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Study reveals accelerated progression of Alzheimer's in people with Down syndrome

Nearly all adults with Down syndrome will develop evidence of Alzheimer's disease by late middle age.

16 Apr 2024

Study reveals molecular changes in brain cells with Lewy bodies

A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias.

16 Apr 2024

Study reveals novel approach to promote efficient uptake of ASOs into cancer cells

Antisense oligonucleotides (ASOs) are next-generation drugs that can treat disease by blocking the transfer of harmful messages from our genes.

16 Apr 2024

Study reveals human gut plasmid with biomarker potential

A component of the human intestinal flora that has been little studied to date is the focus of a new study.

16 Apr 2024

Placental IGFBP1: A key factor in development of gestational diabetes

A new study led by the Harvard Pilgrim Health Care Institute has identified that a deficit in the placental expression of the gene insulin-like growth factor 1 (IGFBP1) and low IGFBP1 circulating levels are associated with insulin resistance during pregnancy, highlighting a potential risk factor for the development of gestational diabetes.

16 Apr 2024

Pitt researchers uncover mechanisms behind uveal melanoma resistance

New research from the University of Pittsburgh explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient's T cells outside the body before reinfusing them, can successfully treat this rare and aggressive cancer.

16 Apr 2024

Arabica coffee's genetic legacy unveiled

The key to growing coffee plants that can better resist climate change in the decades to come may lie in the ancient past.

15 Apr 2024

New class of AI tackles complex diseases by incorporating scientific knowledge

Mayo Clinic researchers recently invented a new class of artificial intelligence (AI) algorithms called hypothesis-driven AI that are a significant departure from traditional AI models which learn solely from data.

15 Apr 2024

Texas A&M scientists elucidate how phages disarm antibiotic-resistant bacteria

Bacterial infections pose significant challenges to agriculture and medicine, especially as cases of antibiotic-resistant bacteria continue to rise.

15 Apr 2024

Study reveals how aberrant epigenetic regulation contributes to aggressive pediatric brain tumors

A new study conducted by researchers at Tampere University and Tampere University Hospital revealed how aberrant epigenetic regulation contributes to the development of atypical teratoid/rhabdoid (AT/RT) tumors, which are aggressive brain tumors that mainly affect young children.

15 Apr 2024

First comprehensive atlas sheds new light on processes underlying age-related muscle changes

How muscle changes with aging, and tries to fight its effects, is now better understood at the cellular and molecular level with the first comprehensive atlas of aging muscles in humans.

15 Apr 2024

Tiny DNA circles are key drivers of cancer formation, study suggests

Tiny circles of DNA that defy the accepted laws of genetics are key drivers of cancer formation, according to an international study led by researchers at Stanford Medicine.

15 Apr 2024

Study unlocks genetic secrets in APOEε4 carriers that could defend against Alzheimer's

Researchers utilized whole-genome sequencing and pathway analysis to uncover protective genetic variations against Alzheimer's disease in APOEε4 carriers, revealing a crucial role for extracellular matrix-related genes in mitigating the disease's progression.

15 Apr 2024

Understanding the role of genetic variants in male infertility

Approximately one in seven couples face difficulties conceiving a child naturally. Half of these cases are due to male infertility – either caused by the complete absence or low number of mature sperm.

13 Apr 2024

Breakthrough study reveals melanoma's resistance tactics to targeted therapy

Melanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to alleviate the health burden of the disease. Important advances in recent years include doctors using genetic tests to look for specific mutations they can target for more personalised, effective treatment.

13 Apr 2024

Genes News and Research

Study reveals accelerated progression of Alzheimer's in people with Down syndrome

Study reveals molecular changes in brain cells with Lewy bodies

Study reveals novel approach to promote efficient uptake of ASOs into cancer cells

Study reveals human gut plasmid with biomarker potential

Placental IGFBP1: A key factor in development of gestational diabetes

Pitt researchers uncover mechanisms behind uveal melanoma resistance

Arabica coffee's genetic legacy unveiled

New class of AI tackles complex diseases by incorporating scientific knowledge

Texas A&M scientists elucidate how phages disarm antibiotic-resistant bacteria

Study reveals how aberrant epigenetic regulation contributes to aggressive pediatric brain tumors

First comprehensive atlas sheds new light on processes underlying age-related muscle changes

Tiny DNA circles are key drivers of cancer formation, study suggests

Study unlocks genetic secrets in APOEε4 carriers that could defend against Alzheimer's

Understanding the role of genetic variants in male infertility

Breakthrough study reveals melanoma's resistance tactics to targeted therapy

Meta-analysis uncovers stress-responsive genes in Arabidopsis

Unveiling the key role of RNA modification in HIV-1 survival and replication

New genetic variants could raise a woman's risk of cervical cancer from HPV infections

Study sheds light on how androgens shape sex differences at the cellular and molecular levels

Study unlocks how cortisone activates the body’s natural “brakes” on inflammation

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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