the joint project of several university hospitals with around 1.5 million euros.

6 Jul 2023

Study identifies role of ROR1 in pancreatic cancer metastasis

Tumor-initiating cells, or cancer stem cells, are gaining attention in cancer therapy, as they can travel through the body and cause cancerous tumors at other sites through metastasis.

5 Jul 2023

New drug effective as a treatment against ulcerative colitis, clinical trial shows

A new drug, investigated by Amsterdam UMC together with colleagues around the world, is effective as a treatment against ulcerative colitis.

28 Jun 2023

Seven risk factors for early onset colorectal cancer in males identified

Colorectal cancer incidence and deaths are declining for individuals age 50 and older, but are increasing for those under 50.

27 Jun 2023

Researchers identify a potential new drug for NASH-related fibrosis

Researchers at the University of California San Diego School of Medicine have led a study to examine a potential new treatment option for patients with nonalcoholic steatohepatitis (NASH)-related fibrosis.

26 Jun 2023

Plant-based foods may be a key to preventing childhood obesity

A new study led by researchers from the Mass General Brigham healthcare system suggests that taking a "food is medicine" approach could increase nutrition security for families and lead to reductions in body mass index (BMI) in children.

22 Jun 2023

Gestational diabetes influences diabetes risk and blood sugar control

People who develop diabetes following pregnancy were significantly less likely to be able to bring it under control if they had experienced gestational diabetes during their pregnancy, especially if they were Black or Hispanic, according to a Mount Sinai study published on June 21 in the journal Diabetes Care.

21 Jun 2023

$3.3M HHS grant supports UTHealth Houston study on combination treatment strategy for pancreatic cancer

A combination strategy of endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) with chemotherapy for pancreatic cancer will be studied at UTHealth Houston through a $3.3 million grant from the National Cancer Institute by the U.S. Department of Health and Human Services.

20 Jun 2023

Broader search needed for successful management of eosinophilic gastritis

The good news: a monoclonal antibody treatment called benralizumab proved quite effective in a clinical trial at depleting the number of eosinophils found in the blood and digestive tract tissues of patients with eosinophilic gastritis.

16 Jun 2023

$1.9 million grant awarded to explore the effect of antifungal drugs in Crohn's patients

Dr. Iliyan D. Iliev, an associate professor of immunology in medicine in the Division of Gastroenterology and Hepatology, co-director of the Microbiome Core and a member of the Jill Roberts Institute for Research in Inflammatory Bowel Disease (IBD) at Weill Cornell Medicine, is the lead investigator on a grant to Weill Cornell Medicine from The Leona M. and Harry B. Helmsley Charitable Trust to target pathogenic fungi in patients with Crohn's disease.

15 Jun 2023

DIALIVE device may be a disease-modifying therapy for patients with acute-on-chronic liver failure

Acute-on-chronic liver failure (ACLF) occurs in 30% of hospitalized cirrhosis patients, leading to over one million deaths worldwide each year.

31 May 2023

Tumors in distant organs remotely reprogram the liver

Cancers often release molecules into the bloodstream that pathologically alter the liver, shifting it to an inflammatory state, causing fat buildup and impairing its normal detoxifying functions, according to a study from investigators at Weill Cornell Medicine.

25 May 2023

Study sheds light on global disparities in mortality rates from liver disease

New research is shedding light on global disparities in mortality rates from late-stage liver disease, also called cirrhosis.